Dr Annapurna Vyakarnam Academics Affiliates School Academic Lead (International) Reader in Microbial Immunology . Visiting Professor, Indian Institute of Science, India. Contact details anna.vyakarnam@kcl.ac.uk
HIV infection of latent tuberculosis subjects skews a balanced Mtb-specific Th17 response to a proinflammatory Th17 profile that is independent of cellular viral load: HIV alters the nature of the Mtb-specific Th17 response Vyakarnam, A., 1 Oct 2020, (Accepted/In press) In : Cell Reports. p. 1 87 p., CELL-REPORTS-D-20-02256R1. Research output: Contribution to journal - Article Innate immune mechanisms to oral pathogens in oral mucosa of HIV-infected individuals Weinberg, A., Tugizov, S., Pandiyan, P., Jin, G., Rakshit, S., Vyakarnam, A. & Naglik, J. R., 1 Sep 2020, In : Oral Diseases. 26, S1, p. 69-79 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/odi.13470 Emerging patterns of regulatory T cell function in tuberculosis Ahmed, A. & Vyakarnam, A., 1 Jan 2020, (Accepted/In press) In : Clinical and Experimental Immunology. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1111/cei.13488 BCG revaccination boosts adaptive polyfunctional Th1/Th17 and innate effectors in IGRA+ and IGRA- Indian adults Rakshit, S., Ahmed, A., Adiga, V., Sundararaj, B. K., Sahoo, P. N., Kenneth, J., D'Souza, G., Bonam, W., Johnson, C., Franken, K. L., Ottenhoff, T. H., Finak, G., Gottardo, R., Stuart, K. D., De Rosa, S. C., McElrath, M. J. & Vyakarnam, A., 2019, In : JCI Insight. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1172/jci.insight.130540 Evidence for Highly Variable, Region-Specific Patterns of T-Cell Epitope Mutations Accumulating in Mycobacterium tuberculosis Strains Ramaiah, A., Nayak, S., Rakshit, S., Manson, A. L., Abeel, T., Shanmugam, S., Sahoo, P. N., John, A. J. U. K., Sundaramurthi, J. C., Narayanan, S., D'souza, G., Von Hoegen, P., Ottenhoff, T. H. M., Swaminathan, S., Earl, A. M. & Vyakarnam, A., 2019, In : Frontiers in Immunology. 10, 1 p., 195. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.3389/fimmu.2019.00195 Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis Ahmed, A., Adiga, V., Nayak, S., Uday Kumar, J. A. J., Dhar, C., Sahoo, P. N., Sundararaj, B. K., Souza, G. D., Vyakarnam, A. & Lewinsohn, D. M. (ed.), 19 Sep 2018, In : PLoS Pathogens. 14, 9, e1007289. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.ppat.1007289 Deep sequencing of near full-length HIV-1 genomes from plasma identifies circulating subtype C and infrequent occurrence of AC recombinant form in Southern India Alampalli, S. V., Thomson, M. M., Sampathkumar, R., Sivaraman, K., U. K. J., A. J., Dhar, C., D. Souza, G., Berry, N., Vyakarnam, A. & Paxton, W. A. (ed.), 8 Dec 2017, In : PL o S One . 12, 12, p. e0188603 14 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.pone.0188603 Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10+ Th17 CD4 T-cells differentiate latent from active tuberculosis Rakshit, S., Adiga, V., Nayak, S., Sahoo, P. N., Sharma, P. K., Van Meijgaarden, K. E., Uk J., A. J., Dhar, C., Souza, G. D., Finak, G., De Rosa, S. C., Ottenhoff, T. H. M. & Vyakarnam, A., 20 Sep 2017, In : Scientific Reports. 7, 1, 15 p., 11948. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-017-10773-5 Unbiased Identification of Blood-based Biomarkers for Pulmonary Tuberculosis by Modeling and Mining Molecular Interaction Networks Sambarey, A., Devaprasad, A., Mohan, A., Ahmed, A., Nayak, S., Swaminathan, S., D'Souza, G., Jesuraj, A., Dhar, C., Babu, S., Vykarnam, A. & Chandra, N., 21 Dec 2016, In : EBioMedicine. 15, p. 112-126 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.ebiom.2016.12.009 Cathepsin-L and Transglutaminase Dependent Processing of ps20: A novel Mechanism for ps20 Regulation via ECM Cross-Linking Hickman, O. J., Dasgupta, P., Galustian, C., Smith, R. A. & Vyakarnam, A., Sep 2016, In : Biochemistry and Biophysics Reports . 7, p. 328-337 10 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.bbrep.2016.06.010 View all publications