Dr Alan Ramsay Academics Supervisors Reader (Associate Professor) in Lymphoma Biology Research subject areas Cancer Immunology Contact details alan.ramsay@kcl.ac.uk
Extracellular vesicle secretion by leukemia cells in vivo promotes CLL progression by hampering antitumor T-cell responses Gargiulo, E., Viry, E., Morande, P. E., Largeot, A., Gonder, S., Xian, F., Ioannou, N., Benzarti, M., Kleine Borgmann, F. B., Mittelbronn, M., Dittmar, G., Nazarov, P. V., Meiser, J., Stamatopoulos, B., Ramsay, A. G., Moussay, E. & Paggetti, J., 5 Oct 2022, (E-pub ahead of print) In: Blood Cancer Discovery. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1158/2643-3230.BCD-22-0029 Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells Uhl, B., Prochazka, K. T., Pansy, K., Wenzl, K., Strobl, J., Baumgartner, C., Szmyra, M. M., Waha, J. E., Wolf, A., Tomazic, P. V., Steinbauer, E., Steinwender, M., Friedl, S., Weniger, M., Küppers, R., Pichler, M., Greinix, H. T., Stary, G., Ramsay, A. G., Apollonio, B., & 4 othersFeichtinger, J., Beham-Schmid, C., Neumeister, P. & Deutsch, A. J., 17 Jul 2022, In: International Journal of Molecular Sciences. 23, 14, 7874. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/ijms23147874 Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures Vaca, A. M., Ioannou, N., Sivina, M., Vlachonikola, E., Clise-Dwyer, K., Kim, E., Li, D., Ma, Q., Ferrajoli, A., Estrov, Z., Wierda, W. G., Patten, P. E. M., Ramsay, A. G. & Burger, J. A., May 2022, In: Leukemia. 36, 5, p. 1324-1335 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41375-022-01519-y Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity Hanna, B. S., Llaó-Cid, L., Iskar, M., Roessner, P. M., Klett, L. C., Wong, J. K. L., Paul, Y., Ioannou, N., Öztürk, S., Mack, N., Kalter, V., Colomer, D., Campo, E., Bloehdorn, J., Stilgenbauer, S., Dietrich, S., Schmidt, M., Gabriel, R., Rippe, K., Feuerer, M., & 4 othersRamsay, A. G., Lichter, P., Zapatka, M. & Seiffert, M., 14 Dec 2021, In: Immunity. 54, 12, p. 2825-2841.e10 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.immuni.2021.11.004 Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma Graham, C. E., Jozwik, A., Quartey-Papafio, R., Ioannou, N., Metelo, A. M., Scala, C., Dickson, G., Stewart, O., Almena-Carrasco, M., Peranzoni, E., Ramsay, A. G., Patten, P. E. M., Pertel, T., Farzaneh, F., Dupouy, S., Pepper, A. & Benjamin, R., Dec 2021, In: Leukemia. 35, 12, p. 3581-3584 4 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41375-021-01324-z Targeting the tumor microenvironment in chronic lymphocytic leukemia Svanberg, R., Janum, S., Patten, P. E. M., Ramsay, A. G. & Niemann, C. U., Sep 2021, In: Haematologica. 106, 9, p. 2312-2324 13 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3324/haematol.2020.268037 Immunomodulatory drugs for the treatment of b cell malignancies Ioannou, N., Jain, K. & Ramsay, A. G., 2 Aug 2021, In: International Journal of Molecular Sciences. 22, 16, 8572. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3390/ijms22168572 ImmunoCluster provides a computational framework for the non-specialist to profile high- dimensional cytometry data Opzoomer, J. W., Timms, J. A., Blighe, K., Mourikis, T. P., Chapuis, N., Bekoe, R., Kareemaghay, S., Nocerino, P., Apollonio, B., Ramsay, A. G., Tavassoli, M., Harrison, C., Ciccarelli, F. D., Parker, P., Fontenay, M., Barber, P. R., Arnold, J. N. & Kordasti, S., Apr 2021, In: eLife. 10, e62915. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.7554/eLife.62915 Understanding the Immune-Stroma Microenvironment in B Cell Malignancies for Effective Immunotherapy Apollonio, B., Ioannou, N., Papazoglou, D. & Ramsay, A. G., 25 Mar 2021, In: Frontiers in oncology. 11, 626818. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3389/fonc.2021.626818 A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice Patten, P. E. M., Ferrer, G., Chen, S. S., Kolitz, J. E., Rai, K. R., Allen, S. L., Barrientos, J. C., Ioannou, N., Ramsay, A. G. & Chiorazzi, N., 9 Mar 2021, In: Frontiers in Immunology. 12, 627020. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2021.627020 View all publications
8 February 2021 Researchers identify a combination therapy approach to help cold tumours respond to immunotherapy The discovery marks an important step for patients with chronic lymphocytic leukemia.