Serio Lab
We are interested in combining bioengineering, advanced imaging techniques and stem cell modelling to create new modelling platforms dedicated to Neural Circuit Engineering (NCE) and Neurotechnology, and use them to obtain novel insights into how the nervous system functions in health and disease. We focus. By creating novel bio-mimetic neural tissue engineering platforms we aim to shed light on how neuronal circuitry develops and connects different areas of the nervous system and other organs sometimes across vast distances. We aim to tackle both fundamental questions in the field of neurobiology (e.g. how neurons sense their own length and how decisional processes are made in the formation of neural circuits, what is the relationship between shape and function in glial cells), as well as open questions on the mechanisms leading to neurodegenerative disorders (e.g. how are certain types of neurons vulnerable to diseases but not others, what is the role of cellular shape and response to stress in glial cells), pushing the edge of what is currently achievable with stem cell modelling.
Serio Lab