Dr. Saeed Shoaie is the group leader of Translational Systems Biology at CHMI. He is a BBSRC and EPSRC UKRI fellow since 2018 and the deputy lead of master program for microbiome at KCL.
He has received his Msc and PhD degrees in Innovative and Sustainable Chemical Engineering and in Systems and Synthetic Biology of Host-Microbiome Interactions, from Prof. Jens Nielsen Systems Biology lab at Chalmers University of Technology, Sweden. He worked as a researcher at Novo Nordisk A/S and Steno diabetic center in Denmark, and Science for life laboratory in Sweden, before he appointed as a Lecturer in Systems and Synthetic biology at King’s College London.
His research activities from one side focus on analyzing multi-omics data in different cohort studies and aim to identify biomarkers and novel treatment strategies for human diseases. From the other side his activities include the generation of genome-scale metabolic models for host and microbiome, using these models as a scaffold to analysis of omics data with the objective to elucidate the host-microbiome interactions in different human disorders.
His lab develops systems biology and bioinformatics tools that is a necessary component to perform integrated analysis and apply them in personalized medicine research area. In one of his work he developed a mathematical platform that makes it possible to predict how different patients will respond to a modified diet, depending on how each individual gut microbiome is composed. This study has been published in Cell Metabolism and covered by more than 100 journals around the world. Now his research group improving the approach to design the personalized diet regime based on the individual gut microbiome for early prevention of metabolic disorders. These studies will assist to determination of what could take months of try and error. This leads to synthesize the modern tools and modern capacities with ancient privilege of the doctor-patient relationship to provide personalized care.