Dr Annapurna Vyakarnam Academics Affiliates Reader in Microbial Immunology School Academic Lead, International. Contact details anna.vyakarnam@kcl.ac.uk
HIV Skews a Balanced Mtb-Specific Th17 Response in Latent Tuberculosis Subjects to a Pro-inflammatory Profile Independent of Viral Load Rakshit, S., Hingankar, N., Alampalli, S. V., Adiga, V., Sundararaj, B. K., Sahoo, P. N., Finak, G., Uday Kumar J, A. J., Dhar, C., D'Souza, G., Virkar, R. G., Ghate, M., Thakar, M. R., Paranjape, R. S., De Rosa, S. C., Ottenhoff, T. H. M. & Vyakarnam, A., 1 Dec 2020, In : Cell Reports. 33, 9, 108451. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.celrep.2020.108451 Emerging patterns of regulatory T cell function in tuberculosis Ahmed, A. & Vyakarnam, A., Dec 2020, In : Clinical and Experimental Immunology. 202, 3, p. 273-287 15 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1111/cei.13488 HIV infection of latent tuberculosis subjects skews a balanced Mtb-specific Th17 response to a proinflammatory Th17 profile that is independent of cellular viral load: HIV alters the nature of the Mtb-specific Th17 response Vyakarnam, A., 1 Oct 2020, (Accepted/In press) In : Cell Reports. p. 1 87 p., CELL-REPORTS-D-20-02256R1. Research output: Contribution to journal - Article Innate immune mechanisms to oral pathogens in oral mucosa of HIV-infected individuals Weinberg, A., Tugizov, S., Pandiyan, P., Jin, G., Rakshit, S., Vyakarnam, A. & Naglik, J. R., 1 Sep 2020, In : Oral Diseases. 26, S1, p. 69-79 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/odi.13470 Evidence for Highly Variable, Region-Specific Patterns of T-Cell Epitope Mutations Accumulating in Mycobacterium tuberculosis Strains Ramaiah, A., Nayak, S., Rakshit, S., Manson, A. L., Abeel, T., Shanmugam, S., Sahoo, P. N., John, A. J. U. K., Sundaramurthi, J. C., Narayanan, S., D'souza, G., Von Hoegen, P., Ottenhoff, T. H. M., Swaminathan, S., Earl, A. M. & Vyakarnam, A., 13 Feb 2019, In : Frontiers in Immunology. 10, 0, 18 p., 195. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.3389/fimmu.2019.00195 BCG revaccination boosts adaptive polyfunctional Th1/Th17 and innate effectors in IGRA+ and IGRA- Indian adults Rakshit, S., Ahmed, A., Adiga, V., Sundararaj, B. K., Sahoo, P. N., Kenneth, J., D'Souza, G., Bonam, W., Johnson, C., Franken, K. L., Ottenhoff, T. H., Finak, G., Gottardo, R., Stuart, K. D., De Rosa, S. C., McElrath, M. J. & Vyakarnam, A., 2019, In : JCI Insight. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1172/jci.insight.130540 Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis Ahmed, A., Adiga, V., Nayak, S., Uday Kumar, J. A. J., Dhar, C., Sahoo, P. N., Sundararaj, B. K., Souza, G. D., Vyakarnam, A. & Lewinsohn, D. M. (ed.), 19 Sep 2018, In : PLoS Pathogens. 14, 9, p. 1-35 35 p., e1007289. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.ppat.1007289 Deep sequencing of near full-length HIV-1 genomes from plasma identifies circulating subtype C and infrequent occurrence of AC recombinant form in Southern India Alampalli, S. V., Thomson, M. M., Sampathkumar, R., Sivaraman, K., U. K. J., A. J., Dhar, C., D. Souza, G., Berry, N., Vyakarnam, A. & Paxton, W. A. (ed.), 8 Dec 2017, In : PL o S One . 12, 12, p. e0188603 14 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.pone.0188603 Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10+ Th17 CD4 T-cells differentiate latent from active tuberculosis Rakshit, S., Adiga, V., Nayak, S., Sahoo, P. N., Sharma, P. K., Van Meijgaarden, K. E., Uk J., A. J., Dhar, C., Souza, G. D., Finak, G., De Rosa, S. C., Ottenhoff, T. H. M. & Vyakarnam, A., 20 Sep 2017, In : Scientific Reports. 7, 1, 15 p., 11948. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-017-10773-5 Unbiased Identification of Blood-based Biomarkers for Pulmonary Tuberculosis by Modeling and Mining Molecular Interaction Networks Sambarey, A., Devaprasad, A., Mohan, A., Ahmed, A., Nayak, S., Swaminathan, S., D'Souza, G., Jesuraj, A., Dhar, C., Babu, S., Vykarnam, A. & Chandra, N., 21 Dec 2016, In : EBioMedicine. 15, p. 112-126 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.ebiom.2016.12.009 View all publications