Professor Debbie Shawcross Academics Professor of Hepatology and Chronic Liver Failure Contact details debbie.shawcross@kcl.ac.uk +44 (0) 20 7848 5945 +44 (0) 20 3299 3713
Intestinal virome in patients with alcoholic hepatitis Jiang, L., Lang, S., Duan, Y., Zhang, X., Gao, B., Chopyk, J., Schwanemann, L. K., Ventura-Cots, M., Bataller, R., Bosques-Padilla, F., Verna, E. C., Abraldes, J. G., Brown, R. S., Vargas, V., Altamirano, J., Caballería, J., Shawcross, D. L., Ho, S. B., Louvet, A., Lucey, M. R. & 9 others, Mathurin, P., Garcia-Tsao, G., Kisseleva, T., Brenner, D. A., Tu, X. M., Stärkel, P., Pride, D., Fouts, D. E. & Schnabl, B., Dec 2020, In : Hepatology. 72, 6, p. 2182-2196 15 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1002/hep.31459 Targeting the gut-liver-immune axis to treat cirrhosis Tranah, T. H., Edwards, L. A., Schnabl, B. & Shawcross, D. L., 15 Oct 2020, In : Gut. 320786. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1136/gutjnl-2020-320786 Foreword Shawcross, D. L., 1 Sep 2020, In : British journal of nursing (Mark Allen Publishing). 29, Sup17, p. S3 Research output: Contribution to journal - Editorial. DOIs: https://doi.org/10.12968/bjon.2020.29.Sup17.S3 Faecal microbiota transplant to ERadicate gastrointestinal carriage of Antibiotic Resistant Organisms (FERARO): a prospective, randomised placebo-controlled feasibility trial Merrick, B., Robinson, E., Bunce, C., Allen, L., Bisnauthsing, K., Izundu, C. C., Bell, J., Amos, G., Shankar-Hari, M., Goodman, A., Shawcross, D. L. & Goldenberg, S. D., 25 May 2020, In : BMJ Open. 10, 5, p. e038847 e038847. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1136/bmjopen-2020-038847 Protocol: A prospective, randomised placebo-controlled feasibility trial of Faecal microbiota Transplant to ERadicate gastrointestinal carriage of Antibiotic Resistant Organisms (FERARO) Merrick, B., Robinson, E. J., Bunce, C., Allen, L., Bisnauthsing, K., Izundu, C. C., Bell, J., Amos, G., Shankar-Hari, M., Goodman, A., Shawcross, D. & Goldenberg, S., 3 Apr 2020, (Accepted/In press) In : BMJ Open. Research output: Contribution to journal - Article Severe alcohol-related liver disease admissions post-COVID-19 lockdown: Canary in the coal mine? Cargill, Z., Kattiparambil, S., Hansi, N., Barnabas, A., Shawcross, D. L., Williams, R. & Agarwal, K., 2020, (Accepted/In press) In : Frontline Gastroenterology. Research output: Contribution to journal - Letter. DOIs: https://doi.org/10.1136/flgastro-2020-101693 Hepatic encephalopathy Ryan, J. M. & Shawcross, D. L., 1 Dec 2019, In : Medicine (United Kingdom). 47, 12, p. 833-837 5 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1016/j.mpmed.2019.09.015 Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease Duan, Y., Llorente, C., Lang, S., Brandl, K., Chu, H., Jiang, L., White, R. C., Clarke, T. H., Nguyen, K., Torralba, M., Shao, Y., Liu, J., Hernandez-Morales, A., Lessor, L., Rahman, I. R., Miyamoto, Y., Ly, M., Gao, B., Sun, W., Kiesel, R. & 26 others, Hutmacher, F., Lee, S., Ventura-Cots, M., Bosques-Padilla, F., Verna, E. C., Abraldes, J. G., Brown, R. S., Vargas, V., Altamirano, J., Caballería, J., Shawcross, D. L., Ho, S. B., Louvet, A., Lucey, M. R., Mathurin, P., Garcia-Tsao, G., Bataller, R., Tu, X. M., Eckmann, L., van der Donk, W. A., Young, R., Lawley, T. D., Stärkel, P., Pride, D., Fouts, D. E. & Schnabl, B., 21 Nov 2019, In : Nature. 575, 7783, p. 505-511 7 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41586-019-1742-x PROFIT: PROspective, Randomised Placebo-controlled Feasibility Trial of Faecal Microbiota Transplantation in Cirrhosis Interim Analysis Woodhouse, C., Kronsten, V., Zamalloa, A., Hatton, G., Patel, V. C., Goldenberg, S. & Shawcross, D. L., Sep 2019, In : American Journal of Gastroenterology. 114, p. S5-S7 Research output: Contribution to journal - Meeting Abstract Rifaximin reduces the incidence of spontaneous bacterial peritonitis, variceal bleeding and all-cause admissions in patients on the liver transplant waiting list Salehi, S., Tranah, T. H., Lim, S., Heaton, N., Heneghan, M., Aluvihare, V., Patel, V. C. & Shawcross, D. L., Aug 2019, In : Alimentary Pharmacology & Therapeutics. 50, 4, p. 435-441 7 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/apt.15326 View all publications
13 November 2019 Phage therapy shows promise for treating Alcoholic Liver Disease Study shows treating mice with bacteriophages clears bacteria and eliminates the disease in mice.