Chad Swanson Dr Chad Swanson Academics Supervisors Lecturer Research subject areas Immunology Contact details chad.swanson@kcl.ac.uk
TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction Ribeiro Galao, R. P., Wilson, H., Schierhorn, K., Debeljak, F., Bodmer, B., Goldhill, D., Hoenen, T., Wilson, S. J., Swanson, C. & Neil, S., 19 May 2022, In: Plos pathogens. 18, 5, e1010530. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1371/journal.ppat.1010530 Minimal impact of ZAP on lentiviral vector production and transduction efficiency Sertkaya, H., Hidalgo Lumbreras, L., Ficarelli, M., Kmiec, D., Signell, A., Ali, S., Parker, H., Wilson, H., Neil, S., Malim, M., Vink, C. A. & Swanson, C., 10 Dec 2021, In: Molecular Therapy - Methods and Clinical Development. 23, p. 147-157 11 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.omtm.2021.08.008 HIV-1 sequences in lentiviral vector genomes can be substantially reduced without compromising transduction efficiency Sertkaya, H., Ficarelli, M., Sweeney, N. P., Parker, H., Vink, C. A. & Swanson, C. M., Dec 2021, In: Scientific Reports. 11, 1, 12067. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-021-91309-w S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies Kmiec, D., Lista Brotos, M., Ficarelli, M., Swanson, C. & Neil, S., Oct 2021, In: Plos pathogens. 17, 10, e1009726. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/doi.org/10.1371/journal.ppat.1009726 Targeted Restriction of Viral Gene Expression and Replication by the ZAP Antiviral System Ficarelli, M., Neil, S. J. D. & Swanson, C. M., 29 Sep 2021, In: Annual Review of Virology. 8, 1, p. 265-283 19 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1146/annurev-virology-091919-104213 HIV-1 vpr induces widespread transcriptomic changes in CD4+ T cells early postinfection Bauby, H., Ward, C. C., Hugh-White, R., Swanson, C. M., Schulz, R., Goujon, C. & Malima, M. H., Jun 2021, In: Mbio. 12, 3, e01369-21. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1128/mBio.01369-21 The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2 Winstone, H., Lista, M. J., Reid, A., Bouton, C., Pickering, S., Ribeiro Galao, R. P., Kerridge, C., Doores, K., Swanson, C. & Neil, S., 12 Apr 2021, In: Journal of virology. 95, 9, e02422-20. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1128/JVI.02422-20 Utilising mass cytometry with CD45 barcoding and standardised leucocyte phenotyping for immune trajectory assessment in critically ill patients Fish, M., Ellis, R., Bishop, C., Todd, K., Petrov, N., Singer, M., Swanson, C. M. & Shankar-Hari, M., Apr 2021, In: British Journal of Anaesthesia. 126, 4, p. e149-e152 Research output: Contribution to journal › Letter › peer-review. DOIs: https://doi.org/10.1016/j.bja.2021.01.006 Sars-cov-2 is restricted by zinc finger antiviral protein despite preadaptation to the low-cpg environment in humans Nchioua, R., Kmiec, D., Müller, J. A., Conzelmann, C., Groß, R., Swanson, C. M., Neil, S. J. D., Stenger, S., Sauter, D., Münch, J., Sparrer, K. M. J. & Kirchhoff, F., 1 Sep 2020, In: Mbio. 11, 5, p. 1-19 19 p., e01930-20. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1128/mBio.01930-20 CpG dinucleotides inhibit HIV-1 replication through zinc finger antiviral protein (ZAP)-dependent and -independent mechanisms) Ficarelli, M., Antzin Anduetza, I., Hugh-White, R. J., Firth, A., Sertkaya, H., Wilson, H. D., Neil, S. J. D., Schulz, R. S. D. & Swanson, C. M., 28 Feb 2020, In: Journal of virology. Research output: Contribution to journal › Article › peer-review View all publications
9 July 2019 Scientists identify new virus-killing protein A newly identified protein called KHNYN teams up with ZAP, a known virus-killing protein, to destroy…