Vitamin D has a pivotal role in the mineralisation of bones and teeth.
Vitamin D is closely associated with calcium, since it controls bone mineralisation through the regulation of calcium and phosphorus homeostasis.
Additionally, vitamin D has critical physiological roles across many body functions and systems, not just through bones and teeth. These include in cell proliferation and differentiation, regulation of the innate and adaptive immune systems, preventive effects on cardiovascular, neurodegenerative diseases, oxidative stress reduction, cognitive decline and depression, progression of skeletal and non-skeletal diseases and against risk for malignant neoplasms.
The full entry for vitamin D is undergoing validation and will be added soon.
Braithwaite, Crozier, D’Angelo, Prentice A, ….Jones KS. and the MAVIDOS Trial Group. The Effect of Vitamin D Supplementation on Hepcidin, Iron Status, and Inflammation in Pregnant Women in the United Kingdom. Nutrients 2019, 11, 190. doi:10.3390/nu11010190
Hengist, A. , Perkin, O. , Gonzalez, J. T., Betts, J. A., Hewison, M. , Manolopoulos, K. N., Jones, K. S., Koulman, et al. Mobilising vitamin D from adipose tissue: The potential impact of exercise. Nutr Bull. 2019. doi:10.1111/nbu.12369
Roth, Abrams, Aloia, ….Jones, K. S. et al. Global prevalence and disease burden of vitamin D deficiency: a roadmap for action in low‐ and middle‐income countries. Ann. N.Y. Acad. Sci., 2018. 1430: 44-79. doi:10.1111/nyas.13968