Dr Alan Ramsay Academics Supervisors Reader (Associate Professor) in Lymphoma Biology Contact details alan.ramsay@kcl.ac.uk
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity Hanna, B. S., Llaó-Cid, L., Iskar, M., Roessner, P. M., Klett, L. C., Wong, J. K. L., Paul, Y., Ioannou, N., Öztürk, S., Mack, N., Kalter, V., Colomer, D., Campo, E., Bloehdorn, J., Stilgenbauer, S., Dietrich, S., Schmidt, M., Gabriel, R., Rippe, K., Feuerer, M. & 4 others, Ramsay, A. G., Lichter, P., Zapatka, M. & Seiffert, M., 14 Dec 2021, In: Immunity. 54, 12, p. 2825-2841.e10 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.immuni.2021.11.004 Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma Graham, C. E., Jozwik, A., Quartey-Papafio, R., Ioannou, N., Metelo, A. M., Scala, C., Dickson, G., Stewart, O., Almena-Carrasco, M., Peranzoni, E., Ramsay, A. G., Patten, P. E. M., Pertel, T., Farzaneh, F., Dupouy, S., Pepper, A. & Benjamin, R., Dec 2021, In: Leukemia. 35, 12, p. 3581-3584 4 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41375-021-01324-z Targeting the tumor microenvironment in chronic lymphocytic leukemia Svanberg, R., Janum, S., Patten, P. E. M., Ramsay, A. G. & Niemann, C. U., Sep 2021, In: Haematologica. 106, 9, p. 2312-2324 13 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3324/haematol.2020.268037 Immunomodulatory drugs for the treatment of b cell malignancies Ioannou, N., Jain, K. & Ramsay, A. G., 2 Aug 2021, In: International Journal of Molecular Sciences. 22, 16, 8572. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3390/ijms22168572 ImmunoCluster provides a computational framework for the non-specialist to profile high- dimensional cytometry data Opzoomer, J. W., Timms, J. A., Blighe, K., Mourikis, T. P., Chapuis, N., Bekoe, R., Kareemaghay, S., Nocerino, P., Apollonio, B., Ramsay, A. G., Tavassoli, M., Harrison, C., Ciccarelli, F. D., Parker, P., Fontenay, M., Barber, P. R., Arnold, J. N. & Kordasti, S., Apr 2021, In: eLife. 10, e62915. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.7554/eLife.62915 Understanding the Immune-Stroma Microenvironment in B Cell Malignancies for Effective Immunotherapy Apollonio, B., Ioannou, N., Papazoglou, D. & Ramsay, A. G., 25 Mar 2021, In: Frontiers in oncology. 11, 626818. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3389/fonc.2021.626818 A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice Patten, P. E. M., Ferrer, G., Chen, S. S., Kolitz, J. E., Rai, K. R., Allen, S. L., Barrientos, J. C., Ioannou, N., Ramsay, A. G. & Chiorazzi, N., 9 Mar 2021, In: Frontiers in Immunology. 12, 627020. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2021.627020 Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy Ioannou, N., Hagner, P. R., Stokes, M., Gandhi, A. K., Apollonio, B., Fanous, M., Papazoglou, D., Sutton, L-A., Rosenquist, R., Amini, R-M., Chiu, H., Lopez-Girona, A., Janardhanan, P., Awan, F. T., Jones, J., Kay, N. E., Shanafelt, T. D., Tallman, M. S., Stamatopoulos, K., Patten, P. E. M. & 2 others, Vardi, A. & Ramsay, A. G., 14 Jan 2021, In: Blood. 137, 2, p. 216-231 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1182/blood.2020006073 Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data Timms, J. A., Opzoomer, J. W., Blighe, K., Apollonio, B., Mourikis, T., Chapuis, N., Bekoe, R., Ramsay, A. G., McLornan, D. P., Harrison, C., Barber, P. R., Parker, P., Fontenay, M., Arnold, J. N. & Kordasti, S., 5 Nov 2020, In: Blood. 136 Research output: Contribution to journal › Meeting Abstract › peer-review. DOIs: https://doi.org/10.1182/blood-2020-140258 T-Cell Dynamics in Chronic Lymphocytic Leukemia under Different Treatment Modalities Vardi, A., Vlachonikola, E., Papazoglou, D., Psomopoulos, F., Kotta, K., Ioannou, N., Galigalidou, C., Gemenetzi, K., Pasentsis, K., Kotouza, M., Koravou, E., Scarfò, L., Iskas, M., Stavroyianni, N., Ghia, P., Anagnostopoulos, A., Kouvatsi, A., Ramsay, A. G., Stamatopoulos, K. & Chatzidimitriou, A., 30 Sep 2020, In: Clinical Cancer Research. 26, 18, p. 4958-4969 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1158/1078-0432.CCR-19-3827 View all publications
8 February 2021 Researchers identify a combination therapy approach to help cold tumours respond to immunotherapy The discovery marks an important step for patients with chronic lymphocytic leukemia.