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Welcome to the Hub for Applied Bioinformatics @KCL, a place where big data are transformed into valuable knowledge that can drive scientific breakthroughs in the fields of life sciences and medicine.

Our mission is to create a collaborative environment where ideas and expertise can be shared freely, leading to greater productivity and innovation in the field of bioinformatics. Whether you're a student, a research associate or a PI, HAB is the perfect place to learn more about bioinformatics and its application and to getting research done. At the HAB you'll be able to apply for bioinformatics support, attend seminars and data club designed around research workstreams, and attend training sessions taught by experts in the fieds. At HAB, we understand the value of collaboration and networking, which is why we offer the unique opportunity to book desks in our bioinformatics space. This allows you to work alongside other researchers who are also tackling similar bioinformatics challenges. Navigate to our website to learn more and why not join our Slack community.

People

Flavia Flaviani

Senior Bioinformatician

Xin Yi Ng

PhD Student

Operations Assistant

Michelle Simon

Senior Bioinformatician

Rachel  Tribe

Vice Dean (Research & Impact)

Themes

genomics_and_genetics_big
Genomics and Epigenomics

The analysis of genomics data has revolutionized the way we approach research, opening new paths to understanding very complicated biological mechanisms, and life itself. At the HAB we offer a wide range of cutting-edge data analysis services to process, analyse, visualise and interpret genomic data. We can assist with Whole Genome and Whole Exome Sequencing data, Genome-Wide Association Studies, Comparative and Structural Comparative Genomics. We can also provide expertise in epigenomics analyses including Chromatin Accessibility Profiling, DNA Methylation Profiling and Histone Modification analysis.

    transcriptomic_and_spatial_big
    Transcriptomics and spatial transcriptomics

    At the HAB, we provide a wide variety of transcriptomic data analysis services that can be tailored to meet the needs of researchers with diverse biological questions. Our team can support analysis of bulk and single-cell RNA sequencing, Spatial Transcriptomics Assays and Single-Cell Spatial Transcriptomics as well as 3D Spatial Transcriptomics. We offer guidance in experimental design, analysis and provide expertise in selecting appropriate analysis methods, offering customized solutions to meet the specific needs of researchers.

      proteomics_big
      Proteomics

      Proteomics is a vital component of biological research, allowing us to understand the complex molecular processes that drive cellular functions. Proteomics analysis provides valuable insights into the composition, function, and interaction of proteins within a biological system. At the HAB, we support proteomics research by providing a range of analysis services, including protein identification and quantification, post-translational modification analysis, protein-protein interaction analysis, and functional analysis. Additionally, we can develop customized workflows and pipelines to suit the specific needs of research projects and provide support in analyzing and interpreting proteomics data.

        image_analysis
        Image analysis

        Image analysis is an essential tool in biological research as it allows us to extract quantitative information from images of biological samples. Image analysis is widely used in fields such as cell biology, neuroscience, and genetics but can be applied to many other research projects. At the HAB we can help with every step of image analysis, from image preprocessing and segmentation to feature extraction, and data analysis. Machine learning or deep learning techniques may be used to automate some aspects of the analysis and to develop predictive models based on imaging data.

          metabolomics
          Metabolomics and microbiome

          The microbiome is increasingly recognized as an important contributor to host health and disease, with studies showing that disruptions to the microbiome can lead to various health problems. Metagenomics, the study of genetic material from complex microbial communities, is being increasingly used in clinical and public health research to identify pathogenic microorganisms and to study the human microbiome and its role in health and disease. At the HAB we support all the steps involved in the analysis and interpretion of large amounts of metagenomic data, including quality control, assembly, annotation, taxonomic classification, and functional analysis of metagenomic sequences.

            Activities

            bioinformatics support big
            Bioinformatics support

            At the HAB we are proud to offer a research-oriented bioinformatics core where senior bioinformaticians provide the experience and expertise a researcher could need to complement and collaborate with their own team's specific need. We are able to support scientists during different stages of a research projects, from the experimental design and grant writing to data processing, data analysis and data management. Our goal is to work together with your team to provide you with the support and guidance you need to achieve your research goals. A steering committee with a representative of each school of the Faculty of Life Science and Medicine is going to assist in the choice of which project to support in order to make sure we provide a fair service across the Faculty.

            training_big
            Training programme

            We offer a range of workshops and training programs designed to cater to different levels of expertise, from beginner to advanced. The fees for these workshops vary depending on the participant's career level and affiliation. In addition, the HAB is closely associated with an MSc programme in Applied Bioinformatics, equipping students to pursue careers in research, industry or academia.

            Internal engagement
            Internal Engagement activities

            The Hub's internal engagement activity is an important part of our mission to foster a collaborative and interdisciplinary research environment. We organize seminars, data clubs, and journal clubs around research workstreams and different applications, giving students the opportunity to share their knowledge and learn from one another. 

            Events

            10Jun

            HAB: Workshop: Git Your Code: A Bioinformatician’s Guide to Version Control

            ** This is a 2 day workshop (10 & 11 June) ** This hands-on workshop will allow you to develop familiarity with Git, a version control system that lets you...

            Please note: this event has passed.

            04Jun

            HAB: Follow-up Session: Next-Generation Sequencing (NGS) ATAC-Seq

            This workshop provides an introduction to bioinformatics workflow managers, with a focus on Nextflow. Participants will gain an understanding of workflow...

            Please note: this event has passed.

            02Jun

            Workshop: HAB: Nextflow In Action – Design and implement your own bioinformatics workflow

            This workshop provides an introduction to bioinformatics workflow managers, with a focus on Nextflow. Participants will gain an understanding of workflow...

            Please note: this event has passed.

            14May

            HAB Data Club (3rd session)

            A series of strategic lessons and a supportive meeting space for all levels to learn, share, and implement the philosophies, tools, and methodologies of...

            Please note: this event has passed.

            08May

            HAB: Workshop: An Introduction to High Performance Computing for Biologists Using CREATE

            Many research projects of biomedical interest involve the processing of extensive collections of big data files, which is often impractical on standard...

            Please note: this event has passed.

            Hot desks booking

            Be part of a community!

            The HAB is located in the room G60 of the Hodgkin building at the Guy's campus. The newly refurbished space offers an environment with 6 hot desks that can be booked through a user-friendly booking system (here), the office where the HAB staff sits, a big seminar/training room, and a kitchen area to relax and network with fellow researchers.

            If it is your first time booking a desk with us, please email us at hab@kcl.ac.uk before arriving so that we can grant you access to the HAB.

            hodgkin building

            People

            Flavia Flaviani

            Senior Bioinformatician

            Xin Yi Ng

            PhD Student

            Operations Assistant

            Michelle Simon

            Senior Bioinformatician

            Rachel  Tribe

            Vice Dean (Research & Impact)

            Themes

            genomics_and_genetics_big
            Genomics and Epigenomics

            The analysis of genomics data has revolutionized the way we approach research, opening new paths to understanding very complicated biological mechanisms, and life itself. At the HAB we offer a wide range of cutting-edge data analysis services to process, analyse, visualise and interpret genomic data. We can assist with Whole Genome and Whole Exome Sequencing data, Genome-Wide Association Studies, Comparative and Structural Comparative Genomics. We can also provide expertise in epigenomics analyses including Chromatin Accessibility Profiling, DNA Methylation Profiling and Histone Modification analysis.

              transcriptomic_and_spatial_big
              Transcriptomics and spatial transcriptomics

              At the HAB, we provide a wide variety of transcriptomic data analysis services that can be tailored to meet the needs of researchers with diverse biological questions. Our team can support analysis of bulk and single-cell RNA sequencing, Spatial Transcriptomics Assays and Single-Cell Spatial Transcriptomics as well as 3D Spatial Transcriptomics. We offer guidance in experimental design, analysis and provide expertise in selecting appropriate analysis methods, offering customized solutions to meet the specific needs of researchers.

                proteomics_big
                Proteomics

                Proteomics is a vital component of biological research, allowing us to understand the complex molecular processes that drive cellular functions. Proteomics analysis provides valuable insights into the composition, function, and interaction of proteins within a biological system. At the HAB, we support proteomics research by providing a range of analysis services, including protein identification and quantification, post-translational modification analysis, protein-protein interaction analysis, and functional analysis. Additionally, we can develop customized workflows and pipelines to suit the specific needs of research projects and provide support in analyzing and interpreting proteomics data.

                  image_analysis
                  Image analysis

                  Image analysis is an essential tool in biological research as it allows us to extract quantitative information from images of biological samples. Image analysis is widely used in fields such as cell biology, neuroscience, and genetics but can be applied to many other research projects. At the HAB we can help with every step of image analysis, from image preprocessing and segmentation to feature extraction, and data analysis. Machine learning or deep learning techniques may be used to automate some aspects of the analysis and to develop predictive models based on imaging data.

                    metabolomics
                    Metabolomics and microbiome

                    The microbiome is increasingly recognized as an important contributor to host health and disease, with studies showing that disruptions to the microbiome can lead to various health problems. Metagenomics, the study of genetic material from complex microbial communities, is being increasingly used in clinical and public health research to identify pathogenic microorganisms and to study the human microbiome and its role in health and disease. At the HAB we support all the steps involved in the analysis and interpretion of large amounts of metagenomic data, including quality control, assembly, annotation, taxonomic classification, and functional analysis of metagenomic sequences.

                      Activities

                      bioinformatics support big
                      Bioinformatics support

                      At the HAB we are proud to offer a research-oriented bioinformatics core where senior bioinformaticians provide the experience and expertise a researcher could need to complement and collaborate with their own team's specific need. We are able to support scientists during different stages of a research projects, from the experimental design and grant writing to data processing, data analysis and data management. Our goal is to work together with your team to provide you with the support and guidance you need to achieve your research goals. A steering committee with a representative of each school of the Faculty of Life Science and Medicine is going to assist in the choice of which project to support in order to make sure we provide a fair service across the Faculty.

                      training_big
                      Training programme

                      We offer a range of workshops and training programs designed to cater to different levels of expertise, from beginner to advanced. The fees for these workshops vary depending on the participant's career level and affiliation. In addition, the HAB is closely associated with an MSc programme in Applied Bioinformatics, equipping students to pursue careers in research, industry or academia.

                      Internal engagement
                      Internal Engagement activities

                      The Hub's internal engagement activity is an important part of our mission to foster a collaborative and interdisciplinary research environment. We organize seminars, data clubs, and journal clubs around research workstreams and different applications, giving students the opportunity to share their knowledge and learn from one another. 

                      Events

                      10Jun

                      HAB: Workshop: Git Your Code: A Bioinformatician’s Guide to Version Control

                      ** This is a 2 day workshop (10 & 11 June) ** This hands-on workshop will allow you to develop familiarity with Git, a version control system that lets you...

                      Please note: this event has passed.

                      04Jun

                      HAB: Follow-up Session: Next-Generation Sequencing (NGS) ATAC-Seq

                      This workshop provides an introduction to bioinformatics workflow managers, with a focus on Nextflow. Participants will gain an understanding of workflow...

                      Please note: this event has passed.

                      02Jun

                      Workshop: HAB: Nextflow In Action – Design and implement your own bioinformatics workflow

                      This workshop provides an introduction to bioinformatics workflow managers, with a focus on Nextflow. Participants will gain an understanding of workflow...

                      Please note: this event has passed.

                      14May

                      HAB Data Club (3rd session)

                      A series of strategic lessons and a supportive meeting space for all levels to learn, share, and implement the philosophies, tools, and methodologies of...

                      Please note: this event has passed.

                      08May

                      HAB: Workshop: An Introduction to High Performance Computing for Biologists Using CREATE

                      Many research projects of biomedical interest involve the processing of extensive collections of big data files, which is often impractical on standard...

                      Please note: this event has passed.

                      Hot desks booking

                      Be part of a community!

                      The HAB is located in the room G60 of the Hodgkin building at the Guy's campus. The newly refurbished space offers an environment with 6 hot desks that can be booked through a user-friendly booking system (here), the office where the HAB staff sits, a big seminar/training room, and a kitchen area to relax and network with fellow researchers.

                      If it is your first time booking a desk with us, please email us at hab@kcl.ac.uk before arriving so that we can grant you access to the HAB.

                      hodgkin building

                      logo_HAB_KCL_right

                      Group leads

                      Contact us

                      The Hub for Applied Bioinformatics is located in room G60 in the Hodgkin Building, on Guy's Campus

                      Our Social media accounts: