James Garnett Dr James Garnett Academics Reader in Microbial Structural Biology Contact details james.garnett@kcl.ac.uk 020 7188 4362
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling Structural Modeling of T9SS Outer Membrane Proteins and Their Complexes The Legionella collagen-like protein employs a distinct binding mechanism for the recognition of host glycosaminoglycans Autoantibody and T cell responses to oxidative post-translationally modified insulin neoantigenic peptides in type 1 diabetes Editorial: Intersection of biophysical and structural approaches in vaccine design How to study biofilms: technological advancements in clinical biofilm research I shall be released: Assembly platform dynamics during type II secretion The influence of ions on the lubricative abilities of mucin and the role of sialic acids Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation Structural Model of a Porphyromonas gingivalis type IX Secretion System Shuttle Complex Structure Determination of Microtubules and Pili: Past, Present, and Future Directions Assay for Assessing Mucin Binding to Bacteria and Bacterial Proteins Comparative Microbial Profiles of Caries and Black Extrinsic Tooth Stain in Primary Dentition Editorial: Glycans as Players in Host-Microbe Interactions: A Structural Perspective Structure Determination of Microtubules and Pili: Past, Present, and Future Directions The Relationship Between Mucins and Ulcerative Colitis: A Systematic Review Discovery of a new neisseria gonorrhoeae type iv pilus assembly factor, tfpc GloBody Technology: Detecting Anti-Drug Antibody against VH/VL domains Structure, dynamics and cellular insight into novel substrates of the Legionella pneumophila type II secretion system Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers Scalable Geometrically Designed Protein Cages Assembled via Genetically Encoded Split Inteins The fungal ribonuclease-like effector protein CSEP0064/BEC1054 represses plant immunity and interferes with degradation of host ribosomal RNA Type II secretion-dependent aminopeptidase lapa and acyltransferase plac are redundant for nutrient acquisition during Legionella pneumophila intracellular infection of amoebas The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system Crystal structure and analysis of HdaB: The enteroaggregative Escherichia coli AAF/IV pilus tip protein Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals Purification, crystallization and preliminary X-ray diffraction analysis of the Escherichia coli common pilus chaperone EcpB Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases Crystal structures of stapled and hydrogen bond surrogate peptides targeting a fully buried protein-helix interaction Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation The peptide-binding cavity is essential for ALS3-mediated adhesion of Candida albicans to human cells Interactions in bacterial biofilm development: A structural perspective Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus Complete 1H, 13C and 15N NMR assignments for donor-strand complemented AafA, the major pilin of aggregative adherence fimbriae (AAF/II) from enteroaggregative E. coli Crystallization and initial crystallographic analysis of AafA: The major adhesive subunit of the enteroaggregative Escherichia coli AAF/II pilus Crystallization and initial crystallographic analysis of the Streptococcus parasanguinis FW213 Fap1 - NRα adhesive domain at pH 5.0 The role of Sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria Tenella Bacterial guanine nucleotide exchange factors SopE-Like and WxxxE effectors EspM2 is a RhoA guanine nucleotide exchange factor Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii View all publications