Professor Leonie Taams Academics Supervisors Head of the School of Immunology & Microbial Sciences Professor of Immune Regulation & Inflammation. Research subject areas Biomedical and life sciences Immunology Contact details leonie.taams@kcl.ac.uk
Methotrexate and ciclosporin both reduce levels of circulating IL-4 and IL-13 expressing CD4+ memory T-cells in childhood atopic dermatitis A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain? Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8 + T Cell Clones Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain Reply to Zhang and Jiao Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons Modelling inflammation-induced peripheral sensitization in a dish-more complex than expected? Reply to Zhao et al Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells A randomised controlled trial of the effect of intra-articular lidocaine on pain scores in inflammatory arthritis Substantive Similarities Between Synovial Fluid and Synovial Tissue T cells in Inflammatory Arthritis Via Single-Cell RNA and T cell Receptor Sequencing Erratum: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses (Nature Communications, (2023), 14, 1, (8487), 10.1038/s41467-023-42320-4) BiTE therapy for rheumatoid arthritis Clinical and Experimental Immunology: Highlights of 2023 Comparative analysis of centrally mediated and inflammatory pain experiences amongst patients diagnosed with rheumatoid arthritis: A multimethods study Lipidome profiling of neutrophil-derived extracellular vesicles unveils their contribution to the ensemble of synovial fluid-derived extracellular vesicles during joint inflammation Clinical and Experimental Immunology: highlights from 2022 Type 17-specific immune pathways are active in early spondyloarthritis Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: The protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis Psoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets Human in vitro-induced IL-17A+ CD8+ T-cells exert proinflammatory effects on synovial fibroblasts Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): A multicentre parallel group assessor-blinded clinical trial An interdisciplinary perspective on peripheral drivers of pain in rheumatoid arthritis Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses A systematic review and meta-analysis of questionnaires to screen for pain sensitisation and neuropathic like pain in inflammatory arthritis Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses Isolation and Functional Characterization of Regulatory CD4+ T Cells from the Inflamed Joints of Patients with Rheumatoid Arthritis Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma Clinical & Experimental Immunology: Highlights of 2021 Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19 Research priorities for neuroimmunology: Identifying the key research questions to be addressed by 2030 miR-155 overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T cell activation 55 years in the life of Clinical & Experimental Immunology Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation Drivers of Inflammation in Psoriatic Arthritis: the Old and the New Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Clinical & Experimental Immunology: Highlights of 2020 Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α activated fibroblast-like synoviocytes: an in vitro, co-culture model of inflammatory pain Immune checkpoint inhibition: from molecules to clinical application IKZF3/AIOLOs is associated with but not +sufficient T cells for the expression of IL-10 by CD4: IKZF3 is associated with IL-10+ CD4+ T cells Interleukin-17 in rheumatoid arthritis: Trials and tribulations Mechanisms of checkpoint inhibition induced adverse events Presence, function and regulation of IL-17F-expressing human CD4+ T cells Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype Polyfunctional, Proinflammatory, Tissue-Resident Memory Phenotype and Function of Synovial Interleukin-17A+CD8+ T Cells in Psoriatic Arthritis Neuroimmune interactions: how the nervous and immune systems influence each other Precision medicine in psoriatic arthritis: How should we select targeted therapies? The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127low Treg Cells in Patients with Chronic Rheumatoid Arthritis Delivery of miR-146a to Ly6Chigh monocytes inhibits pathogenic bone erosion in inflammatory arthritis View all publications
8 October 2025 King's and the Foundation for Liver Research appoint to the King's College Roger Williams Fellowship in Hepatology Dr Thomas Marjot DPhil, MRCP will hold the King’s College Roger Williams Fellowship in Hepatology…