Professor James Mason Academics Professor of Membrane Biochemistry Contact details james.mason@kcl.ac.uk +44 20 7848 4813 @DrJamesMason
Bolaamphiphile analogues of 12-bis-THA Cl2 are potent antimicrobial therapeutics with distinct mechanisms of action against bacterial, mycobacterial, and fungal pathogens Di Blasio, S., Clarke, M., Hind, C. K., Asai, M., Laurence, L., Benvenuti, A., Hassan, M., Semenya, M. M. D., Man, D. K-W., Horrocks, V., Manzo, G., Van Der Lith, S., Gentile, E., Lam, C., Annette, C., Bosse, J., Li, Y., Panaretou, B., Langford, P., Robertson, B. D., & 4 othersLam, J. K. W., Sutton, J., McArthur, M. & Mason, J., 13 Dec 2022, (E-pub ahead of print) In: mSphere. Research output: Contribution to journal › Article › peer-review Design and manufacture of a lyophilised faecal microbiota capsule formulation to GMP standards Zain, N. M. M., ter Linden, D., Lilley, A. K., Royall, P. G., Tsoka, S., Bruce, K. D., Mason, A. J., Hatton, G. B., Allen, E., Goldenberg, S. D. & Forbes, B., Oct 2022, In: Journal of Controlled Release. 350, p. 324-331 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jconrel.2022.08.012 Nuclear magnetic resonance metabolomics of symbioses between bacterial vaginosis associated bacteria Horrocks, V., Hind, C. K., Wand, M. E., Fady, P-E., Chan, J., Hopkins, J., Houston, G., Tribe, R., Sutton, J. & Mason, J., 29 Jun 2022, In: mSphere. 7, 3, p. e0016622 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1128/msphere.00166-22 Neutrophils Dominate the Cervical Immune Cell Population in Pregnancy and Their Transcriptome Correlates With the Microbial Vaginal Environment Mohd Zaki, A., Hadingham, A., Flaviani, F., Haque, Y., Mi, J. D., Finucane, D., Dalla Valle, G., Mason, A. J., Saqi, M., Gibbons, D. L. & Tribe, R. M., 14 Jun 2022, In: Frontiers in microbiology. 13, 904451. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fmicb.2022.904451 Temporin B forms hetero-oligomers with Temporin L, modifies its membrane activity and increases the cooperativity of its antibacterial pharmacodynamic profile Ferguson, P., Clarke, M., Manzo, G., Hind, C. K., Clifford, M., Sutton, J., Lorenz, C., Phoenix, D. & Mason, J., 7 Jun 2022, In: Biochemistry. 61, 11, p. 1029-1040 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acs.biochem.1c00762 Design of a new cell penetrating peptide for DNA, siRNA and mRNA delivery Ali, S., Dussouillez, C., Padilla, B., Frisch, B., Mason, J. & Kichler, A., 2 Dec 2021, In: JOURNAL OF GENE MEDICINE. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/jgm.3401 Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling Bock, L. J., Ferguson, P., Clarke, M., Pumpitakkul, V., Wand, M. E., Fady, P-E., Allison, L., Fleck, R., Shepherd, M., Mason, J. & Sutton, J. M., 9 Sep 2021, In: Communications Biology. 4, 1, 1058. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s42003-021-02566-4 Cervicovaginal microbiota and metabolome predict preterm birth risk in an ethnically diverse cohort Flaviani, F., Hezelgrave, N. L., Kanno, T., Prosdocimi, E. M., Chin-Smith, E., Ridout, A. E., von Maydell, D. K., Mistry, V., Wade, W. G., Shennan, A. H., Dimitrakopoulou, K., Seed, P. T., Mason, A. J. & Tribe, R. M., 23 Aug 2021, In: JCI Insight. 6, 16, 16 p., e149257. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1172/jci.insight.149257 Impacts of metabolism and organic acids on cell wall composition and Pseudomonas aeruginosa susceptibility to membrane active antimicrobials Manzo, G., Gianfanti, F., Hind, C. K., Allison, L., Clarke, M., Hohenbichler, J., Limantoro, I., Martin, B., Do Carmo Silva, P., Ferguson, P., Hodgson-Casson, A., Fleck, R., Sutton, J. M., Phoenix, D. & Mason, J., 13 Aug 2021, In: ACS Infectious Disease. 7, 8, p. 2310-2323 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acsinfecdis.1c00002 Optimization of PEGylated KL4 Peptide for siRNA Delivery with Improved Pulmonary Tolerance Qiu, Y., Clarke, M., Wan, L., Lo, J., Mason, J. & Lam, J. K. W., 7 Jun 2021, In: Molecular Pharmaceutics. 18, 6, p. 2218-2232 15 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acs.molpharmaceut.0c01242 View all publications
13 October 2020 Six new Studentships for Institute of Pharmaceutical Science The School of Cancer & Pharmaceutical Science are pleased to announce that there are six new…