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Recent publications


Publications 2016

1.         Abbate, V.; Reelfs, O.; Kong, X.; Pourzand, C.; Hider, R. C., Dual selective iron chelating probes with a potential to monitor mitochondrial labile iron pools. Chemical Communications 2016, 52, (4), 784-787.

2.         Barton, L. L.; Lyle, D. A.; Ritz, N. L.; Granat, A. S.; Khurshid, A. N.; Kherbik, N.; Hider, R.; Lin, H. C., Bismuth(III) deferiprone effectively inhibits growth of Desulfovibrio desulfuricans ATCC 27774. Biometals 2016, 29, (2), 311-319.

3.         Bayele, H. K.; Debnam, E. S.; Srai, K. S., Nrf2 transcriptional derepression from Keap1 by dietary polyphenols. Biochemical and Biophysical Research Communications 2016, 469, (3), 521-528.

4.         Cappellini, M. D.; Porter, J. B.; Musallam, K. M.; Kattamis, A.; Viprakasit, V.; Galanello, R.; Taher, A. T., Development of a new disease severity scoring system for patients with non-transfusion-dependent thalassemia. European Journal of Internal Medicine 2016, 28, 91-96.

5.         Cathriona, R. L.; Sandra, D. O.; Dell; Paul, A. S.; Anne, M., Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes. Current HIV research 2016, 14, (1), 37-46.

6.         Crespo, G.; Castro-Narro, G.; Garcia-Juarez, I.; Benitez, C.; Ruiz, P.; Sastre, L.; Colmenero, J.; Miquel, R.; Sanchez-Fueyo, A.; Forns, X.; Navasa, M., Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation. Liver Transplantation 2016, 22, (3), 298-304.

7.         Dumontet, E.; Danger, R.; Vagefi, P. A.; Londono, M.-C.; Pallier, A.; Jose Lozano, J.; Giral, M.; Degauque, N.; Soulillou, J.-P.; Martinez-Llordella, M.; Lee, H.; Latournerie, M.; Boudjema, K.; Dulong, J.; Tarte, K.; Sanchez-Fueyo, A.; Feng, S.; Brouard, S.; Conchon, S., Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients. Liver International 2016, 36, (3), 401-409.

8.         Gooch, J.; Abbate, V.; Daniel, B.; Frascione, N., Solid-phase synthesis of Rhodamine-110 fluorogenic substrates and their application in forensic analysis. Analyst 2016, 141, (8), 2392-2395.

9.         Gooch, J.; Goh, H.; Daniel, B.; Abbate, V.; Frascione, N., Monitoring Criminal Activity through Invisible Fluorescent “Peptide Coding” Taggants. Analytical Chemistry 2016, 88, (8), 4456-4460.

10.       Gunderwala, A.; Porter, J., A luminescence assay for natural product inhibitors of the Mycobacterium tuberculosis proteasome. Phytochemical Analysis 2016, 27, (2), 126-132.

11.       Harrison, I. F.; Anis, H. K.; Dexter, D. T., Associated degeneration of ventral tegmental area dopaminergic neurons in the rat nigrostriatal lactacystin model of parkinsonism and their neuroprotection by valproate. Neuroscience Letters 2016, 614, 16-23.

12.       Hassan, H. A. F. M.; Smyth, L.; Rubio, N.; Ratnasothy, K.; Wang, J. T. W.; Bansal, S. S.; Summers, H. D.; Diebold, S. S.; Lombardi, G.; Al-Jamal, K. T., Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo. Journal of Controlled Release 2016, 225, 205-216.

13.       Hogstrand, C.; Maret, W., Genetics of Human Zinc Deficiencies. In eLS, John Wiley & Sons, Ltd: 2016.

14.       Kafa, H.; Wang, J. T.-W.; Rubio, N.; Klippstein, R.; Costa, P. M.; Hassan, H. A. F. M.; Sosabowski, J. K.; Bansal, S. S.; Preston, J. E.; Abbott, N. J.; Al-Jamal, K. T., Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo. Journal of Controlled Release 2016, 225, 217-229.

15.       Kasana, S.; Din, J.; Maret, W., Genetic causes and gene–nutrient interactions in mammalian zinc deficiencies: Acrodermatitis enteropathica and transient neonatal zinc deficiency as examples. Journal of Trace Elements in Medicine and Biology 2015, 29, 47-62.

16.       Koo, K. A.; Waisbourd-Zinman, O.; Wells, R. G.; Pack, M.; Porter, J. R., Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids. Chemical Research in Toxicology 2016, 29, (2), 142-149.

17.       Kulprachakarn, K.; Chen, Y.-L.; Kong, X.; Arno, M. C.; Hider, R. C.; Srichairatanakool, S.; Bansal, S. S., Copper(II) binding properties of hepcidin. JBIC Journal of Biological Inorganic Chemistry 2016, 1-10.

18.       Latunde_Dada, G. O., Biosynthesis and significance of Heme. In The Encyclopedia of Food and Health, Caballero, B.; Finglas, P.; TOldra', F., Eds. Oxford: Academic Press: 2016; Vol. 3, pp 452-460.

19.       Latunde-Dada, G. O., Is the calcium transporter a potential candidate for heme transport? Medical Hypotheses 2016, 91, 84-85.

20.       Lesage, S.; Drouet, V.; Majounie, E.; Deramecourt, V.; Jacoupy, M.; Nicolas, A.; Cormier-Dequaire, F.; Hassoun, S. M.; Pujol, C.; Ciura, S.; Erpapazoglou, Z.; Usenko, T.; Maurage, C.-A.; Sahbatou, M.; Liebau, S.; Ding, J.; Bilgic, B.; Emre, M.; Erginel-Unaltuna, N.; Guven, G.; Tison, F.; Tranchant, C.; Vidailhet, M.; Corvol, J.-C.; Krack, P.; Leutenegger, A.-L.; Nalls, M. A.; Hernandez, D. G.; Heutink, P.; Gibbs, J. R.; Hardy, J.; Wood, N. W.; Gasser, T.; Durr, A.; Deleuze, J.-F.; Tazir, M.; Destee, A.; Lohmann, E.; Kabashi, E.; Singleton, A.; Corti, O.; Brice, A.; French Parkinson's Dis Genetics, S.; Ipdgc, Loss of VPS1 3C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy. American Journal of Human Genetics 2016, 98, (3), 500-513.

21.       Li, J.; Abbate, V.; Jurach, J.; Zhang, G.; Kong, X.; Hider, R. C., 5-Hydroxypyran-4-one derivatives as potential therapeutic iron–chelating agents. ChemistrySelect 2016, 1, (2), 297-300.

22.       Li, J.; Olaleye, E. D.; Kong, X.; Zhou, T.; Ma, Y.; Jurach, J.; Al Rugaie, O.; Hider, R. C.; Zhang, G.; Alsam, S.; Abbate, V., Macromolecular iron-chelators via RAFT-polymerization for the inhibition of methicillin-resistant Staphylococcus aureus growth. Polymer 2016, 87, 64-72.

23.       Loonam, C. R.; O'Dell, S. D.; Sharp, P. A.; Mullen, A., Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes. Current HIV research 2016, 14, (1), 37-46.

24.       Loonat, S. B.; Naran, N. H.; Thein, S. L.; Alli, N. A., Alpha-thalassaemia trait as a cause of unexplained microcytosis in a South African population. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2016, 106, (3), 276-9.

25.       Lunt, A.; Ahmed, N.; Rafferty, G. F.; Dick, M.; Rees, D.; Height, S.; Thein, S. L.; Greenough, A., Airway and alveolar nitric oxide production, lung function, and pulmonary blood flow in sickle cell disease. Pediatric Research 2016, 79, (2), 313-317.

26.       Maret, W., The Metals in the Biological Periodic System of the Elements: Concepts and Conjectures. International journal of molecular sciences 2016, 17, (1).

27.       Maret, W.; Adams, M.; Austin, R.; Chen, C.; Giedroc, D.; Bayon, M. M.; Ogra, Y.; Orvig, C.; Zamble, D.; Keltie, S.; Ross, P., The scope of Metallomics. Metallomics 2016, 8, (1), 8-8.

28.       Mason, K.; Gibson, F.; Higgs, D.; Fisher, C.; Thein, S. L.; Clark, B.; Kulozik, A.; Happich, M.; Serjeant, B.; Serjeant, G., Haemoglobin Variant Screening in Jamaica: Meeting Student's Request. British Journal of Haematology 2016, 172, (4), 634-636.

29.       Mastoridis, S.; Martinez-Llordella, M.; Sanchez-Fueyo, A., Biomarkers and immunopathology of tolerance. Current Opinion in Organ Transplantation 2016, 21, (1), 81-87.

30.       Oliveira, A.; Warcel, D.; Huntley, N.; Eleftheriou, P.; Porter, J. B., Symptomatic Erythrocytosis Due to Homozygosity for Hb Luton HBA2: c.269A > T (or HBA1) and alpha-Thalassemia: A Clinical Update. Hemoglobin 2016, 40, (2), 127-129.

31.       Olowu, W. A.; Niang, A.; Osafo, C.; Ashuntantang, G.; Arogundade, F. A.; Porter, J.; Naicker, S.; Luyckx, V. A., Outcomes of acute kidney injury in children and adults in sub-Saharan Africa: a systematic review. The Lancet. Global health 2016, 4, (4), e242-50.

32.       Pechlaner, R.; Kiechl, S.; Mayr, M.; Santer, P.; Weger, S.; Haschka, D.; Bansal, S. S.; Willeit, J.; Weiss, G., Correlates of serum hepcidin levels and its association with cardiovascular disease in an elderly general population. Clinical Chemistry and Laboratory Medicine 2016, 54, (1), 151-161.

33.       Pechlaner, R.; Weiss, G.; Bansal, S.; Mayr, M.; Santer, P.; Pallhuber, B.; Notdurfter, M.; Bonora, E.; Willeit, J.; Kiechl, S., Inadequate hepcidin serum concentrations predict incident type 2 diabetes mellitus. Diabetes-Metabolism Research and Reviews 2016, 32, (2), 187-192.

34.       Porter, J. B.; de Witte, T.; Cappellini, M. D.; Gattermann, N., New insights into transfusion-related iron toxicity: Implications for the oncologist. Critical Reviews in Oncology Hematology 2016, 99, 261-271.

35.       Porter, J. B.; El-Alfy, M.; Viprakasit, V.; Giraudier, S.; Chan, L. L.; Lai, Y. R.; Ali El, A.; Han, J.; Cappellini, M. D., Utility of labile plasma iron and transferrin saturation in addition to serum ferritin as iron overload markers in different underlying anemias before and after deferasirox treatment. European Journal of Haematology 2016, 96, (1), 19-26.

36.       Porter, J. R.; Durand, J.-L.; Elmayan, T., Edited plants should not be patented. Nature 2016, 530, (7588), 33-33.

37.       Rutter, G. A.; Chabosseau, P.; Bellomo, E. A.; Maret, W.; Mitchell, R. K.; Hodson, D. J.; Solomou, A.; Hu, M., Intracellular zinc in insulin secretion and action: a determinant of diabetes risk? Proceedings of the Nutrition Society 2016, 7, (1), 61-72.

38.       Safinia, N.; Vaikunthanathan, T.; Fraser, H.; Thirkell, S.; Lowe, K.; Blackmore, L.; Whitehouse, G.; Martinez-Llordella, M.; Jassem, W.; Sanchez-Fueyo, A.; Lechler, R. I.; Lombardi, G., Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation. Oncotarget 2016, 7, (7), 7563-7577.

39.       Santos, C. X. C.; Hafstad, A. D.; Beretta, M.; Zhang, M.; Molenaar, C.; Kopec, J.; Fotinou, D.; Murray, T. V.; Cobb, A. M.; Martin, D.; Silva, M. Z.; Anilkumar, N.; Schroder, K.; Shanahan, C. M.; Brewer, A. C.; Brandes, R. P.; Blanc, E.; Parsons, M.; Belousov, V.; Cammack, R.; Hider, R. C.; Steiner, R. A.; Shah, A. M., Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2 alpha-mediated stress signaling. Embo Journal 2016, 35, (3), 319-334.

40.       Schnell, S.; Stott, L. C.; Hogstrand, C.; Wood, C. M.; Kelly, S. P.; Part, P.; Owen, S. F.; Bury, N. R., Procedures for the reconstruction, primary culture and experimental use of rainbow trout gill epithelia. Nature Protocols 2016, 11, (3), 490-498.

41.       Song, Y. F.; Luo, Z.; Zhang, L. H.; Hogstrand, C.; Pan, Y. X., Endoplasmic reticulum stress and disturbed calcium homeostasis are involved in copper-induced alteration in hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Chemosphere 2016, 144, 2443-2453.

42.       Taher, A. T.; Cappellini, M. D.; Aydinok, Y.; Porter, J. B.; Karakas, Z.; Viprakasit, V.; Siritanaratkul, N.; Kattamis, A.; Wang, C.; Zhu, Z.; Joaquin, V.; Uwamahoro, M. J.; Lai, Y.-R., Optimising iron chelation therapy with deferasirox for non-transfusion-dependent thalassaemia patients: 1-year results from the THETIS study. Blood Cells Molecules and Diseases 2016, 57, 23-29.

43.       Xie, Y.-Y.; Lu, Z.; Kong, X.-L.; Zhou, T.; Bansal, S.; Hider, R., Systematic comparison of the mono-, dimethyl- and trimethyl 3-hydroxy-4(1H)-pyridones – Attempted optimization of the orally active iron chelator, deferiprone. European Journal of Medicinal Chemistry 2016, 115, 132-140.


Publications 2015

1.         Abbate, V.; Kicman, A. T.; Evans-Brown, M.; McVeigh, J.; Cowan, D. A.; Wilson, C.; Coles, S. J.; Walker, C. J., Anabolic steroids detected in bodybuilding dietary supplements – a significant risk to public health. Drug Testing and Analysis 2015, 7, (7), 609-618.

2.         Abbate, V.; Reelfs, O.; Hider, R. C.; Pourzand, C., Design of novel fluorescent mitochondria-targeted peptides with iron-selective sensing activity. Biochem. J. 2015, 469, 357-366.

3.         Abbate, V.; Reelfs, O.; Kong, X.; Pourzand, C.; Hider, R. C., Dual selective iron chelating probes with a potential to monitor mitochondrial labile iron pools. Chemical communications (Cambridge, England) 2015, 52, (4), 784-7.

4.         Adams, D. H.; Sanchez-Fueyo, A.; Samuel, D., From immunosuppression to tolerance. Journal of Hepatology 2015, 62, S170-S185.

5.         Adekile, A.; Menzel, S.; Gupta, R.; Al-Sharida, S.; Azab, A. F.; Haider, M.; Akbulut, N.; Mustafa, N.; Thein, S. L., Response to hydroxyurea among Kuwaiti patients with sickle cell disease and elevated baseline HbF levels. American Journal of Hematology 2015, 90, (7), E138-E139.

6.         Ahmad Khanbeigi, R.; Abelha, T. F.; Woods, A.; Rastoin, O.; Harvey, R. D.; Jones, M.-C.; Forbes, B.; Green, M. A.; Collins, H.; Dailey, L. A., Surface Chemistry of Photoluminescent F8BT Conjugated Polymer Nanoparticles Determines Protein Corona Formation and Internalization by Phagocytic Cells. Biomacromolecules 2015, 16, (3), 733-742.

7.         Aydinok, Y.; Kattamis, A.; Cappellini, M. D.; El-Beshlawy, A.; Origa, R.; Elalfy, M.; Kilinc, Y.; Perrotta, S.; Karakas, Z.; Viprakasit, V.; Habr, D.; Constantinovici, N.; Shen, J. W.; Porter, J. B.; Investigators, H., Effects of deferasirox-deferoxamine on myocardial and liver iron in patients with severe transfusional iron overload. Blood 2015, 125, (25), 3868-3877.

8.         Aydinok, Y.; Porter, J. B.; Piga, A.; Elalfy, M.; El-Beshlawy, A.; Kilinc, Y.; Viprakasit, V.; Yesilipek, A.; Habr, D.; Quebe-Fehling, E.; Pennell, D. J., Prevalence and distribution of iron overload in patients with transfusion-dependent anemias differs across geographic regions: results from the CORDELIA study. European Journal of Haematology 2015, 95, (3), 244-253.

9.         Baker, P. W.; Högstrand, C.; Lead, J.; Pickup, R. W.; Zhang, H., Immobilization of Shewanella oneidensis MR-1 in diffusive gradients in thin films for determining metal bioavailability. Chemosphere 2015, 138, 309-315.

10.       Baron, D.; Ramstein, G.; Chesneau, M.; Echasseriau, Y.; Pallier, A.; Paul, C.; Degauque, N.; Hernandez-Fuentes, M. P.; Sanchez-Fueyo, A.; Newell, K. A.; Giral, M.; Soulillou, J. P.; Houlgatte, R.; Brouard, S., A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft. Kidney International 2015, 87, (5), 984-995.

11.       Bonaccorsi-Riani, E.; Danger, R.; Lozano, J. J.; Martinez-Picola, M.; Kodela, E.; Mas-Malavila, R.; Bruguera, M.; Collins, H. L.; Hider, R. C.; Martinez-Llordella, M.; Sanchez-Fueyo, A., Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response. Plos One 2015, 10, (8).

12.       Brauer, R.; Bhaskaran, K.; Chaturvedi, N.; Dexter, D. T.; Smeeth, L.; Douglas, I., Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study. Plos Medicine 2015, 12, (7).

13.       Chen, Y. L.; Chen, J.; Ma, Y. M.; Hider, R. C., The Synthesis of 5-Functional 3-Hydroxypyridin-4-ones and Their Impact on the Chelating Properties of the Ligands. Chemistry Letters 2015, 44, (4), 515-517.

14.       Christides, T.; Wray, D.; McBride, R.; Fairweather, R.; Sharp, P., Iron bioavailability from commercially available iron supplements. European Journal of Nutrition 2015, 54, (8), 1345-1352.

15.       Danjou, F.; Zoledziewska, M.; Sidore, C.; Steri, M.; Busonero, F.; Maschio, A.; Mulas, A.; Perseu, L.; Barella, S.; Porcu, E.; Pistis, G.; Pitzalis, M.; Pala, M.; Menzel, S.; Metrustry, S.; Spector, T. D.; Leoni, L.; Angius, A.; Uda, M.; Moi, P.; Thein, S. L.; Galanello, R.; Abecasis, G. R.; Schlessinger, D.; Sanna, S.; Cucca, F., Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels. Nature Genetics 2015, 47, (11), 1264-+.

16.       Di Fruscia, P.; Zacharioudakis, E.; Liu, C.; Moniot, S.; Laohasinnarong, S.; Khongkow, M.; Harrison, I. F.; Koltsida, K.; Reynolds, C. R.; Schmidtkunz, K.; Jung, M.; Chapman, K. L.; Steegborn, C.; Dexter, D. T.; Sternberg, M. J. E.; Lam, E. W. F.; Fuchter, M. J., The Discovery of a Highly Selective 5,6,7,8-Tetrahydrobenzo[4,5]thieno[ 2,3-d] pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson's Disease Model. Chemmedchem 2015, 10, (1), 69-82.

17.       Diaz-Castro, J.; Moreno-Fernandez, J.; Hijano, S.; Kajarabille, N.; Pulido-Moran, M.; Latunde-Dada, G. O.; Hurtado, J. A.; Pena, M.; Pena-Quintana, L.; Lara-Villoslada, F.; Ochoa, J. J., DHA supplementation: A nutritional strategy to improve prenatal Fe homeostasis and prevent birth outcomes related with Fe-deficiency. Journal of Functional Foods 2015, 19, 385-393.

18.       Durrenberger, P. F.; Fernando, F. S.; Kashefi, S. N.; Bonnert, T. P.; Seilhean, D.; Nait-Oumesmar, B.; Schmitt, A.; Gebicke-Haerter, P. J.; Falkai, P.; Grunblatt, E.; Palkovits, M.; Arzberger, T.; Kretzschmar, H.; Dexter, D. T.; Reynolds, R., Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study. Journal of Neural Transmission 2015, 122, (7), 1055-1068.

19.       Frascione, N.; Gooch, J.; Abbate, V.; Daniel, B., Fluorogenic displacement biosensors for PSA detection using antibody-functionalised quantum dot nanoparticles. RSC Advances 2015, 5, (9), 6595-6598.

20.       Gambari, R.; Kleanthous, M.; Philipsen, S.; Katsantoni, E.; Rivella, S.; Holub, P.; Moi, P.; Thein, S. L.; Voskaridou, E.; Afantitis, A.; Fibach, E.; Klein, O.; Drabek, D.; Bresciani, A.; Consortium, T., Thalassemia Modular Stratification System for Personalized Therapy of Beta-Thalassemia (THALAMOSS). Human Gene Therapy Clinical Development 2015, 26, (2), 100-102.

21.       Gardner, K.; Thein, S. L., Super-elevated LDH and thrombocytopenia are markers of a severe subtype of vaso-occlusive crisis in sickle cell disease. American Journal of Hematology 2015, 90, (10), E206-7.

22.       Gooch, J.; Koh, C.; Daniel, B.; Abbate, V.; Frascione, N., Establishing evidence of contact transfer in criminal investigation by a novel ‘peptide coding’ reagent. Talanta 2015, 144, 1065-1069.

23.       Goode, A. E.; Carter, D. A. G.; Motskin, M.; Pienaar, I. S.; Chen, S.; Hu, S.; Ruenraroengsak, P.; Ryan, M. P.; Shaffer, M. S. P.; Dexter, D. T.; Porter, A. E., High resolution and dynamic imaging of biopersistence and bioreactivity of extra and intracellular MWNTs exposed to microglial cells. Biomaterials 2015, 70, 57-70.

24.       Harrison, I. F.; Crum, W. R.; Vernon, A. C.; Dexter, D. T., Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors. British Journal of Pharmacology 2015, 172, (16), 4200-4215.

25.       Hider, R. C.; Kong, X.; Abbate, V.; Harland, R.; Conlon, K.; Luker, T., Deferitazole, a new orally active iron chelator. Dalton Transactions 2015, 44, (11), 5197-5204.

26.       Hider, R. C.; Maret, W., Iron and zinc sensing in cells and the body. Metallomics 2015, 7, (2), 200-201.

27.       Hoffman, E.; Kumar, A.; Kanabar, V.; Arno, M.; Preux, L.; Millar, V.; Page, C.; Collins, H.; Mudway, I.; Dailey, L. A.; Forbes, B., In Vitro Multiparameter Assay Development Strategy toward Differentiating Macrophage Responses to Inhaled Medicines. Molecular Pharmaceutics 2015, 12, (8), 2675-2687.

28.       Horniblow, R. D.; Dowle, M.; Iqbal, T. H.; Latunde-Dada, G. O.; Palmer, R. E.; Pikramenou, Z.; Tselepis, C., Alginate-Iron Speciation and Its Effect on In Vitro Cellular Iron Metabolism. Plos One 2015, 10, (9), e0138240.

29.       Howard, J.; Inusa, B.; Liossi, C.; Jacob, E.; Murphy, P. B.; Hart, N.; Gavlak, J.; Sahota, S.; Chorozoglou, M.; Nwosu, C.; Gwam, M.; Gupta, A.; Rees, D. C.; Thein, S. L.; Reading, I. C.; Kirkham, F. J.; Cheng, M. Y. E., Prevention of Morbidity in sickle cell disease - qualitative outcomes, pain and quality of life in a randomised cross-over pilot trial of overnight supplementary oxygen and auto-adjusting continuous positive airways pressure (POMS2a): study protocol for a randomised controlled trial. Trials 2015, 16.

30.       Hurley, M. J.; Durrenberger, P. F.; Gentleman, S. M.; Walls, A. F.; Dexter, D. T., Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease. Journal of Molecular Neuroscience 2015, 57, (1), 48-62.

31.       Hurley, M. J.; Gentleman, S. M.; Dexter, D. T., Calcium Ca(V)1 Channel Subtype mRNA Expression in Parkinson's Disease Examined by In Situ Hybridization. Journal of Molecular Neuroscience 2015, 55, (3), 715-724.

32.       Jones, E.; Pasricha, S. R.; Allen, A.; Evans, P.; Fisher, C. A.; Wray, K.; Premawardhena, A.; Bandara, D.; Perera, A.; Webster, C.; Sturges, P.; Olivieri, N. F.; St Pierre, T.; Armitage, A. E.; Porter, J. B.; Weatherall, D. J.; Drakesmith, H., Hepcidin is suppressed by erythropoiesis in hemoglobin E beta-thalassemia and beta-thalassemia trait. Blood 2015, 125, (5), 873-880.

33.       Kasana, S.; Din, J.; Maret, W., Genetic causes and gene-nutrient interactions in mammalian zinc deficiencies: Acrodermatitis enteropathica and transient neonatal zinc deficiency as examples. Journal of Trace Elements in Medicine and Biology 2015, 29, 47-62.

34.       Khanbeigi, R. A.; Hashim, Z.; Abelha, T. F.; Pitchford, S.; Collins, H.; Green, M.; Dailey, L. A., Interactions of stealth conjugated polymer nanoparticles with human whole blood. Journal of Materials Chemistry B 2015, 3, (12), 2463-2471.

35.       Klioueva, N. M.; Rademaker, M. C.; Dexter, D. T.; Al-Sarraj, S.; Seilhean, D.; Streichenberger, N.; Schmitz, P.; Bell, J. E.; Ironside, J. W.; Arzberger, T.; Huitinga, I., BrainNet Europe's Code of Conduct for brain banking. Journal of Neural Transmission 2015, 122, (7), 937-940.

36.       Klippstein, R.; Wang, J. T.-W.; El-Gogary, R. I.; Bai, J.; Mustafa, F.; Rubio, N.; Bansal, S.; Al-Jamal, W. T.; Al-Jamal, K. T., Passively Targeted Curcumin-Loaded PEGylated PLGA Nanocapsules for Colon Cancer Therapy In Vivo. Small (Weinheim an der Bergstrasse, Germany) 2015, 11, (36), 4704-22.

37.       Koumoutsea, E. V.; Garbowski, M.; Porter, J., Synergistic intracellular iron chelation combinations: mechanisms and conditions for optimizing iron mobilization. British Journal of Haematology 2015, 170, (6), 874-883.

38.       Li, J. P.; Lu, Z. D.; Kong, X. L.; Ma, Y. M.; Zhang, X. Y.; Bansal, S. S.; Abbate, V.; Hider, R. C., Design and synthesis of novel pegylated iron chelators with decreased metabolic rate. Future Medicinal Chemistry 2015, 7, (18), 2439-2449.

39.       Lynch, S. K.; Ahanchi, S. S.; Dexter, D. J.; Glickman, M. H.; Panneton, J. M., Patient compliance limits the efforts of quality improvement initiatives on arteriovenous fistula maturation. Journal of Vascular Surgery 2015, 61, (1), 184-191.

40.       Ma, M. T.; Meszaros, L. K.; Paterson, B. M.; Berry, D. J.; Cooper, M. S.; Ma, Y.; Hider, R. C.; Blower, P. J., Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: comparison with desferrioxamine-B. Dalton Transactions 2015, 44, (11), 4884-4900.

41.       Ma, Y.; Abbate, V.; Hider, R. C., Iron-sensitive fluorescent probes: monitoring intracellular iron pools. Metallomics 2015, 7, (2), 212-222.

42.       Ma, Y.; Hider, R. C., Novel synthetic approach to fluoro- and amido-disubstituted 3-hydroxypyridin-4-ones. Journal of Fluorine Chemistry 2015, 173, (0), 29-34.

43.       Ma, Y.; Kong, X.; Abbate, V.; Hider, R. C., Synthesis and characterization of novel iron-specific bicyclic fluorescent probes. Sensors and Actuators B: Chemical 2015, 213, 12-19.

44.       Ma, Y.; Zhou, T.; Hider, R. C., pFe3+ determination of multidentate ligands by a fluorescence assay. Analyst 2015, 140, (10), 3603-3606.

45.       Maret, W., Analyzing free zinc(ii) ion concentrations in cell biology with fluorescent chelating molecules. Metallomics 2015, 7, (2), 202-211.

46.       Maret, W.; Caruso, J. A.; Contag, C. H.; Giedroc, D. P.; Hagedoorn, P.; Matusch, A.; Skaar, E. P.; Thompson, R. B., Methods and Technologies for Studying Metals in Biological Systems. In Trace Metals and Infectious Diseases, Nriagu, O. J.; Skaar, E. P., Eds. MIT Press: Cambridge (MA), 2015.

47.       Mastoridis, S.; Martinez-Llordella, M.; Sanchez-Fueyo, A., Emergent transcriptomic technologies and their role in the discovery of biomarkers of liver transplant tolerance. Frontiers in Immunology 2015, 6.

48.       Mathew, R.; Bafiq, R.; Ramu, J.; Pearce, E.; Richardson, M.; Drasar, E.; Thein, S. L.; Sivaprasad, S., Spectral domain optical coherence tomography in patients with sickle cell disease. British Journal of Ophthalmology 2015, 99, (7), 967-972.

49.       Mei, K. C.; Guo, Y.; Bai, J.; Costa, P. M.; Kafa, H.; Protti, A.; Hider, R. C.; Al-Jamal, K. T., Organic Solvent-Free, One-Step Engineering of Graphene-Based Magnetic-Responsive Hybrids Using Design of Experiment-Driven Mechanochemistry. ACS Applied Materials & Interfaces 2015, 7, (26), 14176-14181.

50.       Mei, K.-C.; Rubio, N.; Costa, P. M.; Kafa, H.; Abbate, V.; Festy, F.; Bansal, S. S.; Hider, R. C.; Al-Jamal, K. T., Synthesis of double-clickable functionalised graphene oxide for biological applications. Chemical Communications 2015, 51, (81), 14981-14984.

51.       Morris, C. R.; Kim, H. Y.; Klings, E. S.; Wood, J.; Porter, J. B.; Trachtenberg, F.; Sweeters, N.; Olivieri, N. F.; Kwiatkowski, J. L.; Virzi, L.; Hassell, K.; Taher, A.; Neufeld, E. J.; Thompson, A. A.; Larkin, S.; Suh, J. H.; Vichinsky, E. P.; Kuypers, F. A.; Thalassemia Clinical Res, N., Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia. British Journal of Haematology 2015, 169, (6), 887-898.

52.       Mtatiro, S. N.; Makani, J.; Mmbando, B.; Thein, S. L.; Menzel, S.; Cox, S. E., Genetic variants at HbF-modifier loci moderate anemia and leukocytosis in sickle cell disease in Tanzania. American Journal of Hematology 2015, 90, (1), E1-E4.

53.       Mtatiro, S. N.; Mgaya, J.; Singh, T.; Mariki, H.; Rooks, H.; Soka, D.; Mmbando, B.; Thein, S. L.; Barrett, J. C.; Makani, J.; Cox, S. E.; Menzel, S., Genetic association of fetal-hemoglobin levels in individuals with sickle cell disease in Tanzania maps to conserved regulatory elements within the MYB core enhancer. Bmc Medical Genetics 2015, 16.

54.       Mushemi-Blake, S.; Melikian, N.; Drasar, E.; Bhan, A.; Lunt, A.; Desai, S. R.; Greenough, A.; Monaghan, M. J.; Thein, S. L.; Shah, A. M., Pulmonary Haemodynamics in Sickle Cell Disease Are Driven Predominantly by a High-Output State Rather Than Elevated Pulmonary Vascular Resistance: A Prospective 3-Dimensional Echocardiography/Doppler Study. Plos One 2015, 10, (8).

55.       Nalls, M. A.; Bras, J.; Hernandez, D. G.; Keller, M. F.; Majounie, E.; Renton, A. E.; Saad, M.; Jansen, I.; Guerreiro, R.; Lubbe, S.; Plagnol, V.; Gibbs, J. R.; Schulte, C.; Pankratz, N.; Sutherland, M.; Bertram, L.; Lill, C. M.; DeStefano, A. L.; Faroud, T.; Eriksson, N.; Tung, J. Y.; Edsall, C.; Nichols, N.; Brooks, J.; Arepalli, S.; Pliner, H.; Letson, C.; Heutink, P.; Martinez, M.; Gasser, T.; Traynor, B. J.; Wood, N.; Hardy, J.; Singleton, A. B.; Int Parkinson's Dis Genomics, C.; Parkinson's Dis Meta-Anal, C., NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases. Neurobiology of Aging 2015, 36, (3).

56.       Pangjit, K.; Banjerdpongchai, R.; Phisalaphong, C.; Fucharoen, S.; Xie, Y. Y.; Lu, Z. D.; Hider, R. C.; Srichairatanakool, S., Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one. Journal of Pharmacy and Pharmacology 2015, 67, (5), 703-713.

57.       Pennell, D. J.; Porter, J. B.; Piga, A.; Lai, Y. R.; El-Beshlawy, A.; Elalfy, M.; Yesilipek, A.; Kilinc, Y.; Habr, D.; Musallam, K. M.; Shen, J. W.; Aydinok, Y.; Investigators, C. S., Sustained improvements in myocardial T2*over 2 years in severely iron-overloaded patients with beta thalassemia major treated with deferasirox or deferoxamine. American Journal of Hematology 2015, 90, (2), 91-96.

58.       Pienaar, I. S.; Gartside, S. E.; Sharma, P.; De Paola, V.; Gretenkord, S.; Withers, D.; Elson, J. L.; Dexter, D. T., Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease. Molecular Neurodegeneration 2015, 10.

59.       Pienaar, I. S.; Harrison, I. F.; Elson, J. L.; Bury, A.; Woll, P.; Simon, A. K.; Dexter, D. T., An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease. Brain Struct Funct 2015, 220, (1), 479-500.

60.       Pienaar, I. S.; Lee, C. H.; Elson, J. L.; McGuinness, L.; Gentleman, S. M.; Kalaria, R. N.; Dexter, D. T., Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease. Neurobiology of Disease 2015, 74, 392-405.

61.       Rees, D. C.; Thein, S. L.; Osei, A.; Drasar, E.; Tewari, S.; Hannemann, A.; Gibson, J. S., The clinical significance of K-Cl cotransport activity in red cells of patients with HbSC disease. Haematologica 2015, 100, (5), 595-600.

62.       Rubio, N.; Hirvonen, L. M.; Chong, E. Z.; Wang, J. T. W.; Bourgognon, M.; Kafa, H.; Hassan, H.; Al-Jamal, W. T.; McCarthy, D.; Hogstrand, C.; Festy, F.; Al-Jamal, K. T., Multiphoton luminescence imaging of chemically functionalized multi-walled carbon nanotubes in cells and solid tumors. Chemical Communications 2015, 51, (45), 9366-9369.

63.       Rubio, N.; Mei, K.-C.; Klippstein, R.; Costa, P. M.; Hodgins, N.; Wang, J. T.-W.; Festy, F.; Abbate, V.; Hider, R. C.; Chan, K. L. A.; Al-Jamal, K. T., Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide. ACS Applied Materials & Interfaces 2015, 7, (34), 18920-18923.

64.       Sado, D. M.; Maestrini, V.; Piechnik, S. K.; Banypersad, S. M.; White, S. K.; Flett, A. S.; Robson, M. D.; Neubauer, S.; Ariti, C.; Arai, A.; Kellman, P.; Yamamura, J.; Schoennagel, B. P.; Shah, F.; Davis, B.; Trompeter, S.; Walker, M.; Porter, J.; Moon, J. C., Noncontrast myocardial T-1 mapping using cardiovascular magnetic resonance for iron overload. Journal of Magnetic Resonance Imaging 2015, 41, (6), 1505-1511.

65.       Schnell, S.; Bawa-Allah, K.; Otitoloju, A.; Hogstrand, C.; Miller, T. H.; Barron, L. P.; Bury, N. R., Environmental monitoring of urban streams using a primary fish gill cell culture system (FIGCS). Ecotoxicology and Environmental Safety 2015, 120, 279-285.

66.       Shooter, C.; McKenzie, T.; Oakley, M.; Jacques, T.; Clark, B.; Thein, S. L., First reported duplication of the entire beta globin gene cluster causing an unusual sickle cell trait phenotype. British Journal of Haematology 2015, 170, (1), 128-131.

67.       Shooter, C.; Rooks, H.; Thein, S. L.; Clark, B., Next Generation Sequencing Identifies a Novel Rearrangement in the HBB Cluster Permitting to-the-Base Characterization. Human Mutation 2015, 36, (1), 142-150.

68.       Stott, L. C.; Schnell, S.; Hogstrand, C.; Owen, S. F.; Bury, N. R., A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: Evidence for passive and facilitated transport. Aquatic Toxicology 2015, 159, 127-137.

69.       Suaifan, G.; Shehadeh, M. B.; Darwish, R. M.; Al-Ijel, H.; Abbate, V., Design, Synthesis and in Vivo Evaluation of Novel Glycosylated Sulfonylureas as Antihyperglycemic Agents. Molecules 2015, 20, (11), 20063-20078.

70.       Taher, A. T.; Porter, J. B.; Viprakasit, V.; Kattamis, A.; Chuncharunee, S.; Sutcharitchan, P.; Siritanaratkul, N.; Origa, R.; Karakas, Z.; Habr, D.; Zhu, Z. W.; Cappellini, M. D., Defining serum ferritin thresholds to predict clinically relevant liver iron concentrations for guiding deferasirox therapy when MRI is unavailable in patients with non-transfusion-dependent thalassaemia. British Journal of Haematology 2015, 168, (2), 284-290.

71.       Vidler, J. B.; Gardner, K.; Amenyah, K.; Mijovic, A.; Thein, S. L., Delayed haemolytic transfusion reaction in adults with sickle cell disease: a 5-year experience. British Journal of Haematology 2015, 169, (5), 746-753.

72.       Ward, R. J.; Dexter, D. T.; Crichton, R. R., Ageing, neuroinflammation and neurodegeneration. Frontiers in bioscience (Scholar edition) 2015, 7, 189-204.

73.       Ward, R. J.; Dexter, D. T.; Crichton, R. R., Neurodegenerative diseases and therapeutic strategies using iron chelators. Journal of Trace Elements in Medicine and Biology 2015, 31, 267-273.

74.       Zhou, T.; Hider, R. C.; Kong, X., Mode of iron(iii) chelation by hexadentate hydroxypyridinones. Chemical Communications 2015, 51, (26), 5614-5617.

75.       Zhou, Y. J.; Kong, X. L.; Li, J. P.; Ma, Y. M.; Hider, R. C.; Zhou, T., Novel 3-hydroxypyridin-4-one hexadentate ligand-based polymeric iron chelator: synthesis, characterization and antimicrobial evaluation. Medchemcomm 2015, 6, (9), 1620-1625.

76.       Zhou, Y.-J.; Liu, M.-S.; Osamah, A. R.; Kong, X.-L.; Alsam, S.; Battah, S.; Xie, Y.-Y.; Hider, R. C.; Zhou, T., Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: Design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains. European Journal of Medicinal Chemistry 2015, 94, (0), 8-21.

77.       Zhu, C. F.; Battah, S.; Kong, X. L.; Reeder, B. J.; Hider, R. C.; Zhou, T., Design, synthesis and biological evaluation of 5-aminolaevulinic acid/3-hydroxypyridinone conjugates as potential photodynamic therapeutical agents. Bioorganic & Medicinal Chemistry Letters 2015, 25, (3), 558-561.






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