Genomics and Epigenomics

The analysis of genomics data has revolutionized the way we approach research, opening new paths to understanding very complicated biological mechanisms, and life itself. At the HAB we offer a wide range of cutting-edge data analysis services to process, analyse, visualise and interpret genomic data. We can assist with Whole Genome and Whole Exome Sequencing data, Genome-Wide Association Studies, Comparative and Structural Comparative Genomics. We can also provide expertise in epigenomics analyses including Chromatin Accessibility Profiling, DNA Methylation Profiling and Histone Modification analysis.

Transcriptomics and spatial transcriptomics

At the HAB, we provide a wide variety of transcriptomic data analysis services that can be tailored to meet the needs of researchers with diverse biological questions. Our team can support analysis of bulk and single-cell RNA sequencing, Spatial Transcriptomics Assays and Single-Cell Spatial Transcriptomics as well as 3D Spatial Transcriptomics. We offer guidance in experimental design, analysis and provide expertise in selecting appropriate analysis methods, offering customized solutions to meet the specific needs of researchers.

Proteomics

Proteomics is a vital component of biological research, allowing us to understand the complex molecular processes that drive cellular functions. Proteomics analysis provides valuable insights into the composition, function, and interaction of proteins within a biological system. At the HAB, we support proteomics research by providing a range of analysis services, including protein identification and quantification, post-translational modification analysis, protein-protein interaction analysis, and functional analysis. Additionally, we can develop customized workflows and pipelines to suit the specific needs of research projects and provide support in analyzing and interpreting proteomics data.

Image analysis

Image analysis is an essential tool in biological research as it allows us to extract quantitative information from images of biological samples. Image analysis is widely used in fields such as cell biology, neuroscience, and genetics but can be applied to many other research projects. At the HAB we can help with every step of image analysis, from image preprocessing and segmentation to feature extraction, and data analysis. Machine learning or deep learning techniques may be used to automate some aspects of the analysis and to develop predictive models based on imaging data.

Metabolomics and microbiome

The microbiome is increasingly recognized as an important contributor to host health and disease, with studies showing that disruptions to the microbiome can lead to various health problems. Metagenomics, the study of genetic material from complex microbial communities, is being increasingly used in clinical and public health research to identify pathogenic microorganisms and to study the human microbiome and its role in health and disease. At the HAB we support all the steps involved in the analysis and interpretion of large amounts of metagenomic data, including quality control, assembly, annotation, taxonomic classification, and functional analysis of metagenomic sequences.

Bioinformatics support

At the HAB we are proud to offer a research-oriented bioinformatics core where senior bioinformaticians provide the experience and expertise a researcher could need to complement and collaborate with their own team's specific need. We are able to support scientists during different stages of a research projects, from the experimental design and grant writing to data processing, data analysis and data management. Our goal is to work together with your team to provide you with the support and guidance you need to achieve your research goals. A steering committee with a representative of each school of the Faculty of Life Science and Medicine is going to assist in the choice of which project to support in order to make sure we provide a fair service across the Faculty.

• HAB Bioinformatics support

Training programme

We offer a range of workshops and training programs designed to cater to different levels of expertise, from beginner to advanced. The fees for these workshops vary depending on the participant's career level and affiliation. In addition, the HAB is closely associated with an MSc programme in Applied Bioinformatics, equipping students to pursue careers in research, industry or academia.

• Hub for Applied Bioinformatics Training

Internal Engagement activities

The Hub's internal engagement activity is an important part of our mission to foster a collaborative and interdisciplinary research environment. We organize seminars, data clubs, and journal clubs around research workstreams and different applications, giving students the opportunity to share their knowledge and learn from one another. 

• HAB Internal Engagement