Franca Fraternalli Professor Franca Fraternali Academics Supervisors Professor in Bioinformatics & Computational Biology Head of Department, Randall Centre for Cell & Molecular Biophysics. Research subject areas Biomedical and life sciences Contact details franca.fraternali@kcl.ac.uk +44 (0) 20 7848 6843
Allosteric Regulation of the Soluble Epoxide Hydrolase by Nitro Fatty Acids: a Combined Experimental and Computational Approach: Allosteric regulation of hsEH by nitro fatty acids Qiu, Q., Abis, G., Mattingly-Peck, F., Lynham, S., Fraternali, F. & Conte, M. R., 15 Sep 2022, In: Journal of Molecular Biology. 434, 17, 167600. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jmb.2022.167600 Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling Kausas, M., Esposito, D., Rittinger, K. & Fraternali, F., 8 Sep 2022, In: Scientific Reports. 12, 1, p. 15201 1 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-022-18890-6 Editorial overview: Modern and future methods for studying macromolecular assemblies in action Brown, A. & Fraternali, F., Aug 2022, In: Current Opinion in Structural Biology. 75, 102438. Research output: Contribution to journal › Editorial › peer-review. DOIs: https://doi.org/10.1016/j.sbi.2022.102438 Profiling the Site of Protein CoAlation and Coenzyme A Stabilization Interactions Tossounian, M. A., Baczynska, M., Dalton, W., Newell, C., Ma, Y., Das, S., Semelak, J. A., Estrin, D. A., Filonenko, V., Trujillo, M., Peak-Chew, S. Y., Skehel, M., Fraternali, F., Orengo, C. & Gout, I., Jul 2022, In: Antioxidants. 11, 7, 1362. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/antiox11071362 Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus Stewart, A., Sinclair, E., Ng, J. C. F., O’Hare, J. S., Page, A., Serangeli, I., Margreitter, C., Orsenigo, F., Longman, K., Frampas, C., Costa, C., Lewis, H. M., Kasar, N., Wu, B., Kipling, D., Openshaw, P. J. M., Chiu, C., Baillie, J. K., Scott, J. T., Semple, M. G. & 3 others, Bailey, M. J., Fraternali, F. & Dunn-Walters, D. K., 3 May 2022, In: Frontiers in Immunology. 13, 807104. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2022.807104 Sulfated Progesterone Metabolites That Enhance Insulin Secretion Via Trpm3 are Reduced in Serum From Women with Gestational Diabetes Mellitus Fan, H. M., Mitchell, A. L., Bellafante, E., McIlvride, S., Primicheru, L. I., Giorgi, M., Eberini, I., Syngelaki, A., Lövgren-Sandblom, A., Jones, P., McCance, D., Sukumar, N., Periyathambi, N., Weldeselassie, Y., Hunt, K. F., Nicolaides, K. H., Andersson, D., Bevan, S., Seed, P. T., Bewick, G. A. & 5 others, Bowe, J. E., Fraternali, F., Saravanan, P., Marschall, H. & Williamson, C., 1 Apr 2022, In: Diabetes. 71, 4, p. 837-852 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.2337/db21-0702 Editorial: Understanding and Engineering Antibody-Superantigen Interactions Gan, S. K. E., Derrick, J. P. & Fraternali, F., 9 Feb 2022, In: Frontiers in Immunology. 13, 857339. Research output: Contribution to journal › Editorial › peer-review. DOIs: https://doi.org/10.3389/fimmu.2022.857339 PDBe-KB: collaboratively defining the biological context of structural data PDBe-KB consortium , 2022, In: Nucleic Acids Research. 50, D1, p. D534-D542 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/nar/gkab988 Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation Vickers, A., Tewary, M., Laddach, A., Poletti, M., Salameti, V., Fraternali, F., Danovi, D. & Watt, F. M., 9 Nov 2021, In: Stem cell reports. 16, 11, p. 2628-2641 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.stemcr.2021.09.017 Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer Harris, R. J., Cheung, A., Ng, J. C. F., Laddach, R., Chenoweth, A. M., Crescioli, S., Fittall, M., Dominguez-Rodriguez, D., Roberts, J., Levi, D., Liu, F., Alberts, E., Quist, J., Santaolalla, A., Pinder, S. E., Gillett, C., Hammar, N., Irshad, S., van Hemelrijck, M., Dunn-Walters, D. K. & 7 others, Fraternali, F., Spicer, J. F., Lacy, K. E., Tsoka, S., Grigoriadis, A., Tutt, A. N. J. & Karagiannis, S. N., 15 Aug 2021, In: Cancer Research. 81, 16, p. 4290-4304 15 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1158/0008-5472.CAN-20-3773, https://doi.org/10.1158/0008-5472.CAN-20-3773 View all publications
1 December 2021 King's College London joins ELIXIR-UK By joining the intergovernmental organisation King’s will be more meaningfully involved in…