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Roland Zahn

Professor Roland Zahn

Professor of Mood Disorders & Cognitive Neuroscience

Research interests

  • Psychiatry

Contact details

Biography

Roland Zahn studied medicine in Heidelberg and Aachen and received his research MD in cognitive neurology from the University of Aachen (RWTH) before completing his clinical training in psychiatry and psychotherapy at Freiburg University Hospital in Germany.

Funded by a fellowship from the German National Academy of Sciences, he investigated the neural basis of social knowledge and moral emotions such as guilt at the US National Institutes of Health.

At the University of Manchester his research on mood disorders and frontotemporal dementia was supported by a Stepping Stones and MRC Clinician Scientist Fellowship and focused on elucidating the neural bases of self-blame in mood disorders.

In Manchester, he also trained in old age psychiatry and subsequently worked as an Honorary Consultant Psychiatrist in specialist cognitive assessment and affective disorders services.

He has joined the Centre for Affective Disorders at the Institute of Psychiatry, Psychology & Neuroscience at King’s College London in 2013 as a Senior Clinical Lecturer and since 2022, as a Clinical Professor of Mood Disorders & Cognitive Neuroscience. In 2025, he has stepped up as the joint director of the Centre. From 2021, he has been the Acting Deputy Head of the Department of Psychological Medicine and the Deputy Theme Lead for Mood Disorders within the NIHR Maudsley Biomedical Research Centre for Mental Health.

As an Honorary Consultant Psychiatrist, his focus has been on mood disorders at the National Service for Affective Disorders, where he leads the Vagus Nerve Stimulation clinic within the Maudsley Advanced Treatment service, as well as in primary care settings in South London and as well as running a specialist mood clinic within the King’s Student Counselling and Mental Health services. 

Research Interests

Based on his previous work on the role of the right anterior temporal lobe in representing and differentiating social concepts and the role of the subgenual region in social agency detection and affiliative value underpinning blame biases as reflected in the phenomenology of affective disorders, he is developing prediction models for prognosis and personalisation of treatments and care pathways (precision psychiatry and decision support systems) using neurocognitive markers.

He further seeks to develop novel blended digital and neuromodulation treatments aimed at cognitive-anatomical correlates of self-blaming biases and loss of affiliative interest, which are key symptoms of depression.

His long-term goal is to collaborate with colleagues to advance our understanding of mood disorders with a comprehensive and integrated translational cognitive neuroscience model which bridges the phenomenology of symptoms with psychological, neural and molecular mechanisms. 

Research Groups

Professor Roland Zahn is Joint Director of the Centre for Affective Disorders

Expertise and Public Engagement

Roland Zahn's research on the neurocognitive bases of self-blame and mood disorders was featured in several media interviews and documentary films, such as:

Teaching

Roland Zahn leads the Understanding Affective Disorders module on the MSc in Affective Disorders.

Additional Information 

Roland Zahn is an honorary principal investigator with Jorge Moll's lab at the D'Or Institute for Research & Education in Rio de Janeiro, Brazil  

    Research

    brain trees
    Centre for Affective Disorders

    The Centre for Affective Disorders focuses on mood and anxiety disorders, common disorders which cause great suffering for many people.

    antidepressants
    Antidepressant Advisor Study (ADeSS)

    For many people with depression, the antidepressants most usually prescribed by GPs are only somewhat helpful.

    Project status: Ongoing

    Therapy-Session
    ADeSS study 3: fMRI study to predict treatment response in patients with depression

    The aim of this study is to find better ways to predict how well a treatment works for a particular person with depression.

    Project status: Ongoing

    20181214, Virtual reality headset in dental psychology
    A virtual reality study of depression

    The aim of this study is to find better ways to predict how well a treatment works for a particular person with depression.

    Project status: Ongoing

    depression small
    Longing is Good - proof-of-concept for a novel psychological intervention to tackle self-blaming emotions

    The purpose of this project is to inform a new psychological intervention to alleviate self-blaming emotions in major depressive disorder.

    Project status: Ongoing

    NESPRED-logo_final
    Neurocognitive signatures predicting risk of recurrent depression (NESPRED) study

    After recovering from depression, it is currently difficult to advise on the risk of future recurring episodes. The aim of this study is to find better ways to predict the risk of future depressive episodes for a particular person

    vrlab_banner-image_children_placeholder
    IoPPN Virtual Reality Lab

    The IoPPN Virtual Reality Research Lab (VR Lab) is a world-leading multidisciplinary group dedicated to VR based research, assessment and treatments to improve mental health, enhance well-being and promote resilience.

    News

    The finger of blame in depression and the brain

    Professor Roland Zahn delivered the eighth inaugural lecture of the 2022/23 IoPPN Inaugural Lecture Series, entitled 'The finger of blame in depression and...

    Roland Zahn inaugural

    Using neurofeedback as a means of treating feelings of self-blame in depression

    New research has suggested that using neurofeedback to address self-blame in people experiencing non-anxious major depressive disorder (MDD) can help to...

    feedback_hero

    Features

    IoPPN Inaugural Lectures: 2022-2023

    Inaugural lectures are given by newly arrived or promoted professors, who use the opportunity to introduce themselves, to present an overview of their own...

    Brain in pastel colours

      Research

      brain trees
      Centre for Affective Disorders

      The Centre for Affective Disorders focuses on mood and anxiety disorders, common disorders which cause great suffering for many people.

      antidepressants
      Antidepressant Advisor Study (ADeSS)

      For many people with depression, the antidepressants most usually prescribed by GPs are only somewhat helpful.

      Project status: Ongoing

      Therapy-Session
      ADeSS study 3: fMRI study to predict treatment response in patients with depression

      The aim of this study is to find better ways to predict how well a treatment works for a particular person with depression.

      Project status: Ongoing

      20181214, Virtual reality headset in dental psychology
      A virtual reality study of depression

      The aim of this study is to find better ways to predict how well a treatment works for a particular person with depression.

      Project status: Ongoing

      depression small
      Longing is Good - proof-of-concept for a novel psychological intervention to tackle self-blaming emotions

      The purpose of this project is to inform a new psychological intervention to alleviate self-blaming emotions in major depressive disorder.

      Project status: Ongoing

      NESPRED-logo_final
      Neurocognitive signatures predicting risk of recurrent depression (NESPRED) study

      After recovering from depression, it is currently difficult to advise on the risk of future recurring episodes. The aim of this study is to find better ways to predict the risk of future depressive episodes for a particular person

      vrlab_banner-image_children_placeholder
      IoPPN Virtual Reality Lab

      The IoPPN Virtual Reality Research Lab (VR Lab) is a world-leading multidisciplinary group dedicated to VR based research, assessment and treatments to improve mental health, enhance well-being and promote resilience.

      News

      The finger of blame in depression and the brain

      Professor Roland Zahn delivered the eighth inaugural lecture of the 2022/23 IoPPN Inaugural Lecture Series, entitled 'The finger of blame in depression and...

      Roland Zahn inaugural

      Using neurofeedback as a means of treating feelings of self-blame in depression

      New research has suggested that using neurofeedback to address self-blame in people experiencing non-anxious major depressive disorder (MDD) can help to...

      feedback_hero

      Features

      IoPPN Inaugural Lectures: 2022-2023

      Inaugural lectures are given by newly arrived or promoted professors, who use the opportunity to introduce themselves, to present an overview of their own...

      Brain in pastel colours