Bioinformatics (Research) MPhil/PhD
MPhil/PhD Bioinformatics Research at King's College London
Senior Lecturer
Alessandra Vigilante (AV) is a Senior Lecturer in Bioinformatics at the Center for Stem Cells and Regenerative Medicine with a focus on genotype- phenotype interactions and data integration. AV obtained her PhD in Bioinformatics in Naples (2008-2011) before moving the UK to join Nicholas Luscombe group first at the EMBL-European Bioinformatics Institute as a visiting student (2011-2012) and then as a postdoctoral fellow at UCL (2012-2017). Alessandra Vigilante’s group has significant expertise and experience in the analysis and integration of large scale genomic, epigenomic and transcriptomic data (i.e. single-cell RNA-seq and ATAC-seq datasets, ChIP-seq etc…), and in the implementation of novel computational methods for various bespoke analyses to gain biological insights. AV is actively involved in a great network of collaborations to develop multidisciplinary approaches to research efforts, working with faculty members within King’s and other research institutes.
Our primary research areas can be broadly classified as: Use of integration approaches to uncover genotype–phenotype interactions; and,Use of single-cell RNA sequencing to study developmental and stem cell biology
Understanding organ development and tissue regeneration provides a framework for elucidating disease mechanisms as well as for developing new therapeutics.
Welcome to the Hub for Applied Bioinformatics @KCL, a place where big data are transformed into valuable knowledge that can drive scientific breakthroughs in the fields of life sciences and medicine.
Our primary research areas can be broadly classified as: Use of integration approaches to uncover genotype–phenotype interactions; and,Use of single-cell RNA sequencing to study developmental and stem cell biology
Understanding organ development and tissue regeneration provides a framework for elucidating disease mechanisms as well as for developing new therapeutics.
Welcome to the Hub for Applied Bioinformatics @KCL, a place where big data are transformed into valuable knowledge that can drive scientific breakthroughs in the fields of life sciences and medicine.