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Biomedical Engineering & Imaging Sciences

Predicting Atrial Mechanics after Ablation of Atrial Fibrillation

To start
June 2021, October 2021, February 2022

Award
Fully funded 3.5 year Full-time PhD studentship (including home tuition fees, annual stipend and consumables)


School
Biomedical Engineering & Imaging Sciences

Supervisors
Prof Steven Niederer
Dr Martin Bishop

Sponsor
EPSRC Doctoral Training Partnership (DTP)


Project code
DTP 20_02

Stipend
ca £17,000 + generous consumables budget


Project summary
Atrial fibrillation (AF) is the most common arrhythmia, resulting in chaotic activation of the atria and deterioration of cardiac function. AF can be treated either pharmacologically to stop or mitigate the effects of AF, by ablation to isolate or remove aberrant tissue and revert the heart to normal sinus rhythm, or by ablation of the AV node and implanting a pacing device to remove the effects of AF on the ventricles. These treatments have different impacts on atrial electrophysiology, heart rate speed and regularity, and ventricular and atrial mechanics. This PhD will use a combination of image analysis and simulation to create a virtual cohort of four chamber heart models. The cohort will be used first to investigate how anatomical, material properties and loading conditions determine the response to each of the AF treatments, and second to determine the contribution of atrial mechanics and the speed and regularity of the heart rate on ventricular function.

Eligibility
Eligibility criteria for the June 2021 intake: Only home UK or EU/EEA candidates fulfilling the 3-year UK residency requirement are eligible for the EPSRC DTP studentships. EU/EEA applicants are only eligible for a full studentship if they have lived, worked or studied in the UK for 3 years prior to the funding commencing.

Eligibility criteria for start dates in October 2021 and February 2022
Candidates who meet the eligibility requirements for Home Fee status will be eligible to apply for this project. Home students will be eligible for a full UKRI award, including fees and stipend, if they satisfy the UKRI criteria below, including residency requirements. To be classed as a Home student, candidates must meet the following criteria:

  •  be a UK National (meeting residency requirements), or
  •  have settled status, or
  •  have pre-settled status (meeting residency requirements), or
  •  have indefinite leave to remain or enter.

How to apply
Please submit an application for the Biomedical Engineering and Imaging Science Research MPhil/PhD (Full-time) programme using the King’s Apply system Please include the following with your application:

  • A PDF copy of your CV should be uploaded to the Employment History section.
  • A PDF copy of your personal statement using this template should be uploaded to the Supporting statement section.
  • Funding information: Please choose Option 5 “I am applying for a funding award or scholarship administered by King’s College London” and under “Award Scheme Code or Name” enter BMEIS_DTP. Failing to include this code might result in you not being considered for this funding scheme.

Application closing date
2 April 2021 (Applications may close early if a suitable candidate is found)

Contact information for enquiries
Please email Prof Steven Niederer steven.niederer@kcl.ac.uk

 

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