Biography
Claire complete her DPhil (PhD) at the University of Oxford with her doctoral research focusing on modelling monogenic forms of diabetes in human beta cell models. Following this, she worked as a postdoc at University College London, where she investigated the neurocognitive phenotype of argininosuccinate lyase deficiency. Her current research is optimising beta cell differentiation to better improve functional outcomes. Her research interests include stem cells, modelling of disease and optimisation of differentiation protocols.
Research
Islet Biology Research Group
Our group studies the fundamental science of islets of Langerhans, from the molecular biology of beta-cells to their effects on whole body physiology. We research the mechanisms of islet dysfunction during type 2 diabetes and gestational diabetes, identify novel therapeutic targets, and work to improve islet transplantation therapy for type 1 diabetes.
Research
Islet Biology Research Group
Our group studies the fundamental science of islets of Langerhans, from the molecular biology of beta-cells to their effects on whole body physiology. We research the mechanisms of islet dysfunction during type 2 diabetes and gestational diabetes, identify novel therapeutic targets, and work to improve islet transplantation therapy for type 1 diabetes.