Sabrina Hossain
PhD Student
Biography
Sabrina obtained her MSci Biochemistry at the University of Birmingham in 2019. For her master’s project, she worked in Dr Timothy Knowles laboratory investigating the structure of the bacterial membrane protein DsbD in its natural lipid environment, using styrene maleic acid lipid particles (SMALPs). In summer 2021, Sabrina joined the Biological Physics Across Scales Centre for Doctoral Training (BiPAS CDT) where she will be undertaking her project co-supervised by Dr Argyris Politis and Dr Manuel Müller. Sabrina’s project will be probing the conformational dynamics that underpin function in intrinsically disordered proteins including p53 using hydrogen-deuterium exchange mass spectrometry (HDX-MS) visualised with data-driven modelling.
Research interests
- Structural biology of proteins
- Protein biochemistry and mechanisms of action
- Translational research for drug discovery
- Data-driven modelling
PhD supervisors
Research
Müller Group
Research in the Müller lab focuses on using synthetic protein chemistry to elucidate how proteins are controlled by post-translational modifications.
Borysik Group
The Borysik Group focuses on Biomolecular Mass Spectrometry.
Research
Müller Group
Research in the Müller lab focuses on using synthetic protein chemistry to elucidate how proteins are controlled by post-translational modifications.
Borysik Group
The Borysik Group focuses on Biomolecular Mass Spectrometry.