Dr Rocio Sancho Academics Supervisors Group Leader / Senior Lecturer Research subject areas Diabetes Immunology Contact details rocio.sancho@kcl.ac.uk +44 (0) 20 7188 5604 @LabSancho
Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids Pedraza-Arevalo, S., Cujba, A. M., Alvarez-Fallas, M. E. & Sancho, R., 16 Sep 2022, In: STAR Protocols. 3, 3, p. 101656 1 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.xpro.2022.101656 An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function Cujba, A. M., Alvarez-Fallas, M. E., Pedraza-Arevalo, S., Laddach, A., Shepherd, M. H., Hattersley, A. T., Watt, F. M. & Sancho, R., 1 Mar 2022, In: Cell Reports. 38, 9, 110425. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.celrep.2022.110425 An HNF1a truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonising HNF1b function Sancho, R., Cujba, A-M., Alvarez Fallas, M., Pedraza Arevalo, S., Laddach, A., Shepherd, M. H., Hattersley, A. T. & Watt, F., 2 Feb 2022, (Accepted/In press) In: Cell Reports. Research output: Contribution to journal › Article › peer-review Stem/progenitor cells in normal physiology and disease of the pancreas Alvarez Fallas, M. E., Pedraza-Arevalo, S., Cujba, A. M., Manea, T., Lambert, C., Morrugares, R. & Sancho, R., 1 Dec 2021, In: Molecular and Cellular Endocrinology. 538, 111459. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.mce.2021.111459 Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas Gribben, C., Lambert, C., Messal, H. A., Hubber, E., Rackham, C., Evans, I., Heimberg, H., Jones, P., Sancho, R. & Behrens, A., 4 Nov 2021, In: Cell Stem Cell. 28, 11, p. 2000-2008.e4 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.stem.2021.08.003 The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease Bornstein, S. R., Guan, K., Brunβen, C., Mueller, G., Kamvissi-Lorenz, V., Lechler, R., Trembath, R., Mayr, M., Poston, L., Sancho, R., Ahmed, S., Alfar, E., Aljani, B., Alves, T. C., Amiel, S., Andoniadou, C. L., Bandral, M., Belavgeni, A., Berger, I., Birkenfeld, A., & 74 othersBonifacio, E., Chavakis, T., Chawla, P., Choudhary, P., Cujba, A. M., Delgadillo Silva, L. F., Demcollari, T., Drotar, D. M., Duin, S., El-Agroudy, N. N., El-Armouche, A., Eugster, A., Gado, M., Gavalas, A., Gelinsky, M., Guirgus, M., Hansen, S., Hanton, E., Hasse, M., Henneicke, H., Heller, C., Hempel, H., Hogstrand, C., Hopkins, D., Jarc, L., Jones, P. M., Kamel, M., Kämmerer, S., King, A. J. F., Kurzbach, A., Lambert, C., Latunde-Dada, Y., Lieberam, I., Liers, J., Li, J. W., Linkermann, A., Locke, S., Ludwig, B., Manea, T., Maremonti, F., Marinicova, Z., McGowan, B. M., Mickunas, M., Mingrone, G., Mohanraj, K., Morawietz, H., Ninov, N., Peakman, M., Persaud, S. J., Pietzsch, J., Cachorro, E., Pullen, T. J., Pyrina, I., Rubino, F., Santambrogio, A., Schepp, F., Schlinkert, P., Scriba, L. D., Siow, R., Solimena, M., Spagnoli, F. M., Speier, S., Stavridou, A., Steenblock, C., Strano, A., Taylor, P., Tiepner, A., Tonnus, W., Tree, T., Watt, F., Werdermann, M., Wilson, M., Yusuf, N. & Ziegler, C. G., 1 Mar 2021, In: Hormone and Metabolic Research. 53, 3, p. 204-206 3 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1055/a-1377-6583 Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors Segal, J. M., Kent, D. H., Wesche, D., Ng, S. S., Quake, S., Serra, M., Nakauchi, H., Rashid, S. T., King, A., Oules, B., Kar, G., Emerton, G., Blackford, S., Darmanis, S., Miquel, R., Luong, T. V., Yamamoto, R., Bonham, A., Jassem, W., Heaton, N., & 3 othersVigilante, A., Sancho, R. & Teichmann, S. A., 24 Jun 2019, (Accepted/In press) In: Nature Communications. 10, 1, 14 p., 3350. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-019-11266-x LUBAC determines chemotherapy resistance in squamous cell lung cancer Ruiz, E. J., Diefenbacher, M. E., Nelson, J. K., Sancho, R., Pucci, F., Chakraborty, A., Moreno, P., Annibaldi, A., Liccardi, G., Encheva, V., Mitter, R., Rosenfeldt, M., Snijders, A. P., Meier, P., Calzado, M. A. & Behrens, A., 4 Feb 2019, In: The Journal of experimental medicine. 216, 2, p. 450-465 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1084/jem.20180742 Lung based engineered micro-pancreas sustains human beta cell survival and functionality Goldman, O., Puchinsky, D., Durlacher, K., Sancho, R., Ludwig, B., Kugelmeier, P., Heller, C., Kunicher, N., Bornstein, S. R. & Treves, A. J., 1 Jan 2019, In: Hormone and Metabolic Research. 51, 12, p. 805-811 7 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1055/a-1041-3305 Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease? Bornstein, S. R., Steenblock, C., Chrousos, G. P., Schally, A. V., Beuschlein, F., Kline, G., Krone, N. P., Licinio, J., Wong, M. L., Ullmann, E., Ruiz-Babot, G., Boehm, B. O., Behrens, A., Brennand, A., Santambrogio, A., Berger, I., Werdermann, M., Sancho, R., Linkermann, A., Lenders, J. W., & 2 othersEisenhofer, G. & Andoniadou, C. L., 21 Sep 2018, In: Molecular Psychiatry. 24, p. 2-9 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41380-018-0244-9 View all publications
2 March 2022 Study unravels new disease mechanism for monogenic diabetes Article in Cell Reports reveals an unknown developmental defect that could happen in MODY3 patients…