Professor Franca Fraternali Academics Professor in Bioinformatics & Computational Biology Head of Department, Randall Centre for Cell & Molecular Biophysics. Contact details franca.fraternali@kcl.ac.uk +44 (0) 20 7848 6843
Molecular Simulations Guidelines for Biological Nanomaterials: From Peptides to Membranes Marzuoli, I. & Fraternali, F., 1 Jan 2021, In: Methods in molecular biology (Clifton, N.J.). 2208, p. 81-100 20 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1007/978-1-0716-0928-6_6 A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex—An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface Nichols, C., Ng, J., Keshu, A., Fraternali, F. & De Nicola, G. F., 14 Dec 2020, In: Frontiers in Pharmacology. 11, 615211. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.3389/fphar.2020.615211 SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals Lam, S. D., Bordin, N., Waman, V. P., Scholes, H. M., Ashford, P., Sen, N., van Dorp, L., Rauer, C., Dawson, N. L., Pang, C. S. M., Abbasian, M., Sillitoe, I., Edwards, S. J. L., Fraternali, F., Lees, J. G., Santini, J. M. & Orengo, C. A., 1 Dec 2020, In: Scientific Reports. 10, 1, 16471. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1038/s41598-020-71936-5 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α-TAB1 Complexes Nichols, C., Ng, J., Keshu, A., Kelly, G., Conte, M. R., Marber, M. S., Fraternali, F. & De Nicola, G. F., 23 Jul 2020, In: Journal of Medicinal Chemistry. 63, 14, p. 7559-7568 10 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1021/acs.jmedchem.0c00403 The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition Kelly, J. R., Martini, S., Brownlow, N., Joshi, D., Federico, S., Jamshidi, S., Kjaer, S., Lockwood, N., Rahman, K. M., Fraternali, F., Parker, P. J. & Soliman, T. N., 13 Mar 2020, In: Nature Communications. 11, p. 1-14 1396. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1038/s41467-020-15163-6 Symmetry-breaking transitions in the early steps of protein self-assembly La Rosa, C., Condorelli, M., Compagnini, G., Lolicato, F., Milardi, D., Do, T. N., Karttunen, M., Pannuzzo, M., Ramamoorthy, A., Fraternali, F., Collu, F., Rezaei, H., Strodel, B. & Raudino, A., 1 Mar 2020, In: European Biophysics Journal. 49, 2, p. 175-191 17 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1007/s00249-020-01424-1 Engineering Chirally Blind Protein Pseudocapsids into Antibacterial Persisters Kepiro, I. E., Marzuoli, I., Hammond, K., Ba, X., Lewis, H., Shaw, M., Gunnoo, S. B., De Santis, E., ÅapiÅ„ska, U., Pagliara, S., Holmes, M. A., Lorenz, C. D., Hoogenboom, B. W., Fraternali, F. & Ryadnov, M. G., 25 Feb 2020, In: ACS Nano. 14, 2, p. 1609-1622 14 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1021/acsnano.9b06814 Structure and Dynamics of Nanoconfined Water between Surfactant Monolayers Ziolek, R. M., Fraternali, F., Dhinojwala, A., Tsige, M. & Lorenz, C. D., 14 Jan 2020, In: Langmuir. 36, 1, p. 447-455 9 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1021/acs.langmuir.9b03130 PDBE-KB: A community-driven resource for structural and functional annotations PDBe-KB consortium , 1 Jan 2020, In: Nucleic Acids Research. 48, p. D344-D353 Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1093/nar/gkz853 Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells Jimeno, R., Lebrusant-Fernandez, M., Margreitter, C., Lucas, B., Veerapen, N., Besra, G., Fraternali, F., Spencer, J., Anderson, G. & Barral, P., 24 Dec 2019, In: eLife. 8, e51663. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.7554/eLife.51663 View all publications
15 October 2019 Professor Fraternali awarded funding to study how antibodies switch their function Professor Franca Fraternali has been awarded a grant from the Biotechnology and Biological Sciences…