Sasi Conte Professor Sasi Conte Academics Professor of Structural Biology Head of Randall Centre. Director of the Centre for Biomolecular Spectroscopy. Contact details sasi.conte@kcl.ac.uk +44 (0) 20 7848 6194
Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition Conte, M. R., 2023, (Accepted/In press) In: Scientific Reports. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-023-27375-z Allosteric Regulation of the Soluble Epoxide Hydrolase by Nitro Fatty Acids: a Combined Experimental and Computational Approach: Allosteric regulation of hsEH by nitro fatty acids Qiu, Q., Abis, G., Mattingly-Peck, F., Lynham, S., Fraternali, F. & Conte, M. R., 15 Sep 2022, In: Journal of Molecular Biology. 434, 17, 167600. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jmb.2022.167600 Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1 Conte, M. R., 11 Jan 2022, In: Nucleic Acids Research. 50, 1, p. 522-535 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/nar/gkab1216 A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation Charles, R. L., Abis, G., Fernandez, B. F., Guttzeit, S., Buccafusca, R., Conte, M. R. & Eaton, P., Oct 2021, In: Redox Biology. 46, 102107. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.redox.2021.102107 LARP6C orchestrates posttranscriptional reprogramming of gene expression during hydration to promote pollen tube guidance Billey, E., Hafidh, S., Cruz-gallardo, I., Litholdo, C. G., Jean, V., Carpentier, M-C., Picart, C., Kumar, V., Kulichova, K., Maréchal, E., Honys, D., Conte, M. R., Deragon, J-M. & Bousquet-Antonelli, C., Aug 2021, In: Plant Cell. 33, 8, p. 2637-2661 25 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/plcell/koab131 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α-TAB1 Complexes Nichols, C., Ng, J., Keshu, A., Kelly, G., Conte, M. R., Marber, M. S., Fraternali, F. & De Nicola, G. F., 23 Jul 2020, In: Journal of Medicinal Chemistry. 63, 14, p. 7559-7568 10 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acs.jmedchem.0c00403 Maternal Larp6 controls oocyte development, chorion formation and elevation Hau, H. T. A., Ogundele, O., Hibbert, A. H., Monfries, C. A. L., Exelby, K., Wood, N. J., Nevarez-Mejia, J., Carbajal, M. A., Fleck, R. A., Dermit, M., Mardakheh, F. K., Williams-Ward, V. C., Pipalia, T. G., Conte, M. R. & Hughes, S. M., 13 Feb 2020, (E-pub ahead of print) In: Development (Cambridge, England). 147, 4, dev187385. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1242/dev.187385, https://doi.org/10.1242/dev.187385 Structural dynamics in the La-module of La-related proteins Conte, M., Feb 2020, (Accepted/In press) In: Rna Biology. Research output: Contribution to journal › Article › peer-review Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase Abis, G., Pacheco-Gómez, R., Bui, T. T. T. & Conte, M. R., 3 Dec 2019, In: Analytical Chemistry. 91, 23, p. 14865-14872 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acs.analchem.9b01847 The La-related proteins: Structures and interactions of a versatile superfamily of RNA binding proteins Conte, M. R., 3 Dec 2019, (E-pub ahead of print) In: Rna Biology. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1080/15476286.2019.1695712 View all publications