Professor Manuel Mayr Academics British Heart Foundation Professor of Cardiovascular Proteomics Contact details manuel.mayr@kcl.ac.uk +44 (0) 02 7848 5446 @Vascular_Prot
Preclinical development of a miR-132 inhibitor for heart failure treatment Foinquinos, A., Batkai, S., Genschel, C., Viereck, J., Rump, S., Gyöngyösi, M., Traxler, D., Riesenhuber, M., Spannbauer, A., Lukovic, D., Weber, N., Zlabinger, K., HaÅ¡imbegović, E., Winkler, J., Fiedler, J., Dangwal, S., Fischer, M., Roche, J. D. L., Wojciechowski, D., Kraft, T. & 8 others, Garamvölgyi, R., Neitzel, S., Chatterjee, S., Yin, X., Bär, C., Mayr, M., Xiao, K. & Thum, T., 1 Dec 2020, In : Nature Communications. 11, 1, 633. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41467-020-14349-2 Extracellular Matrix in Vascular Disease, Part 2/4: JACC Focus Seminar Barallobre-Barreiro, J., Loeys, B., Mayr, M., Rienks, M., Verstraeten, A. & Kovacic, J. C., 5 May 2020, In : Journal of the American College of Cardiology. 75, 17, p. 2189-2203 15 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1016/j.jacc.2020.03.018 Circulating microRNA levels indicate platelet and leukocyte activation in endotoxemia despite platelet p2y12 inhibition Braza-Boïls, A., Barwari, T., Gutmann, C., Thomas, M. R., Judge, H. M., Joshi, A., Pechlaner, R., Shankar-Hari, M., Ajjan, R. A., Sabroe, I., Storey, R. F. & Mayr, M., 2 Apr 2020, In : International Journal of Molecular Sciences. 21, 8, 2897. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.3390/ijms21082897 FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease-Associated Genetic Variant and Influences Monocyte Transendothelial Migration Yang, X., Yang, W., McVey, D. G., Zhao, G., Hu, J., Poston, R. N., Ren, M., Willeit, K., Coassin, S., Willeit, J., Webb, T. R., Samani, N. J., Mayr, M., Kiechl, S. & Ye, S., 18 Feb 2020, In : Journal of the American Heart Association. 9, 4, e014333. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1161/JAHA.119.014333 Aspirin, clopidogrel and prasugrel monotherapy in patients with type 2 diabetes mellitus: A double-blind randomised controlled trial of the effects on thrombotic markers and microRNA levels Parker, W. A. E., Schulte, C., Barwari, T., Phoenix, F., Pearson, S. M., Mayr, M., Grant, P. J., Storey, R. F. & Ajjan, R. A., 7 Jan 2020, In : Cardiovascular Diabetology. 19, 1, 3. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1186/s12933-019-0981-3 A plasma proteogenomic signature for fibromuscular dysplasia Olin, J. W., Di Narzo, A. F., D'Escamard, V., Kadian-Dodov, D., Cheng, H., Georges, A., King, A., Thomas, A., Barwari, T., Michelis, K. C., Bouchareb, R., Bander, E., Anyanwu, A., Stelzer, P., Filsoufi, F., Florman, S., Civelek, M., Debette, S., Jeunemaitre, X., Björkegren, J. L. M. & 4 others, Mayr, M., Bouatia-Naji, N., Hao, K. & Kovacic, J. C., 1 Jan 2020, In : Cardiovascular Research. 116, 1, p. 63-77 15 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1093/cvr/cvz219 ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis Capoulade, R., Torzewski, M., Mayr, M., Chan, K. L., Mathieu, P., Bossé, Y., Dumesnil, J. G., Tam, J., Teo, K. K., Burnap, S. A., Schmid, J., Gobel, N., Franke, U. F. W., Sanchez, A., Witztum, J. L., Yang, X., Yeang, C., Arsenault, B., Després, J. P., Pibarot, P. & 1 others, Tsimikas, S., 1 Jan 2020, (Accepted/In press) In : Heart. 315840. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1136/heartjnl-2019-315840 Pkm2 regulates cardiomyocyte cell cycle and promotes cardiac regeneration Magadum, A., Singh, N., Kurian, A. A., Munir, I., Mehmood, T., Brown, K., Sharkar, M. T. K., Chepurko, E., Sassi, Y., Oh, J. G., Lee, P., Santos, C. X. C., Gaziel-Sovran, A., Zhang, G., Cai, C. L., Kho, C., Mayr, M., Shah, A. M., Hajjar, R. J. & Zangi, L., 1 Jan 2020, (Accepted/In press) In : Circulation. p. 1249-1265 17 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1161/CIRCULATIONAHA.119.043067 Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in disease Barallobre-Barreiro, J., Woods, E., Bell, R. E., Easton, J. A., Hobbs, C., Eager, M., Baig, F., MacKenzie Ross, A., Mallipeddi, R., Powell, B., Soldin, M., Mayr, M. & Shaw, T. J., 30 Oct 2019, In : Matrix Biology Plus. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.mbplus.2019.100016 TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation Grund, A., Szaroszyk, M., Korf-Klingebiel, M., Malek Mohammadi, M., Trogisch, F. A., Schrameck, U., Gigina, A., Tiedje, C., Gaestel, M., Kraft, T., Hegermann, J., Batkai, S., Thum, T., Perrot, A., Remedios, C. D., Riechert, E., Völkers, M., Doroudgar, S., Jungmann, A., Bauer, R. & 9 others, Yin, X., Mayr, M., Wollert, K. C., Pich, A., Xiao, H., Katus, H. A., Bauersachs, J., Müller, O. J. & Heineke, J., 1 Oct 2019, In : EMBO Molecular Medicine. 11, 10, e10018. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.15252/emmm.201810018 View all publications