Dr Debashis Sarker Academics Senior Lecturer and Consultant in Medical Oncology Contact details debashis.sarker@kcl.ac.uk
Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer Sarker, D., 1 Dec 2020, In : Nature Communications. 11, 1, 4841. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41467-020-18636-w The eIF4A inhibitor silvestrol sensitizes T-47D ductal breast carcinoma cells to external-beam radiotherapy Webb, T. E., Davies, M., Maher, J. & Sarker, D., Sep 2020, In : Clinical and Translational Radiation Oncology. 24, p. 123-126 4 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.ctro.2020.07.002 First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor Plummer, R., Dua, D., Cresti, N., Drew, Y., Stephens, P., Foegh, M., Knudsen, S., Sachdev, P., Mistry, B. M., Dixit, V., McGonigle, S., Hall, N., Matijevic, M., McGrath, S. & Sarker, D., 18 Aug 2020, In : British Journal of Cancer. 123, 4, p. 525-533 9 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41416-020-0916-5 MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial Sarker, D., 1 Aug 2020, In : Clinical Cancer Research. 26, 15, p. 3936-3946 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1158/1078-0432.CCR-20-0414 Serum Immunoglobulin G Is Associated With Decreased Risk of Pancreatic Cancer in the Swedish AMORIS Study Sollie, S., Santaolalla, A., Michaud, D. S., Sarker, D., Karagiannis, S. N., Josephs, D. H., Hammar, N., Walldius, G., Garmo, H., Holmberg, L., Jungner, I. & Van Hemelrijck, M., 28 Feb 2020, In : Frontiers in oncology. 10, p. 263 263. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.3389/fonc.2020.00263 Serum immunoglobulin G is associated with decreased risk of pancreatic cancer in the Swedish AMORIS study Sollie, S., Santaolalla, A., Michaud, D. S., Sarker, D., Karagiannis, S. N., Josephs, D. H., Hammar, N., Walldius, G., Garmo, H., Holmberg, L., Jungner, I. & Van Hemelrijck, M., 14 Feb 2020, (Accepted/In press) In : Frontiers in oncology. Research output: Contribution to journal - Article NET-02 trial protocol: a multicentre, randomised, parallel group, open-label, phase II, single-stage selection trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients with progressive poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC) Sarker, D., 5 Feb 2020, In : BMJ Open. 10, 2, e034527. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1136/bmjopen-2019-034527 First-in-human phase i study of fisogatinib (BLU-554) validates aberrant FGF19 signaling as a driver event in hepatocellular carcinoma Kim, R. D., Sarker, D., Meyer, T., Yau, T., Macarulla, T., Park, J. W., Choo, S. P., Hollebecque, A., Sung, M. W., Lim, H. Y., Mazzaferro, V., Trojan, J., Zhu, A. X., Yoon, J. H., Sharma, S., Lin, Z. Z., Chan, S. L., Faivre, S., Feun, L. G., Yen, C. J. & 15 others, Dufour, J. F., Palmer, D. H., Llovet, J. M., Manoogian, M., Tugnait, M., Stransky, N., Hagel, M., Kohl, N. E., Lengauer, C., Sherwin, C. A., Schmidt-Kittler, O., Hoeflich, K. P., Shi, H., Wolf, B. B. & Kang, Y. K., 1 Dec 2019, In : Cancer discovery. 9, 12, p. 1696-1707 12 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1158/2159-8290.CD-19-0555 Chronic inflammation markers are associated with risk of pancreatic cancer in the Swedish AMORIS cohort study Sollie, S., Michaud, D. S., Sarker, D., Karagiannis, S. N., Josephs, D. H., Hammar, N., Santaolalla, A., Walldius, G., Garmo, H., Holmberg, L., Jungner, I. & Van Hemelrijck, M., 29 Aug 2019, In : BMC Cancer. 19, 1, 858. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1186/s12885-019-6082-6 Hepatocellular Carcinoma as a Complication of Vascular Disease of the Liver After Fontan Procedure Mazzarelli, C., Cannon, M. D., Hudson, M., Heaton, N., Sarker, D., Kane, P., Quaglia, A. & Suddle, A., 1 Feb 2019, In : Hepatology. 69, 2, p. 911-913 3 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1002/hep.30194 View all publications