
Professor Martyn Cobourne
Professor of Orthodontics
- Hon Consultant in Orthodontics, Guy’s and St Thomas’ NHS Foundation Trust
Research interests
- Dentistry
Biography
Martyn Cobourne graduated from King’s College London in 1990 and undertook specialty training in orthodontics at King’s College Hospital (1994-97). He was then awarded a Medical Research Council Clinical Training Fellowship and undertook a period of basic science research in Paul Sharpe’s laboratory at Guy’s Dental Hospital, which led to the award of a PhD (1998-2001). This research won the Senior Colgate Prize of the British Society of Dental Research in 2000.
Following a period of further clinical training, he was appointed as Senior Lecturer and Honorary Consultant in Orthodontics at King’s College London in 2004 and promoted to Professor of Orthodontics in 2011.
His research is primarily focused on the role of molecular signalling pathways during early development of the head and face, with a particular focus on the role of Sonic hedgehog signal transduction.
However, he is also interested in the effectiveness of contemporary orthodontic treatment interventions and has led a number of randomised clinical trials investigating the efficiency of orthodontic treatment.
He has published over 130 peer-reviewed articles and is the author of two successful orthodontic textbooks, the Handbook of Orthodontics (Elsevier) and Clinical Cases in Orthodontics (Wiley).
His research has won a number of prizes, including the British Orthodontic Society Chapman Prize for best research article (2014, 2016 and 2018) and the American Association of Orthodontists Dewel Award for best clinical research in 2019.
He has been invited to present a number of prestigious lectures, including the Charles Tomes Lecture at the Royal College of Surgeons, England (2015) and the Northcroft Lecture at the British Orthodontic Society Conference in 2018.
He was a Trustee and Director of Research at the British Orthodontic Society (2012-2016) and has been Editor-in-Chief of the Journal of Orthodontics since 2012. In 2017 he became a full member of the USA North Atlantic Division of the Angle Society of Orthodontists and was elected to the Board of Faculty of Dental Surgeons at the Royal College of Surgeons of England.
Clinical evaluation of marketed and non-marketed orthodontic products: are researchers now ahead of the times? A meta-epidemiological study
Alhussain, A., Cobourne, M. T., Pandis, N. & Seehra, J., Dec 2023, In: Progress in Orthodontics. 24, 1, 32.Research output: Contribution to journal › Article › peer-review
Duration of canine retraction with fixed appliances: A systematic review and meta-analysis
Wazwaz, F., Seehra, J., Carpenter, G. H., Papageorgiou, S. N. & Cobourne, M. T., Feb 2023, In: American Journal of Orthodontics and Dentofacial Orthopedics. 163, 2, p. 154-172 19 p.Research output: Contribution to journal › Review article › peer-review
Accounting for clustering is still not routinely undertaken in orthodontic studies
Sudiskumar, N., Cobourne, M. T., Pandis, N. & Seehra, J., 1 Feb 2023, In: European journal of orthodontics. 45, 1, p. 45-50 6 p.Research output: Contribution to journal › Article › peer-review
The prevalence of and factors influencing statistical testing of baseline characteristics in randomized controlled trials published in high-impact orthodontic journals
Alduwaisan, A., Hirst, L., Cobourne, M. T., Pandis, N. & Seehra, J., Mar 2023, In: American Journal of Orthodontics and Dentofacial Orthopedics. 163, 3, p. e34-e83Research output: Contribution to journal › Article › peer-review
Does the quality of orthodontic studies influence their Altmetric Attention Score?
Alsaif, T., Pandis, N., Cobourne, M. T. & Seehra, J., 2023, In: Korean Journal of Orthodontics. 53, 5, p. 328-335 8 p.Research output: Contribution to journal › Article › peer-review
Periodontal outcomes associated with impacted maxillary central incisor and canine teeth following surgical exposure and orthodontic alignment: a systematic review and meta-analysis
Seehra, J., Alshammari, A., Wazwaz, F., Papageorgiou, S. N., Newton, J. T. & Cobourne, M. T., 1 Oct 2023, In: European journal of orthodontics. 45, 5, p. 584-598 15 p.Research output: Contribution to journal › Article › peer-review
Interventions to facilitate the successful eruption of impacted maxillary incisor teeth due to the presence of a supernumerary: A systematic review and meta-analysis
Seehra, J., Mortaja, K., Wazwaz, F., Papageorgiou, S. N., Newton, J. T. & Cobourne, M. T., May 2023, In: American Journal of Orthodontics and Dentofacial Orthopedics. 163, 5, p. 594-608 15 p.Research output: Contribution to journal › Review article › peer-review
The quality and content of websites in the UK advertising aligner therapy: are standards being met?
Alsaqabi, F., Madadian, M. A., Pandis, N., Cobourne, M. T. & Seehra, J., 25 Apr 2023, (E-pub ahead of print) In: British Dental Journal.Research output: Contribution to journal › Article › peer-review
Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling
Qiu, T., Huteckova, B., Seppala, M., Cobourne, M., Chen, Z., hovorakova, M., Buchtova, M. & Tucker, A., 20 Mar 2023, (Accepted/In press) In: Development (Cambridge).Research output: Contribution to journal › Article › peer-review
Cellular mechanisms of reverse epithelial curvature in tissue morphogenesis
Wang, Y., Stonehouse-Smith, D., Cobourne, M. T., Green, J. B. A. & Seppala, M., 28 Nov 2022, In: Frontiers in Cell and Developmental Biology. 10, 1066399.Research output: Contribution to journal › Review article › peer-review
Reflections on the delivery of online postgraduate specialty membership examinations in orthodontics
Seehra, J., Eckhardt, C. E., Garrett, M. & Cobourne, M. T., 1 Sept 2022, In: British Dental Journal. 233, 6, p. 489 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Should we recommend early overjet reduction to prevent dental trauma?
Cobourne, M. T., DiBiase, A. T., Seehra, J. & Papageorgiou, S. N., 9 Sept 2022, In: British Dental Journal. 233, 5, p. 387-390 4 p.Research output: Contribution to journal › Article › peer-review
Study protocol for the management of impacted maxillary central incisors: a multicentre randomised clinical trial: the iMAC Trial
Seehra, J., DiBiase, A. T., Patel, S., Stephens, R., Littlewood, S. J., Spencer, R. J., Frawley, T., Benson, P. E., Ireland, A. J., Parvizi, F., Atack, N., Kidner, G., Wojewodka, G., Ward, C., Papageorgiou, S. N., Newton, J. T. & Cobourne, M. T., Dec 2022, In: Trials. 23, 1, 787.Research output: Contribution to journal › Article › peer-review
Do we get better outcomes from early treatment of Class III discrepancies?
DiBiase, A. T., Seehra, J., Papageorgiou, S. N. & Cobourne, M. T., 12 Aug 2022, In: British Dental Journal. 233, 3, p. 197-201 5 p.Research output: Contribution to journal › Article › peer-review
Mentolabial angle and aesthetics: a quantitative investigation of idealized and normative values
Naini, F. B., Cobourne, M. T., Garagiola, U., McDonald, F. & Wertheim, D., Dec 2017, In: Maxillofacial Plastic and Reconstructive Surgery. 39, 1, 4.Research output: Contribution to journal › Article › peer-review
Faculty clinical articles: a regular update for the oral healthcare team
Cobourne, M. T., Porter, S. R., Escudier, M. & Garrett, M., 8 Jul 2022, In: British Dental Journal. 233, 1, p. 52-54 3 p.Research output: Contribution to journal › Article › peer-review
An investigation into the reliability of a mobile app designed to assess orthodontic treatment need and severity
Nandra, S., Crawford, N., Burford, D., Pandis, N., Cobourne, M. T. & Seehra, J., 27 May 2022, In: British Dental Journal. 232, 10, p. 721-726 6 p.Research output: Contribution to journal › Article › peer-review
Dental anomalies in non-syndromic orofacial clefts: A clinical approach
das Neves, L. T., de Carvalho, I. M. M., Cobourne, M. T. & Gomide, M. R., Jul 2022, In: Oral Diseases. 28, 5, p. 1351-1368 18 p.Research output: Contribution to journal › Review article › peer-review
Salivary bacterial community profile in normal-weight and obese adolescent patients prior to orthodontic treatment with fixed appliances
Sharara, S. H., Cleaver, L. M., Saloom, H., Carpenter, G. H. & Cobourne, M. T., Nov 2022, In: Orthodontics and Craniofacial Research. 25, 4, p. 569-575 7 p.Research output: Contribution to journal › Article › peer-review
Peer Assessment Rating (PAR) scoring of cleft patients treated within a regional cleft centre in the United Kingdom
Furness, C., Veeroo, H., Kidner, G. & Cobourne, M. T., Mar 2022, In: Journal of orthodontics. 49, 1, p. 17-23 7 p.Research output: Contribution to journal › Article › peer-review
A cross-sectional study of exposure across social media platforms for the British Orthodontic Society retention awareness campaign: #HoldthatSmile
Lam, Y., Seehra, J., Abela, S. & Cobourne, M. T., 31 Mar 2022, In: Journal of orthodontics. 49, 1, p. 56-63 8 p.Research output: Contribution to journal › Article › peer-review
What are the differences in protective characteristics of orthodontic mouthguards? An in vitro study
Harrington, C., Minhas, G., Papageorgiou, S. N. & Cobourne, M. T., 25 Jan 2022, In: European journal of orthodontics. 44, 1, p. 95-100 6 p.Research output: Contribution to journal › Article › peer-review
Wearability and preference of mouthguard during sport in patients undergoing orthodontic treatment with fixed appliances: a randomized clinical trial
Kalra, A., Harrington, C., Minhas, G., Papageorgiou, S. N. & Cobourne, M. T., 25 Jan 2022, In: European journal of orthodontics. 44, 1, p. 101-109 9 p.Research output: Contribution to journal › Article › peer-review
Knowledge of evidence-based research methodology amongst orthodontic postgraduate residents in four universities: An international survey
Papageorgiou, S. N., Koletsi, D., Patcas, R., Seehra, J., Cobourne, M. T., Will, L. A. & Eliades, T., Mar 2022, In: International Orthodontics. 20, 1, 100609.Research output: Contribution to journal › Article › peer-review
What you read is what you get: Are orthodontic randomized clinical trials correctly titled?
Kane, G., Cobourne, M. T., Pandis, N. & Seehra, J., 21 Dec 2021, (E-pub ahead of print) In: American Journal of Orthodontics and Dentofacial Orthopedics.Research output: Contribution to journal › Article › peer-review
Are orthodontic randomised controlled trials justified with a citation of an appropriate systematic review?
Patel, K., Cobourne, M. T., Pandis, N. & Seehra, J., Dec 2021, In: Progress in Orthodontics. 22, 1, 48.Research output: Contribution to journal › Article › peer-review
Prolific authorship in orthodontic scientific publishing
Wong, C., Papageorgiou, S. N., Seehra, J. & Cobourne, M. T., 5 Dec 2021, (E-pub ahead of print) In: Orthodontics and Craniofacial Research.Research output: Contribution to journal › Article › peer-review
The perceptions of undertaking a higher degree alongside orthodontic speciality training: a cross-sectional survey of British Orthodontic Society members
Jopson, J. L., Haworth, J. A., Atack, N. E., Harrison, J. E., Cobourne, M. T., Cunningham, S. J. & Ireland, A. J., 23 Nov 2021, (E-pub ahead of print) In: British Dental Journal.Research output: Contribution to journal › Letter › peer-review
International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia
Savarirayan, R., Ireland, P., Irving, M., Thompson, D., Alves, I., Baratela, W. A. R., Betts, J., Bober, M. B., Boero, S., Briddell, J., Campbell, J., Campeau, P. M., Carl-Innig, P., Cheung, M. S., Cobourne, M., Cormier-Daire, V., Deladure-Molla, M., del Pino, M., Elphick, H. & Fano, V. & 35 others, Fauroux, B., Gibbins, J., Groves, M. L., Hagenäs, L., Hannon, T., Hoover-Fong, J., Kaisermann, M., Leiva-Gea, A., Llerena, J., Mackenzie, W., Martin, K., Mazzoleni, F., McDonnell, S., Meazzini, M. C., Milerad, J., Mohnike, K., Mortier, G. R., Offiah, A., Ozono, K., Phillips, J. A., Powell, S., Prasad, Y., Raggio, C., Rosselli, P., Rossiter, J., Selicorni, A., Sessa, M., Theroux, M., Thomas, M., Trespedi, L., Tunkel, D., Wallis, C., Wright, M., Yasui, N. & Fredwall, S. O., 26 Nov 2021, (E-pub ahead of print) In: Nature Reviews Endocrinology.Research output: Contribution to journal › Article › peer-review
Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog
Seppala, M., Thivichon-Prince, B., Xavier, G. M., Shaffie, N., Sangani, I., Birjandi, A. A., Rooney, J., Lau, J. N. S., Dhaliwal, R., Rossi, O., Riaz, M. A., Stonehouse-Smith, D., Wang, Y., Papageorgiou, S. N., Viriot, L. & Cobourne, M. T., Apr 2022, In: Journal of Dental Research. 101, 4, p. 365-482Research output: Contribution to journal › Article › peer-review
Duration of tooth alignment with fixed appliances: A systematic review and meta-analysis
Wazwaz, F., Seehra, J., Carpenter, G. H., Ireland, A. J., Papageorgiou, S. N. & Cobourne, M. T., Jan 2022, In: American Journal of Orthodontics and Dentofacial Orthopedics. 161, 1, p. 20-36 17 p.Research output: Contribution to journal › Article › peer-review
Development, implementation and feedback for an online speciality membership examination in orthodontics during the COVID-19 pandemic
Eckhardt, C. E., Seehra, J., Chadwick, S. M., Voerman, K., Landau, A., Ryan, F. S., Fleming, P. S., Garrett, M. & Cobourne, M. T., Oct 2021, In: British Dental Journal. 231, 8, p. 503-511 9 p.Research output: Contribution to journal › Article › peer-review
Not remotely interesting? Regulation and direct-to-consumer orthodontics in the United Kingdom
Deeming, G. & Cobourne, M. T., Sept 2021, In: Journal of orthodontics. 48, 3, p. 326-329 4 p.Research output: Contribution to journal › Comment/debate › peer-review
The impact of calcitriol on orthodontic tooth movement: A cumulative systematic review and meta-analysis
Al-Attar, A., Abid, M., Dziedzic, A., Al-Khatieeb, M. M., Seppala, M., Cobourne, M. T. & Abed, H., 1 Oct 2021, In: Applied Sciences (Switzerland). 11, 19, 8882.Research output: Contribution to journal › Article › peer-review
Orthodontic clinicians' attitudes and knowledge of dentogingival aesthetics: A cross-sectional survey of BOS members
Ajrash, E., DiBiase, A. T., Pandis, N., Cobourne, M. T. & Seehra, J., 11 Aug 2021, (E-pub ahead of print) In: Journal of Orthodontics.Research output: Contribution to journal › Article › peer-review
Are treatment effect assumptions in orthodontic studies overoptimistic?
Seehra, J., Stonehouse-Smith, D., Cobourne, M. T., Tsagris, M. & Pandis, N., 1 Oct 2021, In: European Journal of Orthodontics. 43, 5, p. 583-587 5 p.Research output: Contribution to journal › Article › peer-review
Product advertisements in orthodontic journals: Are they evidence-based?
Hameed, O., Pandis, N., Cobourne, M. T. & Seehra, J., Jul 2021, In: American Journal of Orthodontics and Dentofacial Orthopedics. 160, 1, p. 77-83 7 p.Research output: Contribution to journal › Article › peer-review
Methodological quality and risk of bias in orthodontic systematic reviews using AMSTAR and ROBIS
Hooper, E. J., Pandis, N., Cobourne, M. T. & Seehra, J., 16 Mar 2021, (E-pub ahead of print) In: European Journal of Orthodontics.Research output: Contribution to journal › Article › peer-review
The Journal of Orthodontics: A cross-sectional survey of British Orthodontic Society members
Jennings, R., Seehra, J. & Cobourne, M. T., Jun 2021, In: Journal of Orthodontics. 48, 2, p. 101-109 9 p.Research output: Contribution to journal › Article › peer-review
Reporting of the methodological quality of search strategies in orthodontic quantitative systematic reviews
AlMubarak, D., Pandis, N., Cobourne, M. T. & Seehra, J., 26 Dec 2020, In: European Journal of Orthodontics.Research output: Contribution to journal › Article › peer-review
Welcome to the new genomics: an introduction to the NHS Genomic Medicine Service for oral healthcare professionals
Cobourne, M. T., Irving, M. & Seller, A., Nov 2020, In: British Dental Journal. 229, 10, p. 682-686 5 p.Research output: Contribution to journal › Article › peer-review
Publication rate of abstracts from presentations at the British Orthodontic Conference 2009-2014
Al-Yatama, F., Pandis, N., Cobourne, M. T. & Seehra, J., 1 Dec 2020, In: Journal of orthodontics. 47, 4, p. 311-319 9 p.Research output: Contribution to journal › Article › peer-review
The impact of obesity on orthodontic treatment outcome in adolescents: a prospective clinical cohort study
Saloom, H. F., Boustan, R., Seehra, J., Papageorgiou, S. N., Carpenter, G. & Cobourne, M., May 2020, (E-pub ahead of print) In: European Journal of Orthodontics. p. cjaa032Research output: Contribution to journal › Article › peer-review
Palatal rugae morphology is associated with variation in tooth number
Armstrong, J., Seehra, J., Andiappan, M., Jones, A. G., Papageorgiou, S. N. & Cobourne, M. T., 1 Dec 2020, In: Scientific Reports. 10, 1, 19074.Research output: Contribution to journal › Article › peer-review
Author Correction: Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration (Nature Communications, (2020), 11, 1, (1994), 10.1038/s41467-020-15897-3)
Kim, Y., Lee, J., Seppala, M., Cobourne, M. T. & Kim, S. H., 5 May 2020, In: Nature Communications. 11, 1, 2275.Research output: Contribution to journal › Comment/debate › peer-review
Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration
Kim, Y., Lee, J., Seppala, M., Cobourne, M. T. & Kim, S. H., 24 Apr 2020, In: Nature Communications. 11, 1994.Research output: Contribution to journal › Article › peer-review
A comparison of conventional vs automated digital Peer Assessment Rating scoring using the Carestream 3600 scanner and CS Model+ software system: A randomized controlled trial
Luqmani, S., Jones, A., Andiappan, M. & Cobourne, M. T., 1 Feb 2020, In: American Journal of Orthodontics and Dentofacial Orthopedics. 157, 2, p. 148-155.e1Research output: Contribution to journal › Article › peer-review
The Opinion of Different Observer Groups About the Esthetic Impact and Need for Surgical Correction of Varying Submental Lengths
Naini, F. B., Laskin, D. M., Garagiola, U., Cobourne, M. T., McDonald, F. & Wertheim, D., Apr 2020, In: Journal of Oral and Maxillofacial Surgery. 78, 4, p. 630.e1-630.e9Research output: Contribution to journal › Article › peer-review
A cross-sectional cohort study of gingival crevicular fluid biomarkers in normal-weight and obese subjects during orthodontic treatment with fixed appliances
Saloom, H. F., Carpenter, G. H. & Cobourne, M. T., 1 Jan 2019, In: Angle Orthodontist. 89, 6, p. 930-935 6 p.Research output: Contribution to journal › Article › peer-review
Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature
Okuhara, S., Birjandi, A. A., Adel Al-Lami, H., Sagai, T., Amano, T., Shiroishi, T., Xavier, G. M., Liu, K. J., Cobourne, M. T. & Iseki, S., 2019, In: Development (Cambridge, England). 146, 21, dev180075.Research output: Contribution to journal › Article › peer-review
Research

Centre for Craniofacial & Regenerative Biology
Our research goes beyond the mouth. If we understand how the entire face and head forms, we can repair damage and regenerate cells. If we unravel the causes of diseases, we can treat patients successfully. If we solve these problems, our discoveries will improve health worldwide.
News
FoDOCS Professor elected as Senior Vice Dean of the FDS at the Royal College of Surgeons England
Professor Martyn Cobourne has been elected as the Senior Vice Dean at the Faculty of Dental Surgery, RCS

Professor Cobourne receives Dewel Award
Professor Martyn Cobourne and his co-workers are the recipients of the 2019 B. F. and Helen E. Dewel Award by the American Association of Orthodontists

Clinical evaluation of marketed and non-marketed orthodontic products: are researchers now ahead of the times? A meta-epidemiological study
Alhussain, A., Cobourne, M. T., Pandis, N. & Seehra, J., Dec 2023, In: Progress in Orthodontics. 24, 1, 32.Research output: Contribution to journal › Article › peer-review
Duration of canine retraction with fixed appliances: A systematic review and meta-analysis
Wazwaz, F., Seehra, J., Carpenter, G. H., Papageorgiou, S. N. & Cobourne, M. T., Feb 2023, In: American Journal of Orthodontics and Dentofacial Orthopedics. 163, 2, p. 154-172 19 p.Research output: Contribution to journal › Review article › peer-review
Accounting for clustering is still not routinely undertaken in orthodontic studies
Sudiskumar, N., Cobourne, M. T., Pandis, N. & Seehra, J., 1 Feb 2023, In: European journal of orthodontics. 45, 1, p. 45-50 6 p.Research output: Contribution to journal › Article › peer-review
The prevalence of and factors influencing statistical testing of baseline characteristics in randomized controlled trials published in high-impact orthodontic journals
Alduwaisan, A., Hirst, L., Cobourne, M. T., Pandis, N. & Seehra, J., Mar 2023, In: American Journal of Orthodontics and Dentofacial Orthopedics. 163, 3, p. e34-e83Research output: Contribution to journal › Article › peer-review
Does the quality of orthodontic studies influence their Altmetric Attention Score?
Alsaif, T., Pandis, N., Cobourne, M. T. & Seehra, J., 2023, In: Korean Journal of Orthodontics. 53, 5, p. 328-335 8 p.Research output: Contribution to journal › Article › peer-review
Periodontal outcomes associated with impacted maxillary central incisor and canine teeth following surgical exposure and orthodontic alignment: a systematic review and meta-analysis
Seehra, J., Alshammari, A., Wazwaz, F., Papageorgiou, S. N., Newton, J. T. & Cobourne, M. T., 1 Oct 2023, In: European journal of orthodontics. 45, 5, p. 584-598 15 p.Research output: Contribution to journal › Article › peer-review
Interventions to facilitate the successful eruption of impacted maxillary incisor teeth due to the presence of a supernumerary: A systematic review and meta-analysis
Seehra, J., Mortaja, K., Wazwaz, F., Papageorgiou, S. N., Newton, J. T. & Cobourne, M. T., May 2023, In: American Journal of Orthodontics and Dentofacial Orthopedics. 163, 5, p. 594-608 15 p.Research output: Contribution to journal › Review article › peer-review
The quality and content of websites in the UK advertising aligner therapy: are standards being met?
Alsaqabi, F., Madadian, M. A., Pandis, N., Cobourne, M. T. & Seehra, J., 25 Apr 2023, (E-pub ahead of print) In: British Dental Journal.Research output: Contribution to journal › Article › peer-review
Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling
Qiu, T., Huteckova, B., Seppala, M., Cobourne, M., Chen, Z., hovorakova, M., Buchtova, M. & Tucker, A., 20 Mar 2023, (Accepted/In press) In: Development (Cambridge).Research output: Contribution to journal › Article › peer-review
Cellular mechanisms of reverse epithelial curvature in tissue morphogenesis
Wang, Y., Stonehouse-Smith, D., Cobourne, M. T., Green, J. B. A. & Seppala, M., 28 Nov 2022, In: Frontiers in Cell and Developmental Biology. 10, 1066399.Research output: Contribution to journal › Review article › peer-review
Reflections on the delivery of online postgraduate specialty membership examinations in orthodontics
Seehra, J., Eckhardt, C. E., Garrett, M. & Cobourne, M. T., 1 Sept 2022, In: British Dental Journal. 233, 6, p. 489 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Should we recommend early overjet reduction to prevent dental trauma?
Cobourne, M. T., DiBiase, A. T., Seehra, J. & Papageorgiou, S. N., 9 Sept 2022, In: British Dental Journal. 233, 5, p. 387-390 4 p.Research output: Contribution to journal › Article › peer-review
Study protocol for the management of impacted maxillary central incisors: a multicentre randomised clinical trial: the iMAC Trial
Seehra, J., DiBiase, A. T., Patel, S., Stephens, R., Littlewood, S. J., Spencer, R. J., Frawley, T., Benson, P. E., Ireland, A. J., Parvizi, F., Atack, N., Kidner, G., Wojewodka, G., Ward, C., Papageorgiou, S. N., Newton, J. T. & Cobourne, M. T., Dec 2022, In: Trials. 23, 1, 787.Research output: Contribution to journal › Article › peer-review
Do we get better outcomes from early treatment of Class III discrepancies?
DiBiase, A. T., Seehra, J., Papageorgiou, S. N. & Cobourne, M. T., 12 Aug 2022, In: British Dental Journal. 233, 3, p. 197-201 5 p.Research output: Contribution to journal › Article › peer-review
Mentolabial angle and aesthetics: a quantitative investigation of idealized and normative values
Naini, F. B., Cobourne, M. T., Garagiola, U., McDonald, F. & Wertheim, D., Dec 2017, In: Maxillofacial Plastic and Reconstructive Surgery. 39, 1, 4.Research output: Contribution to journal › Article › peer-review
Faculty clinical articles: a regular update for the oral healthcare team
Cobourne, M. T., Porter, S. R., Escudier, M. & Garrett, M., 8 Jul 2022, In: British Dental Journal. 233, 1, p. 52-54 3 p.Research output: Contribution to journal › Article › peer-review
An investigation into the reliability of a mobile app designed to assess orthodontic treatment need and severity
Nandra, S., Crawford, N., Burford, D., Pandis, N., Cobourne, M. T. & Seehra, J., 27 May 2022, In: British Dental Journal. 232, 10, p. 721-726 6 p.Research output: Contribution to journal › Article › peer-review
Dental anomalies in non-syndromic orofacial clefts: A clinical approach
das Neves, L. T., de Carvalho, I. M. M., Cobourne, M. T. & Gomide, M. R., Jul 2022, In: Oral Diseases. 28, 5, p. 1351-1368 18 p.Research output: Contribution to journal › Review article › peer-review
Salivary bacterial community profile in normal-weight and obese adolescent patients prior to orthodontic treatment with fixed appliances
Sharara, S. H., Cleaver, L. M., Saloom, H., Carpenter, G. H. & Cobourne, M. T., Nov 2022, In: Orthodontics and Craniofacial Research. 25, 4, p. 569-575 7 p.Research output: Contribution to journal › Article › peer-review
Peer Assessment Rating (PAR) scoring of cleft patients treated within a regional cleft centre in the United Kingdom
Furness, C., Veeroo, H., Kidner, G. & Cobourne, M. T., Mar 2022, In: Journal of orthodontics. 49, 1, p. 17-23 7 p.Research output: Contribution to journal › Article › peer-review
A cross-sectional study of exposure across social media platforms for the British Orthodontic Society retention awareness campaign: #HoldthatSmile
Lam, Y., Seehra, J., Abela, S. & Cobourne, M. T., 31 Mar 2022, In: Journal of orthodontics. 49, 1, p. 56-63 8 p.Research output: Contribution to journal › Article › peer-review
What are the differences in protective characteristics of orthodontic mouthguards? An in vitro study
Harrington, C., Minhas, G., Papageorgiou, S. N. & Cobourne, M. T., 25 Jan 2022, In: European journal of orthodontics. 44, 1, p. 95-100 6 p.Research output: Contribution to journal › Article › peer-review
Wearability and preference of mouthguard during sport in patients undergoing orthodontic treatment with fixed appliances: a randomized clinical trial
Kalra, A., Harrington, C., Minhas, G., Papageorgiou, S. N. & Cobourne, M. T., 25 Jan 2022, In: European journal of orthodontics. 44, 1, p. 101-109 9 p.Research output: Contribution to journal › Article › peer-review
Knowledge of evidence-based research methodology amongst orthodontic postgraduate residents in four universities: An international survey
Papageorgiou, S. N., Koletsi, D., Patcas, R., Seehra, J., Cobourne, M. T., Will, L. A. & Eliades, T., Mar 2022, In: International Orthodontics. 20, 1, 100609.Research output: Contribution to journal › Article › peer-review
What you read is what you get: Are orthodontic randomized clinical trials correctly titled?
Kane, G., Cobourne, M. T., Pandis, N. & Seehra, J., 21 Dec 2021, (E-pub ahead of print) In: American Journal of Orthodontics and Dentofacial Orthopedics.Research output: Contribution to journal › Article › peer-review
Are orthodontic randomised controlled trials justified with a citation of an appropriate systematic review?
Patel, K., Cobourne, M. T., Pandis, N. & Seehra, J., Dec 2021, In: Progress in Orthodontics. 22, 1, 48.Research output: Contribution to journal › Article › peer-review
Prolific authorship in orthodontic scientific publishing
Wong, C., Papageorgiou, S. N., Seehra, J. & Cobourne, M. T., 5 Dec 2021, (E-pub ahead of print) In: Orthodontics and Craniofacial Research.Research output: Contribution to journal › Article › peer-review
The perceptions of undertaking a higher degree alongside orthodontic speciality training: a cross-sectional survey of British Orthodontic Society members
Jopson, J. L., Haworth, J. A., Atack, N. E., Harrison, J. E., Cobourne, M. T., Cunningham, S. J. & Ireland, A. J., 23 Nov 2021, (E-pub ahead of print) In: British Dental Journal.Research output: Contribution to journal › Letter › peer-review
International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia
Savarirayan, R., Ireland, P., Irving, M., Thompson, D., Alves, I., Baratela, W. A. R., Betts, J., Bober, M. B., Boero, S., Briddell, J., Campbell, J., Campeau, P. M., Carl-Innig, P., Cheung, M. S., Cobourne, M., Cormier-Daire, V., Deladure-Molla, M., del Pino, M., Elphick, H. & Fano, V. & 35 others, Fauroux, B., Gibbins, J., Groves, M. L., Hagenäs, L., Hannon, T., Hoover-Fong, J., Kaisermann, M., Leiva-Gea, A., Llerena, J., Mackenzie, W., Martin, K., Mazzoleni, F., McDonnell, S., Meazzini, M. C., Milerad, J., Mohnike, K., Mortier, G. R., Offiah, A., Ozono, K., Phillips, J. A., Powell, S., Prasad, Y., Raggio, C., Rosselli, P., Rossiter, J., Selicorni, A., Sessa, M., Theroux, M., Thomas, M., Trespedi, L., Tunkel, D., Wallis, C., Wright, M., Yasui, N. & Fredwall, S. O., 26 Nov 2021, (E-pub ahead of print) In: Nature Reviews Endocrinology.Research output: Contribution to journal › Article › peer-review
Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog
Seppala, M., Thivichon-Prince, B., Xavier, G. M., Shaffie, N., Sangani, I., Birjandi, A. A., Rooney, J., Lau, J. N. S., Dhaliwal, R., Rossi, O., Riaz, M. A., Stonehouse-Smith, D., Wang, Y., Papageorgiou, S. N., Viriot, L. & Cobourne, M. T., Apr 2022, In: Journal of Dental Research. 101, 4, p. 365-482Research output: Contribution to journal › Article › peer-review
Duration of tooth alignment with fixed appliances: A systematic review and meta-analysis
Wazwaz, F., Seehra, J., Carpenter, G. H., Ireland, A. J., Papageorgiou, S. N. & Cobourne, M. T., Jan 2022, In: American Journal of Orthodontics and Dentofacial Orthopedics. 161, 1, p. 20-36 17 p.Research output: Contribution to journal › Article › peer-review
Development, implementation and feedback for an online speciality membership examination in orthodontics during the COVID-19 pandemic
Eckhardt, C. E., Seehra, J., Chadwick, S. M., Voerman, K., Landau, A., Ryan, F. S., Fleming, P. S., Garrett, M. & Cobourne, M. T., Oct 2021, In: British Dental Journal. 231, 8, p. 503-511 9 p.Research output: Contribution to journal › Article › peer-review
Not remotely interesting? Regulation and direct-to-consumer orthodontics in the United Kingdom
Deeming, G. & Cobourne, M. T., Sept 2021, In: Journal of orthodontics. 48, 3, p. 326-329 4 p.Research output: Contribution to journal › Comment/debate › peer-review
The impact of calcitriol on orthodontic tooth movement: A cumulative systematic review and meta-analysis
Al-Attar, A., Abid, M., Dziedzic, A., Al-Khatieeb, M. M., Seppala, M., Cobourne, M. T. & Abed, H., 1 Oct 2021, In: Applied Sciences (Switzerland). 11, 19, 8882.Research output: Contribution to journal › Article › peer-review
Orthodontic clinicians' attitudes and knowledge of dentogingival aesthetics: A cross-sectional survey of BOS members
Ajrash, E., DiBiase, A. T., Pandis, N., Cobourne, M. T. & Seehra, J., 11 Aug 2021, (E-pub ahead of print) In: Journal of Orthodontics.Research output: Contribution to journal › Article › peer-review
Are treatment effect assumptions in orthodontic studies overoptimistic?
Seehra, J., Stonehouse-Smith, D., Cobourne, M. T., Tsagris, M. & Pandis, N., 1 Oct 2021, In: European Journal of Orthodontics. 43, 5, p. 583-587 5 p.Research output: Contribution to journal › Article › peer-review
Product advertisements in orthodontic journals: Are they evidence-based?
Hameed, O., Pandis, N., Cobourne, M. T. & Seehra, J., Jul 2021, In: American Journal of Orthodontics and Dentofacial Orthopedics. 160, 1, p. 77-83 7 p.Research output: Contribution to journal › Article › peer-review
Methodological quality and risk of bias in orthodontic systematic reviews using AMSTAR and ROBIS
Hooper, E. J., Pandis, N., Cobourne, M. T. & Seehra, J., 16 Mar 2021, (E-pub ahead of print) In: European Journal of Orthodontics.Research output: Contribution to journal › Article › peer-review
The Journal of Orthodontics: A cross-sectional survey of British Orthodontic Society members
Jennings, R., Seehra, J. & Cobourne, M. T., Jun 2021, In: Journal of Orthodontics. 48, 2, p. 101-109 9 p.Research output: Contribution to journal › Article › peer-review
Reporting of the methodological quality of search strategies in orthodontic quantitative systematic reviews
AlMubarak, D., Pandis, N., Cobourne, M. T. & Seehra, J., 26 Dec 2020, In: European Journal of Orthodontics.Research output: Contribution to journal › Article › peer-review
Welcome to the new genomics: an introduction to the NHS Genomic Medicine Service for oral healthcare professionals
Cobourne, M. T., Irving, M. & Seller, A., Nov 2020, In: British Dental Journal. 229, 10, p. 682-686 5 p.Research output: Contribution to journal › Article › peer-review
Publication rate of abstracts from presentations at the British Orthodontic Conference 2009-2014
Al-Yatama, F., Pandis, N., Cobourne, M. T. & Seehra, J., 1 Dec 2020, In: Journal of orthodontics. 47, 4, p. 311-319 9 p.Research output: Contribution to journal › Article › peer-review
The impact of obesity on orthodontic treatment outcome in adolescents: a prospective clinical cohort study
Saloom, H. F., Boustan, R., Seehra, J., Papageorgiou, S. N., Carpenter, G. & Cobourne, M., May 2020, (E-pub ahead of print) In: European Journal of Orthodontics. p. cjaa032Research output: Contribution to journal › Article › peer-review
Palatal rugae morphology is associated with variation in tooth number
Armstrong, J., Seehra, J., Andiappan, M., Jones, A. G., Papageorgiou, S. N. & Cobourne, M. T., 1 Dec 2020, In: Scientific Reports. 10, 1, 19074.Research output: Contribution to journal › Article › peer-review
Author Correction: Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration (Nature Communications, (2020), 11, 1, (1994), 10.1038/s41467-020-15897-3)
Kim, Y., Lee, J., Seppala, M., Cobourne, M. T. & Kim, S. H., 5 May 2020, In: Nature Communications. 11, 1, 2275.Research output: Contribution to journal › Comment/debate › peer-review
Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration
Kim, Y., Lee, J., Seppala, M., Cobourne, M. T. & Kim, S. H., 24 Apr 2020, In: Nature Communications. 11, 1994.Research output: Contribution to journal › Article › peer-review
A comparison of conventional vs automated digital Peer Assessment Rating scoring using the Carestream 3600 scanner and CS Model+ software system: A randomized controlled trial
Luqmani, S., Jones, A., Andiappan, M. & Cobourne, M. T., 1 Feb 2020, In: American Journal of Orthodontics and Dentofacial Orthopedics. 157, 2, p. 148-155.e1Research output: Contribution to journal › Article › peer-review
The Opinion of Different Observer Groups About the Esthetic Impact and Need for Surgical Correction of Varying Submental Lengths
Naini, F. B., Laskin, D. M., Garagiola, U., Cobourne, M. T., McDonald, F. & Wertheim, D., Apr 2020, In: Journal of Oral and Maxillofacial Surgery. 78, 4, p. 630.e1-630.e9Research output: Contribution to journal › Article › peer-review
A cross-sectional cohort study of gingival crevicular fluid biomarkers in normal-weight and obese subjects during orthodontic treatment with fixed appliances
Saloom, H. F., Carpenter, G. H. & Cobourne, M. T., 1 Jan 2019, In: Angle Orthodontist. 89, 6, p. 930-935 6 p.Research output: Contribution to journal › Article › peer-review
Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature
Okuhara, S., Birjandi, A. A., Adel Al-Lami, H., Sagai, T., Amano, T., Shiroishi, T., Xavier, G. M., Liu, K. J., Cobourne, M. T. & Iseki, S., 2019, In: Development (Cambridge, England). 146, 21, dev180075.Research output: Contribution to journal › Article › peer-review
Research

Centre for Craniofacial & Regenerative Biology
Our research goes beyond the mouth. If we understand how the entire face and head forms, we can repair damage and regenerate cells. If we unravel the causes of diseases, we can treat patients successfully. If we solve these problems, our discoveries will improve health worldwide.
News
FoDOCS Professor elected as Senior Vice Dean of the FDS at the Royal College of Surgeons England
Professor Martyn Cobourne has been elected as the Senior Vice Dean at the Faculty of Dental Surgery, RCS

Professor Cobourne receives Dewel Award
Professor Martyn Cobourne and his co-workers are the recipients of the 2019 B. F. and Helen E. Dewel Award by the American Association of Orthodontists
