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King’s People

Dr Aileen King

Academics

Senior Lecturer in Pharmacology

School Academic Lead, Development, Diversity & Inclusion.

Contact details

Biography

Aileen received her undergraduate degree in Biomedical Sciences from the University of Ulster, Coleraine, Northern Ireland. After her undergraduate degree, she did her PhD in Medical Sciences at Uppsala University, Sweden. She carried out postdoctoral studies at Joslin Diabetes Center, Harvard University for three years before returning to Sweden for a short spell before starting an RCUK fellowship at King’s College, London in 2006. In January 2011, she took up a position as Lecturer in Pharmacology at King’s College London and has been a Senior Lecturer since 2013. Her current main research interest is understanding how male and females respond differently to ER stress in pancreatic beta cells. She is a member of the Pharmacology and Therapeutics teaching department where she holds the role of senior tutor. Her teaching interests include teaching in vivo skills and statistics.

Latest publications

Modulation of Rab7a-mediated growth factor receptor trafficking inhibits islet beta cell apoptosis and autophagy under conditions of metabolic stress
Hewawasam, N. V., Lhaf, F., Taylor, H. A., Viloria, K., Austin, A., King, A., Jones, P., Jones, L., Turner, M. D. & Hill, N. J., 1 Dec 2020, In : Scientific Reports. 10, 1, 15741. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-020-72939-y
The KINGS Ins2+/G32S Mouse: a Novel Model of Beta Cell Endoplasmic Reticulum Stress and Human Diabetes
Austin, A., Daniels Gatward, L., Cnop, M., Santos, G., Andersson, D., Sharp, S., Gentry, C., Bevan, S., Jones, P. & King, A., 29 Sep 2020, In : Diabetes. db200570. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.2337/db20-0570
Optimizing beta cell function through mesenchymal stromal cell mediated mitochondria transfer
Rackham, C. L., Hubber, E. L., Czajka, A., Malik, A. N., King, A. JF. & Jones, P. M., Apr 2020, In : Stem Cells. 38, 8, p. 574-584 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1002/stem.3134
Assessing Islet Transplantation Outcome in Mice
King, A. J. F. & Rackham, C. L., 1 Jan 2020, Methods in Molecular Biology. Stocker, C. (ed.). Vol. 2076. p. 265-280 16 p. (Methods in molecular biology (Clifton, N.J.)). Research output: Chapter in Book/Report/Conference proceeding - Chapter. DOIs: https://doi.org/10.1007/978-1-4939-9882-1_16
Continuous Glucose Monitoring in Conscious Unrestrained Mice
King, A. J. F., Kennard, M. R. & Nandi, M., 1 Jan 2020, In : Methods in molecular biology (Clifton, N.J.). 2128, p. 225-239 15 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1007/978-1-0716-0385-7_16
Practical Considerations when Using Mouse Models of Diabetes
King, A. J. F., Daniels Gatward, L. F. & Kennard, M. R., 1 Jan 2020, In : Methods in molecular biology (Clifton, N.J.). 2128, p. 1-10 10 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1007/978-1-0716-0385-7_1
Use of Streptozotocin in Rodent Models of Islet Transplantation
King, A. J. F., Estil Les, E. & Montanya, E., 1 Jan 2020, In : Methods in molecular biology (Clifton, N.J.). 2128, p. 135-147 13 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1007/978-1-0716-0385-7_10
Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors
Segal, J. M., Kent, D. H., Wesche, D., Ng, S. S., Quake, S., Serra, M., Nakauchi, H., Rashid, S. T., King, A., Oules, B., Kar, G., Emerton, G., Blackford, S., Darmanis, S., Miquel, R., Luong, T. V., Yamamoto, R., Bonham, A., Jassem, W., Heaton, N. & 3 others, Vigilante, A., Sancho, R. & Teichmann, S. A., 24 Jun 2019, (Accepted/In press) In : Nature Communications. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41467-019-11266-x
Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy
Blackford, S. J. I., Ng, S. S., Segal, J. M., King, A., Austin, A. L. F., Kent, D. H., Moore, J., Sheldon, M., Ilic, D., Dhawan, A., Mitry, R. & Rashid, S. T., Feb 2019, In : Stem cells translational medicine. 8, 2, p. 124-137 14 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1002/sctm.18-0084
Characterization of the Effects of Mesenchymal Stromal Cells on Mouse and Human Islet Function
Arzouni, A. A., Vargas-Seymour, A., Dhadda, P. K., Rackham, C. L., Huang, G. C., Choudhary, P., King, A. J. F. & Jones, P. M., 2019, In : Stem cells translational medicine. 8, 9, p. 935-944 10 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1002/sctm.19-0023

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