
Professor Rachel Tribe PhD, FPhysiol
Vice Dean (Research & Impact)
- Professor of Maternal and Perinatal Sciences
Research interests
- Women
Biography
Rachel Tribe is Professor of Maternal and Perinatal Health. She trained as a physiologist (BSc Special Dual Hons Physiology and Zoology) at the University of Sheffield and gained a PhD from the University of London focusing on dietary salt intake, sodium transport, and bronchial reactivity. Subsequently, as an American Heart Association Postdoctoral Fellow she studied smooth muscle intracellular calcium regulation at the University of Maryland at Baltimore, USA. On returning to the UK, Dr Tribe became interested in pregnancy and preterm birth and now leads a multidisciplinary research group in the Dept. of Women and Children’s Health, KCL funded by the MRC, Borne Foundation, Action Medical Research, Rosetree Trust, Leona M. and Harry B. Helmsley Charitable Trust and Tommy’s charity. Professor Tribe’s research focuses on translational research related to preterm birth and other pregnancy associated conditions. Specific interests include uterine ion channel physiology, female reproductive tract innate immune system and interactions with the microbiome in pregnancy, identification of biomarkers for prediction of preterm birth and the potential of combining breastfeeding with probiotic supplementation to improve infant gut health. Professor Tribe collaborates with colleagues in the UK, USA, Australia, Canada, Kenya, The Gambia, Mozambique and India. She has a global health portfolio of studies to understand preterm birth phenotypes and prediction in different settings, leading the PRECISE Spontaneous Preterm Birth Study and is a Co-I on the PRECISE Network.
Professor Tribe was appointed as Vice Dean for Research and Impact in the Faculty of Life Sciences & Medicine in Sept 2023 and is also the Faculty Research Integrity Champion. This role has a large focus on enhancing research capacity in the faculty, supporting research staff career development and promoting a positive research culture.
Rachel Tribe has a long standing involvement in the Physiological Society (previously on Council, Chair of the Membership & Grants Committee and Diversity/Equality Lead). Other professional roles have included membership of the Preterm Clinical Study Group Executive, Royal College of Obstetrics and Gynaecology UK and PREBIC (Preterm Birth International Collaborative) and Convenor of the Annual Myometrium and Parturition Satellite meeting for the Society of Reproductive Investigation. She is also part of the management team overseeing the collaborative UK Preterm Birth Network Clinical database; this links data from high risk pregnancies in 29 centres across the UK and abroad for research purposes.
Professor Tribe teaches biomedical and medical undergraduate students and established the interdisciplinary MSc in Women and Children’s Health. Committed to supporting early career researchers, Rachel Tribe has successfully supervised and mentored many BSc, MSc, MD and PhD students in Women’s Health.
Research

Tribe Lab
Through our mother-child cohorts, our goal is to improve outcomes for pregnant women and their children and promote health throughout the life course.
Status not set
INSIGHT-2
Mechanistic Studies into Pregnancy Complications and their Impact on Maternal and Child Health
Status not set
PISA: Prenatal drivers of infant ISlet Autoimmunity
As childhood onset of T1D becomes more prevalent, there is an increasing need to understand how early life exposures could influence the development of the child and predispose to the development of autoimmunity.
Status not set

The Hub for Applied Bioinformatics (HAB)
Welcome to the Hub for Applied Bioinformatics @KCL, a place where big data are transformed into valuable knowledge that can drive scientific breakthroughs in the fields of life sciences and medicine.
Status not set

Regulatory T Cells in Pregnancy Adverse Outcomes (Rutepo)
Tregs play a critical role in maintaining immune tolerance during pregnancy, and their dysfunction has been associated with pregnancy complications.
Project status: Ongoing
News
RNA messages can predict preterm birth
Material RNA messages from babies, mothers and placenta can predict that a baby will be born prematurely, a new study has found.

Single blood sample can detect women at risk of pre-eclampsia
A study of pregnant women’s blood RNA has found specific molecular profiles that identify women at risk of pre-eclampsia. These insights can identify...

King's research group awarded funds to investigate origins of preterm labour and birth
The group plans to map the uterus to understand the biological events driving the transition from pregnancy to established labour.

Exposure to SARS-CoV-2 during pregnancy impacts the developing immune system of the fetus
New research from King’s suggests COVID-19 infection in the mother alters the immune system of the baby in utero.

App developed to determine risk of preterm birth recommended by NHS England
A mobile-phone app and best practice toolkit used to calculate a woman’s individual risk of preterm birth were recently launched due to COVID-19 and are now...

Spotlight
Improving outcomes of high-risk pregnancy
Addressing an unmet meet need for strategies to identify women and babies at risk of serious complications of pregnancy

Research

Tribe Lab
Through our mother-child cohorts, our goal is to improve outcomes for pregnant women and their children and promote health throughout the life course.
Status not set
INSIGHT-2
Mechanistic Studies into Pregnancy Complications and their Impact on Maternal and Child Health
Status not set
PISA: Prenatal drivers of infant ISlet Autoimmunity
As childhood onset of T1D becomes more prevalent, there is an increasing need to understand how early life exposures could influence the development of the child and predispose to the development of autoimmunity.
Status not set

The Hub for Applied Bioinformatics (HAB)
Welcome to the Hub for Applied Bioinformatics @KCL, a place where big data are transformed into valuable knowledge that can drive scientific breakthroughs in the fields of life sciences and medicine.
Status not set

Regulatory T Cells in Pregnancy Adverse Outcomes (Rutepo)
Tregs play a critical role in maintaining immune tolerance during pregnancy, and their dysfunction has been associated with pregnancy complications.
Project status: Ongoing
News
RNA messages can predict preterm birth
Material RNA messages from babies, mothers and placenta can predict that a baby will be born prematurely, a new study has found.

Single blood sample can detect women at risk of pre-eclampsia
A study of pregnant women’s blood RNA has found specific molecular profiles that identify women at risk of pre-eclampsia. These insights can identify...

King's research group awarded funds to investigate origins of preterm labour and birth
The group plans to map the uterus to understand the biological events driving the transition from pregnancy to established labour.

Exposure to SARS-CoV-2 during pregnancy impacts the developing immune system of the fetus
New research from King’s suggests COVID-19 infection in the mother alters the immune system of the baby in utero.

App developed to determine risk of preterm birth recommended by NHS England
A mobile-phone app and best practice toolkit used to calculate a woman’s individual risk of preterm birth were recently launched due to COVID-19 and are now...

Spotlight
Improving outcomes of high-risk pregnancy
Addressing an unmet meet need for strategies to identify women and babies at risk of serious complications of pregnancy
