Candida-induced metabolic reprogramming of epithelial cells Candida albicans is a very interesting fungus that can be both a commensal and pathogenic organism, depending on the mucosal environmental conditions (immune status, etc). In the oral cavity, epithelial cells come into direct contact with the fungus and its recognition drives activation of signalling pathways and immune responses in the epithelium. These responses induce a series of changes in epithelial cells that impact on their interaction with the fungus. We apply molecular and cellular biology techniques, as well as multi-omic data sets, to investigate the ability of C. albicans to drive changes in cellular metabolism that boost epithelial immune responses. Further, we investigate how these shifts potentially initiate the development of long-term responses (e.g. innate immune memory) by epithelial cells in response to C. albicans.