Dr Chiappini Dr Ciro Chiappini Academics Supervisors Senior Lecturer in Nanomaterials and Biointerfaces Associate Dean for Impact. Contact details 020 7188 8029 ciro.chiappini@kcl.ac.uk
Biomaterials-based approaches to model embryogenesis Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection The art and science of collaboration in bioengineering research Nanoneedles enable spatiotemporal lipidomics of living tissues Nanoneedle-Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T-Cells Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa Porous and non-porous nanostructures Lithiated Silicon Nanoprojection array and a method for fabricating a nanoprojection array The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows The association of silicon microparticles with endothelial cells in drug delivery to the vasculature In vivo evaluation of safety of nanoporous silicon carriers following single and multiple dose intravenous administrations in mice Size and shape effects in the biodistribution of intravascularly injected particles Mesoporous silicon particles as intravascular drug delivery vectors: Fabrication, in-vitro, and in-vivo assessments Mesoporous silicon-PLGA composite microspheres for the double controlled release of biomolecules for orthopedic tissue engineering Silicon nanoneedles for drug delivery MACE silicon nanostructures Biophysical Regulations of Epigenetic State and Notch Signaling in Neural Development Using Microgroove Substrates Spatially-Resolved Organoid Transfection by Porous Silicon-Mediated Optoporation Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection Opto-Lipidomics of Tissues Lithiated porous silicon nanowires stimulate periodontal regeneration CRISPR/Cas-Assisted Nanoneedle Sensor for Adenosine Triphosphate Detection in Living Cells Nanoscaffolds for neural regenerative medicine Two-Photon Light Trigger siRNA Transfection of Cancer Cells Using Non-Toxic Porous Silicon Nanoparticles Nanoneedles Induce Targeted siRNA Silencing of p16 in the Human Corneal Endothelium A method for reproducible high-resolution imaging of 3D cancer cell spheroids Porcine Organotypic Epicardial Slice Protocol: A Tool for the Study of Epicardium in Cardiovascular Research Biointerface design for vertical nanoprobes The start-ups taking nanoneedles into the clinic Nanoneedle devices for biomedicine Hybrid confocal Raman endomicroscopy for morpho-chemical tissue characterization Axonal Length Determines Distinct Homeostatic Phenotypes in Human iPSC Derived Motor Neurons on a Bioengineered Platform Epicardial slices: an innovative 3D organotypic model to study epicardial cell physiology and activation Tutorial: using nanoneedles for intracellular delivery Nanomedicine Approaches to Negotiate Local Biobarriers for Topical Drug Delivery Mechanically directing the differention and organisation of stem cell to recapitulate key liver function Harvesting biomolecules from tissue by porous silicon nanoneedles Biomaterials-based approaches to model embryogenesis Inorganic nanotheranostic platforms for rapid and reliable molecular profiling of diseases Nano-particles for biomedical applications Immunogold FIB-SEM: Combining Volumetric Ultrastructure Visualization with 3D Biomolecular Analysis to Dissect Cell–Environment Interactions A quantitative approach for determining the role of geometrical constraints when shaping mesenchymal condensations Porous Silicon Nanoneedles Modulate Endocytosis to Deliver Biological Payloads Micro-scaled topographies direct differentiation of human epidermal stem cells MACE silicon nanostructures Porous silicon microneedles and nanoneedles Correlated Heterospectral Lipidomics for Biomolecular Profiling of Remyelination in Multiple Sclerosis Surface Presentation of Functional Peptides in Solution Determines Cell Internalization Efficiency of TAT Conjugated Nanoparticles Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization View all publications
16 June 2025 Tens of millions of nanoneedles could replace painful cancer biopsies A patch containing tens of millions of microscopic nanoneedles could soon replace traditional…