Professor Tim Spector Academics Supervisors Professor of Genetic Epidemiology Head of Department, Department of Twin Research & Genetic Epidemiology. Contact details tim.spector@kcl.ac.uk
Microbiota composition is moderately associated with greenspace composition in a UK cohort of twins Bowyer, R., Twohig-Bennett, C., Coombes, E., Wells, P., Spector, T., Jones, A. & Steves, C., 20 Mar 2022, In: Science of the Total Environment. 813, 152321. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.scitotenv.2021.152321 Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait Venkataraman, T., Valencia, C., Mangino, M., Morgenlander, W., Clipman, S. J., Liechti, T., Valencia, A., Christofidou, P., Spector, T., Roederer, M., Duggal, P. & Larman, H. B., 11 Jan 2022, In: Immunity. 55, 1, p. 174-184.e5 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.immuni.2021.12.004 Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels Hysi, P. G., Mangino, M., Christofidou, P., Falchi, M., Karoly, E. D., NIHR Bioresource Investigators, NIHR. B. I., Mohney, R. P., Valdes, A. M., Spector, T. D. & Menni, C., 11 Jan 2022, (E-pub ahead of print) In: Metabolites. 12, 1, p. e61 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/metabo12010061 Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study Antonelli, M., Penfold, R. S., Merino, J., Sudre, C. H., Molteni, E., Berry, S., Canas, L. S., Graham, M. S., Klaser, K., Modat, M., Murray, B., Kerfoot, E., Chen, L., Deng, J., Österdahl, M. F., Cheetham, N. J., Drew, D. A., Nguyen, L. H., Pujol, J. C., Hu, C. & 10 others, Selvachandran, S., Polidori, L., May, A., Wolf, J., Chan, A. T., Hammers, A., Duncan, E. L., Spector, T. D., Ourselin, S. & Steves, C. J., Jan 2022, In: The Lancet infectious diseases. 22, 1, p. 43-55 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/S1473-3099(21)00460-6 Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function MuTHER Consortium, 2022, (Accepted/In press) In: Nature genetics. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41588-021-00969-x N-glycosylation of immunoglobulin G predicts incident hypertension Kifer, D., Louca, P., Cvetko, A., Deriš, H., Cindrić, A., Grallert, H., Peters, A., Polašek, O., Gornik, O., Mangino, M., Spector, T. D., Valdes, A. M., Padmanabhan, S., Gieger, C., Lauc, G. & Menni, C., 1 Dec 2021, In: Journal of hypertension. 39, 12, p. 2527-2533 7 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1097/HJH.0000000000002963 A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans Bejar, C. A., Goyal, S., Afzal, S., Mangino, M., Zhou, A., van der Most, P. J., Bao, Y., Gupta, V., Smart, M. C., Walia, G. K., Verweij, N., Power, C., Prabhakaran, D., Singh, J. R., Mehra, N. K., Wander, G. S., Ralhan, S., Kinra, S., Kumari, M., de Borst, M. H. & 5 others, Hyppönen, E., Spector, T. D., Nordestgaard, B. G., Blackett, P. R. & Sanghera, D. K., Dec 2021, In: Nutrition Journal. 20, 1, 71. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1186/s12937-021-00725-1 A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids Jhun, M. A., Mendelson, M., Wilson, R., Gondalia, R., Joehanes, R., Salfati, E., Zhao, X., Braun, K. V. E., Do, A. N., Hedman, Å. K., Zhang, T., Carnero-Montoro, E., Shen, J., Bartz, T. M., Brody, J. A., Montasser, M. E., O’Connell, J. R., Yao, C., Xia, R., Boerwinkle, E. & 44 others, Grove, M., Guan, W., Liliane, P., Singmann, P., Müller-Nurasyid, M., Meitinger, T., Gieger, C., Peters, A., Zhao, W., Ware, E. B., Smith, J. A., Dhana, K., van Meurs, J., Uitterlinden, A., Ikram, M. A., Ghanbari, M., Zhi, D., Gustafsson, S., Lind, L., Li, S., Sun, D., Spector, T. D., Chen, Y. D. I., Damcott, C., Shuldiner, A. R., Absher, D. M., Horvath, S., Tsao, P. S., Kardia, S., Psaty, B. M., Sotoodehnia, N., Bell, J. T., Ingelsson, E., Chen, W., Dehghan, A., Arnett, D. K., Waldenberger, M., Hou, L., Whitsel, E. A., Baccarelli, A., Levy, D., Fornage, M., Irvin, M. R. & Assimes, T. L., Dec 2021, In: Nature Communications. 12, 1, 3987. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-021-23899-y Association of social distancing and face mask use with risk of COVID-19 Kwon, S., Joshi, A. D., Lo, C. H., Drew, D. A., Nguyen, L. H., Guo, C. G., Ma, W., Mehta, R. S., Shebl, F. M., Warner, E. T., Astley, C. M., Merino, J., Murray, B., Wolf, J., Ourselin, S., Steves, C. J., Spector, T. D., Hart, J. E., Song, M., VoPham, T. & 1 others, Chan, A. T., Dec 2021, In: Nature Communications. 12, 1, 3737. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-021-24115-7 Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes AMP-T2D-GENES Consortia, Dec 2021, In: Nature Communications. 12, 1, 3505. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-021-23556-4 View all publications
8 September 2021 Eating a plant rich diet reduces risk of developing COVID-19 People who eat a high quality, gut friendly diet are less likely to develop COVID-19 or become…