Professor Manuel Mayr Academics British Heart Foundation Professor of Cardiovascular Proteomics Contact details manuel.mayr@kcl.ac.uk +44 (0) 02 7848 5446 @Vascular_Prot
Preclinical development of a miR-132 inhibitor for heart failure treatment Foinquinos, A., Batkai, S., Genschel, C., Viereck, J., Rump, S., Gyöngyösi, M., Traxler, D., Riesenhuber, M., Spannbauer, A., Lukovic, D., Weber, N., Zlabinger, K., HaÅ¡imbegović, E., Winkler, J., Fiedler, J., Dangwal, S., Fischer, M., Roche, J. D. L., Wojciechowski, D., Kraft, T. & 8 others, Garamvölgyi, R., Neitzel, S., Chatterjee, S., Yin, X., Bär, C., Mayr, M., Xiao, K. & Thum, T., 1 Dec 2020, In : Nature Communications. 11, 1, 633. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41467-020-14349-2 Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart Tocchetti, C. G., Ameri, P., de Boer, R. A., D'Alessandra, Y., Russo, M., Sorriento, D., Ciccarelli, M., Kiss, B., Bertrand, L., Dawson, D., Falcao-Pires, I., Giacca, M., Hamdani, N., Linke, W. A., Mayr, M., van der Velden, J., Zacchigna, S., Ghigo, A., Hirsch, E., Lyon, A. R. & 5 others, Görbe, A., Ferdinandy, P., Madonna, R., Heymans, S. & Thum, T., 1 Sep 2020, In : Cardiovascular Research. 116, 11, p. 1820-1834 15 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1093/cvr/cvaa222 Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement Brayson, D., Holohan, S. J., Bardswell, S. C., Arno, M., Lu, H., Jensen, H. K., Tran, P. K., Barallobre-Barreiro, J., Mayr, M., Dos Remedios, C. G., Tsang, V. T., Frigiola, A. & Kentish, J. C., 18 Aug 2020, In : Journal of the American Heart Association. 9, 16, p. e015342 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1161/JAHA.119.015342 Platelet '-omics' in health and cardiovascular disease Gutmann, C., Joshi, A. & Mayr, M., Aug 2020, In : Atherosclerosis. 307, p. 87-96 10 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1016/j.atherosclerosis.2020.05.022 The right ventricle of Tetralogy of Fallot patients undergoing pulmonary valve replacement has normal myofilament function but shows perturbations to the expression of extracellular matrix genes Brayson, D., Holohan, S-J., Bardswell, S. C., Arno, M., Lu, H., Jensen, H. K., Kiet Tran, P., Barallobre-Barreiro, J., Mayr, M., G.dos Remedios, C., T. Tsang, V., Frigiola, A. & Kentish, J., 28 May 2020, (Accepted/In press) In : Journal of the American Heart Association. Research output: Contribution to journal - Article Extracellular Matrix in Vascular Disease, Part 2/4: JACC Focus Seminar Barallobre-Barreiro, J., Loeys, B., Mayr, M., Rienks, M., Verstraeten, A. & Kovacic, J. C., 5 May 2020, In : Journal of the American College of Cardiology. 75, 17, p. 2189-2203 15 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1016/j.jacc.2020.03.018 Micrornas as promising biomarkers of platelet activity in antiplatelet therapy monitoring Krammer, T. L., Mayr, M. & Hackl, M., 2 May 2020, In : International Journal of Molecular Sciences. 21, 10, 3477. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.3390/ijms21103477 ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis Capoulade, R., Torzewski, M., Mayr, M., Chan, K. L., Mathieu, P., Bossé, Y., Dumesnil, J. G., Tam, J., Teo, K. K., Burnap, S. A., Schmid, J., Gobel, N., Franke, U. F. W., Sanchez, A., Witztum, J. L., Yang, X., Yeang, C., Arsenault, B., Després, J. P., Pibarot, P. & 1 others, Tsimikas, S., 1 May 2020, In : Heart. 106, 10, p. 738-745 8 p., 315840. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1136/heartjnl-2019-315840 Circulating microRNA levels indicate platelet and leukocyte activation in endotoxemia despite platelet p2y12 inhibition Braza-Boïls, A., Barwari, T., Gutmann, C., Thomas, M. R., Judge, H. M., Joshi, A., Pechlaner, R., Shankar-Hari, M., Ajjan, R. A., Sabroe, I., Storey, R. F. & Mayr, M., 2 Apr 2020, In : International Journal of Molecular Sciences. 21, 8, 2897. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.3390/ijms21082897 FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease-Associated Genetic Variant and Influences Monocyte Transendothelial Migration Yang, X., Yang, W., McVey, D. G., Zhao, G., Hu, J., Poston, R. N., Ren, M., Willeit, K., Coassin, S., Willeit, J., Webb, T. R., Samani, N. J., Mayr, M., Kiechl, S. & Ye, S., 18 Feb 2020, In : Journal of the American Heart Association. 9, 4, e014333. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1161/JAHA.119.014333 View all publications
6 July 2020 Quest for biomarkers in blood samples of COVID-19 patients to better understand host response Researchers from the School of Cardiovascular Medicine & Sciences have been analysing blood samples…