
Professor Luigi Nibali
Head of the Centre for Host-Microbiome Interactions
- Professor of Periodontology
- Academic Lead and Director of the Postgraduate Periodontology Program
Research interests
- Dentistry
Contact details
Biography
Professor Luigi Nibali trained in dentistry at the University of Catania, Italy and completed his MSc and PhD in Periodontology at the UCL Eastman Dental Institute (EDI). His PhD topic was ‘Genetics of aggressive periodontitis’. From 2016, he worked part-time at the Centre for Immunobiology & Regenerative Medicine at the Queen Mary University (QMUL) as a Senior Lecturer and then Reader, continuing in private practice limited to periodontology and implant dentistry. He has been on the UK GDC Specialist list for Periodontics since 2007.
Luigi has published widely in periodontal and medical journals and received several periodontal research prizes, including the Fish Prize from the British Society of Periodontology and the Socransky Award from the International Association for Dental Research (IADR). He is on the Editorial Board of the Journal of Dental Research and the Journal of Clinical Periodontology. He is also the author of two books on periodontology and dysbiosis. His clinical focus his mainly on treating complex periodontal cases, particularly deep intrabony defects and molars with furcation involvement. His main research interests are minimally-invasive periodontal treatment, genetics/microbial risk factors for periodontitis and periodontal medicine. Together with his research team, he has proposed the concepts of periodontal infectogenomics and genetic dysbiosis, as part of an attempt to gain better understanding of the relationships between microbial triggers and host response in periodontitis.
He joined King's College London in June 2019 as Academic Lead and Director of the Postgraduate Periodontology program. In 2023 he was appointed Head of the Centre for Host-Microbiome Interactions.
Differential Response to Non-Surgical Periodontal Therapy Between Intrabony and Suprabony Defects: A Retrospective Analysis
Cuozzo, A., Arora, M., Marini, L., Hurley, J., Malaki, Z., Kang, J., Ramaglia, L. & Nibali, L., 19 May 2025, (E-pub ahead of print) In: Journal of Clinical Periodontology.Research output: Contribution to journal › Article › peer-review
Genetic Biomarkers for Periodontal Diseases: A Systematic Review
Dommisch, H., Hoedke, D., Lu, E.M.-C., Schafer, A., Richter, G., Kang, J. & Nibali, L., 8 Apr 2025, (E-pub ahead of print) In: Journal of Clinical Periodontology. 29 p., CPE-12-24-13140.R1.Research output: Contribution to journal › Article › peer-review
Genetic Biomarkers for Periodontal Diseases: A Systematic Review
Dommisch, H., Hoedke, D., Lu, E.M.-C., Schäfer, A., Richter, G., Kang, J. & Nibali, L., 8 Apr 2025, (E-pub ahead of print) In: Journal of Clinical Periodontology.Research output: Contribution to journal › Review article › peer-review
The application of a Fasting-mimicking Diet in Periodontitis. A feasibility study
Mainas, G., Ozgu, I., Sari, A., Vinciguerra, M., Ide, M., Bayraktar Ayakta, B., Ustun, K. & Nibali, L., May 2025, In: Journal of Dentistry. 156, 20 p., 105644.Research output: Contribution to journal › Article › peer-review
Association between calcium-channel blockers and gingival enlargement: A case-control study
Mainas, G., Santamaria, P., Zoheir, N., Alamri, M., Hughes, F., Lu, E.M.-C. & Nibali, L., Oct 2024, In: Journal of Dentistry. 149, 105315.Research output: Contribution to journal › Article › peer-review
Autologous Platelet Concentrates as Adjuncts to Non-Surgical Periodontal Therapy: A Systematic Review and Meta-Analysis
Lipovec , T., Kapadia , N., Antonoglou, G. N., Lu, E. M. C., Fawzy El-Sayed , K. M. & Nibali, L., 21 Dec 2024, (Accepted/In press) In: CLINICAL ORAL INVESTIGATIONS.Research output: Contribution to journal › Article › peer-review
Insights into microorganisms, associated factors, and the oral microbiome in infective endocarditis patients
Ismail, A., Yogarajah, A., Falconer, J. L., Dworakowski, R., Watson, S., Breeze, J., Gunning, M., Khan, H., Hussain, A., Howard, J. P., Cheong, P., Shah, M., Nibali, L. & Sousa, V., 2024, In: Frontiers in Oral health. 5, 1270492.Research output: Contribution to journal › Article › peer-review
Microbiological and molecular profile of furcation defects in a population with untreated periodontitis
Santamaria, P., Jin, Y., Ghuman, M., Shoaie, S., Spratt, D., Troiano, G. & Nibali, L., Nov 2024, In: Journal of Clinical Periodontology. 51, 11, p. 1421-1432 12 p.Research output: Contribution to journal › Article › peer-review
MINIMALLY-INVASIVE NON-SURGICAL PERIODONTAL THERAPY OF INTRABONY DEFECTS: A PROSPECTIVE MULTICENTRE COHORT STUDY
Mehta, J., Montevecchi, M., Garcia-Sanchez, R., Onabolu, O., Linares, A., Eriksson, F., Ghezzi, C., Donghi, C., Lu, E. M. C. & Nibali, L., 6 May 2024, In: Journal of Clinical Periodontology. 51, 7, p. 905-914 doi: 10.1111/jcpe.13984.Research output: Contribution to journal › Article › peer-review
Periodontal granulation tissue – To remove or not to remove, that is the question
Sam, Y. H., Nibali, L. & Ghuman, M., Aug 2024, In: Journal of Periodontal Research. 59, 4, p. 636-646 11 p.Research output: Contribution to journal › Review article › peer-review
Prevalence and severity of periodontal disease in the host community and Rohingya refugees living in camps in Bangladesh
Zaheer, K., Jonayed Hossain, M., Isha, I., Delgado Angulo, E. & Nibali, L., Dec 2024, In: Community Dentistry and Oral Epidemiology. 52, 6, p. 817-823 7 p.Research output: Contribution to journal › Article › peer-review
The promise and challenges of genomics-informed periodontal disease diagnoses
Nibali, L., Divaris, K. & Lu, E. M. C., 28 Jul 2024, In: Journal of Clinical Periodontology. 95, 1, p. 194-202 9 p.Research output: Contribution to journal › Review article › peer-review
Could dietary restrictions affect periodontal disease? A systematic review
Mainas, G., Santamaria, P., Ide, M., Longo, V., Vinciguerra, M., Nart, J. & Nibali, L., Aug 2023, In: CLINICAL ORAL INVESTIGATIONS. 27, 8, p. 4107-4116 10 p.Research output: Contribution to journal › Article › peer-review
Host Genotype Links to Salivary and Gut Microbiota by Periodontal Status
Kurushima, Y., Wells, P. M., Bowyer, R. C. E., Zoheir, N., Doran, S., Richardson, J. P., Sprockett, D. D., Relman, D. A., Steves, C. J. & Nibali, L., 1 Feb 2023, In: Journal of Dental Research. 102, 2, p. 146-156Research output: Contribution to journal › Article › peer-review
Metabolomics Analysis in Saliva from Periodontally Healthy, Gingivitis and Periodontitis Patients
Alamri, M., Williams, B., Le Guennec, A., Mainas, G., Nibali, L. & Moyes, D., 5 Sept 2023, (Accepted/In press) In: Journal of Periodontal Research.Research output: Contribution to journal › Article › peer-review
Minimal invasiveness in nonsurgical periodontal therapy
Nibali, L., Feb 2023, In: PERIODONTOLOGY 2000. 91, 1, p. 7-19 13 p.Research output: Contribution to journal › Review article › peer-review
Repurposing Metformin for periodontal disease management as a form of oral-systemic preventive medicine
Neves, V., Okajima, L. S., Elbahtety, E., Joseph, S., Daly, J., Menon, A., Fan, D., Volkyte, A., Mainas, G., Fung, K., Dhami, R., Pelegrine, A. A., Sharpe, P., Nibali, L. & Ide, M., 10 Oct 2023, In: Journal Of Translational Medicine. 21, 1, 18 p., 655.Research output: Contribution to journal › Article › peer-review
The efficacy of bone reconstructive therapies in the management of peri-implantitis. A systematic review and meta-analysis
Donos, N., Calciolari, E., Ghuman, M., Baccini, M., Sousa, V. & Nibali, L., Jun 2023, In: Journal of Clinical Periodontology. 50, S26, p. 285-316 32 p.Research output: Contribution to journal › Review article › peer-review
Adjunctive effect of systemic antibiotics in regenerative/reconstructive periodontal surgery— a systematic review with meta-analysis
Nibali, L., Buti, J., Barbato, L., Cairo, F., Graziani, F. & Jepsen, S., Jan 2022, In: Antibiotics. 11, 1, 8.Research output: Contribution to journal › Article › peer-review
Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome
Nibali, L., Stephen, A., Hagi-Pavli, E., Allaker, R., Pino, A. D., Terranova, V., Pisano, M., Marca, S. D., Ferrara, V., Scicali, R., Giordano, M., Purrello, F., Donos, N. & Malatino, L., Mar 2022, In: Journal of Dentistry. 118, 104065.Research output: Contribution to journal › Article › peer-review
A New Comorbidity in Periodontitis: Fusobacterium nucleatum and Colorectal Cancer
Mesa, F., Mesa-Lopez, M. J., Egea-Valenzuela, J., Benavides-Reyes, C., Nibali, L., Ide, M., Mainas, G., Rizzo, M. & Magan-Fernandex, A., 15 Apr 2022, In: Medicina. 58, 4, p. 546 546.Research output: Contribution to journal › Review article › peer-review
Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence
Mainas, G., Nibali, L., Ide, M., Al Mahmeed, W., Al-Rasadi, K., Al-Alawi, K., Banach, M., Banerjee, Y., Ceriello, A., Cesur, M. & Rizzo, M., 26 Dec 2022, In: Metabolites. 23, p. 40 17 p., 13010040.Research output: Contribution to journal › Review article › peer-review
Comparison of the efficacy of periodontal prognostic systems in predicting tooth loss
Saydzai, S., Buontempo, Z., Patel, P., Hasan, F., Sun, C., Akcalı, A., Lin, G. H., Donos, N. & Nibali, L., Aug 2022, In: Journal of Clinical Periodontology. 49, 8, p. 740-748 9 p.Research output: Contribution to journal › Article › peer-review
Evaluating Clinical Utility of Subgingival and Salivary Endotoxin Activity Levels as Periodontal Biomarkers
Zaric, S., Strachan, A., Kurushima, Y., Dong, B., Mcilwaine, C., Harrington, Z., Nibali, L., Foey, A. & Ide, M., 1 Nov 2022, In: Frontiers in Oral health. 9 p., 1029806.Research output: Contribution to journal › Article › peer-review
Evaluation of IL-23p19/Ebi3 (IL-39) gingival crevicular fluid levels in periodontal health, gingivitis, and periodontitis
Sari, A., Dogan, S., Nibali, L. & Koseoglu, S., Dec 2022, In: CLINICAL ORAL INVESTIGATIONS. 26, 12, p. 7209-7218 10 p.Research output: Contribution to journal › Article › peer-review
Expression of periodontitis susceptibility genes in human gingiva using single-cell RNA sequencing
Caetano, A. J., D'Agostino, E. M., Sharpe, P. & Nibali, L., Dec 2022, In: Journal of Periodontal Research. 57, 6, p. 1210-1218 9 p.Research output: Contribution to journal › Article › peer-review
Implementation of a software application in staging and grading of periodontitis cases
Marini, L., Tonetti, M. S., Nibali, L., Sforza, N. M., Landi, L., Cavalcanti, R., Rojas, M. A. & Pilloni, A., 2022, (Accepted/In press) In: Oral Diseases.Research output: Contribution to journal › Article › peer-review
Managing the systemic impact of Periodontitis
Mainas, G., Ide, M., Rizzo, M., Magan-Fernandex, A., Mesa, F. & Nibali, L., 29 Apr 2022, In: Medicina. 58, 5, 621.Research output: Contribution to journal › Review article › peer-review
Molecular Mechanisms Leading from Periodontal Disease to Cancer
Sobocki, B. K., Basset, C. A., Bruhn-Olszewska, B., Olszewski, P., Szot, O., Kaźmierczak-Siedlecka, K., Guziak, M., Nibali, L. & Leone, A., 1 Jan 2022, In: International Journal of Molecular Sciences. 23, 2, 970.Research output: Contribution to journal › Article › peer-review
New Insights into the Pathogenesis of Periodontal Diseases
Zaric, S., Ide, M. & Nibali, L., 19 Apr 2022, In: Dental Update. 49, 4, p. 314-317 4 p.Research output: Contribution to journal › Review article › peer-review
Patterns of subgingival microbiota in different periodontal phenotypes
Nibali, L., Sousa, V., Davrandi, M., Liu, L. S., Spratt, D. & Donos, N., Feb 2022, In: Journal of Dentistry. 117, 103912.Research output: Contribution to journal › Article › peer-review
Periodontal infectogenomics: a systematic review update of associations between host genetic variants and subgingival microbial detection
Zoheir, N., Kurushima, Y., Lin, G. H. & Nibali, L., Mar 2022, In: CLINICAL ORAL INVESTIGATIONS. 26, 3, p. 2209-2221 13 p.Research output: Contribution to journal › Review article › peer-review
Periodontitis and implant complications in diabetes
Nibali, L., Gkranias, N., Mainas, G. & Di Pino, A., Oct 2022, In: PERIODONTOLOGY 2000. 90, 1, p. 88-105 18 p.Research output: Contribution to journal › Review article › peer-review
Retrospective exploratory study of smoking status and e-cigarette use with response to non-surgical periodontal therapy
Shah, C., Holtfreter, B., Hughes, F. J. & Nibali, L., 2022, (Accepted/In press) In: Journal of Periodontology.Research output: Contribution to journal › Article › peer-review
Guest Editorial: Time to reflect on new evidence about periodontal regenerative surgery of intrabony defects
Nibali, L., Apr 2021, In: Journal of Clinical Periodontology. 48, 4, p. 557-559 3 p.Research output: Contribution to journal › Editorial › peer-review
Microbiome differences in periodontal, peri-implant, and healthy sites: a cross-sectional pilot study
Barbagallo, G., Santagati, M., Guni, A., Torrisi, P., Spitale, A., Stefani, S., Ferlito, S. & Nibali, L., 26 Nov 2021, (E-pub ahead of print) In: CLINICAL ORAL INVESTIGATIONS.Research output: Contribution to journal › Article › peer-review
Molecular profiling of intrabony defects' gingival crevicular fluid
Koidou, V. P., Hagi-Pavli, E., Cross, S., Nibali, L. & Donos, N., 17 Nov 2021, (E-pub ahead of print) In: Journal of Periodontal Research. 57, 1, 10 p.Research output: Contribution to journal › Article › peer-review
Patients’ and dentists’ perceptions of Tele-Dentistry at the time of COVID-19. A questionnaire-based study: Tele-dentistry at the time of COVID-19
Menhadji, P., Patel, R., Asimakopoulou, K., Quinn, B., Khoshkhounejad, G., Heidarzadeh Pasha, P., Ide, M., Garcia Sanchez, R., Kalsi, P. & Nibali, L., Oct 2021, In: Journal of Dentistry. 113, 103782.Research output: Contribution to journal › Article › peer-review
Periodontal furcation lesions: A survey of diagnosis and management by general dental practitioners
Nibali, L., Shemie, M., Li, G., Ting, R., Asimakopoulou, K., Barbagallo, G., Lee, R., Eickholz, P., Kocher, T., Walter, C., Aimetti, M. & Rüdiger, S., Nov 2021, In: Journal of Clinical Periodontology. 48, 11, p. 1441-1448 8 p.Research output: Contribution to journal › Article › peer-review
Periodontal health and disease: The contribution of genetics
Shaddox, L. M., Morford, L. A. & Nibali, L., Feb 2021, In: PERIODONTOLOGY 2000. 85, 1, p. 161-181 21 p.Research output: Contribution to journal › Review article › peer-review
Periodontal infrabony defects: Systematic review of healing by defect morphology following regenerative surgery
Nibali, L., Sultan, D., Arena, C., Pelekos, G., Lin, G. H. & Tonetti, M., Jan 2021, In: Journal of Clinical Periodontology. 48, 1, p. 100-113 14 p.Research output: Contribution to journal › Review article › peer-review
Periodontal status in children with primary immunodeficiencies
Nibali, L., Bayliss-Chapman, J., Halai, H., Somani, C., Davies, J., Ancliff, P. & Donos, N., Aug 2021, In: Journal of Periodontal Research. 56, 4, p. 819-827 9 p.Research output: Contribution to journal › Article › peer-review
Study design and primary outcome in randomized controlled trials in periodontology. A systematic review
Alshamsi, M., Mehta, J. & Nibali, L., Jun 2021, In: Journal of Clinical Periodontology. 48, 6, p. 859-866 8 p.Research output: Contribution to journal › Review article › peer-review
Subgingival periodontal pathogens in Down syndrome children without periodontal breakdown. A case-control study on deciduous teeth
Vocale, C., Montevecchi, M., D’Alessandro, G., Gatto, M., Piana, G., Nibali, L., Re, M. C. & Sambri, V., Dec 2021, In: EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY. 22, 4, p. 309-313 5 p.Research output: Contribution to journal › Article › peer-review
The effect of plaque control in the treatment of Oral Lichen Planus with gingival manifestations: a Systematic Review
Albaghli, F., Zhou, Y., Hsu, C. C. & Nibali, L., Jun 2021, In: Community Dental Health. 38, 2, p. 112-118 7 p.Research output: Contribution to journal › Article › peer-review
Tooth loss and radiographic bone loss in patients without regular supportive care: A retrospective study
Al-Harthi, S., Barbagallo, G., Psaila, A., d'Urso, U. & Nibali, L., Nov 2021, (E-pub ahead of print) In: Journal of Periodontology. 93, 3Research output: Contribution to journal › Article › peer-review
Accuracy of single molecular biomarkers in saliva for the diagnosis of periodontitis: A systematic review and meta-analysis
Arias-Bujanda, N., Regueira-Iglesias, A., Balsa-Castro, C., Nibali, L., Donos, N. & Tomás, I., 1 Jan 2020, In: Journal of Clinical Periodontology. 47, 1, p. 2-18 17 p.Research output: Contribution to journal › Review article › peer-review
Association of oral health-related quality of life measures with aggressive and chronic periodontitis
Fuller, J., Donos, N., Suvan, J., Tsakos, G. & Nibali, L., 1 Aug 2020, In: Journal of Periodontal Research. 55, 4, p. 574-580 7 p.Research output: Contribution to journal › Article › peer-review
Differences in the periodontal microbiome of successfully treated and persistent aggressive periodontitis
Nibali, L., Sousa, V., Davrandi, M., Spratt, D., Alyahya, Q., Dopico, J. & Donos, N., 1 Aug 2020, In: Journal of Clinical Periodontology. 47, 8, p. 980-990 11 p.Research output: Contribution to journal › Article › peer-review
Effect of nonsurgical periodontal therapy on haematological parameters in grades B and C periodontitis: an exploratory analysis
Eickholz, P., Schröder, M., Asendorf, A., Schacher, B., Oremek, G. M., Kaiser, F., Wohlfeil, M. & Nibali, L., Dec 2020, In: CLINICAL ORAL INVESTIGATIONS. 24, 12, p. 4291-4299 9 p.Research output: Contribution to journal › Article › peer-review
Research

Periodontology and Periodontal Medicine
Research into periodontal and peri-implant diseases with the aim to improve patient care and quality of life.

Centre for Host-Microbiome Interactions
Millions of microorganisms live in and on our bodies forming microbiomes on different surfaces. Researchers in the Centre for Host Microbiome Interactions study our relationship with these bacteria and fungi in health or in oral and systemic diseases such as periodontitis, candidiasis, oral cancer and Alzheimer’s disease.
News
SMART design shows feasibility for clinical trials when treating challenging periodontal cases
Researchers from the Faculty of Dentistry, Oral & Craniofacial Sciences at King’s College London have conducted the first randomised controlled trial for the...

Faculty of Dentistry, Oral & Craniofacial Sciences 2025 Staff Awards
Colleagues from FoDOCS came together at the start of April to celebrate the remarkable, diverse and hugely impactful contributions that individuals and teams...

A Fasting-mimicking diet may reduce inflammation in patients with severe periodontal disease
In a feasibility study by King’s College London researchers, a team explored the potential benefits of incorporating a fasting-mimicking diet together with...

King's College London study finds minimally-invasive non-surgical treatment has positive outcomes in treating intrabony defects
In a new study published in the Journal of Clinical Periodontology, the team from the Faculty of Dentistry, Oral & Craniofacial Sciences at King’s College...

Dietary restrictions could reduce gum disease
New research from King’s College London has emerged that shows calorie restriction (500-1300 calories per day) could be used to reduce gum disease.

Tele-dentistry a viable option for replacing in-person initial consultations, new study finds
A study led by a team of periodontists and psychologists at King’s College London including dentistry consultants at Guy’s Hospital has found that...

Children with immune deficiencies more likely to have gum disease, study finds
Researchers at King’s College London have found that children with Primary Immunodeficiencies have higher prevalence of periodontal (gum) disease.

Exploring the COVID 19 impact on delivering periodontology treatments
Academics and undergraduate students at King’s investigate how COVID-19 has impacted periodontal practice in the UK.

Differential Response to Non-Surgical Periodontal Therapy Between Intrabony and Suprabony Defects: A Retrospective Analysis
Cuozzo, A., Arora, M., Marini, L., Hurley, J., Malaki, Z., Kang, J., Ramaglia, L. & Nibali, L., 19 May 2025, (E-pub ahead of print) In: Journal of Clinical Periodontology.Research output: Contribution to journal › Article › peer-review
Genetic Biomarkers for Periodontal Diseases: A Systematic Review
Dommisch, H., Hoedke, D., Lu, E.M.-C., Schafer, A., Richter, G., Kang, J. & Nibali, L., 8 Apr 2025, (E-pub ahead of print) In: Journal of Clinical Periodontology. 29 p., CPE-12-24-13140.R1.Research output: Contribution to journal › Article › peer-review
Genetic Biomarkers for Periodontal Diseases: A Systematic Review
Dommisch, H., Hoedke, D., Lu, E.M.-C., Schäfer, A., Richter, G., Kang, J. & Nibali, L., 8 Apr 2025, (E-pub ahead of print) In: Journal of Clinical Periodontology.Research output: Contribution to journal › Review article › peer-review
The application of a Fasting-mimicking Diet in Periodontitis. A feasibility study
Mainas, G., Ozgu, I., Sari, A., Vinciguerra, M., Ide, M., Bayraktar Ayakta, B., Ustun, K. & Nibali, L., May 2025, In: Journal of Dentistry. 156, 20 p., 105644.Research output: Contribution to journal › Article › peer-review
Association between calcium-channel blockers and gingival enlargement: A case-control study
Mainas, G., Santamaria, P., Zoheir, N., Alamri, M., Hughes, F., Lu, E.M.-C. & Nibali, L., Oct 2024, In: Journal of Dentistry. 149, 105315.Research output: Contribution to journal › Article › peer-review
Autologous Platelet Concentrates as Adjuncts to Non-Surgical Periodontal Therapy: A Systematic Review and Meta-Analysis
Lipovec , T., Kapadia , N., Antonoglou, G. N., Lu, E. M. C., Fawzy El-Sayed , K. M. & Nibali, L., 21 Dec 2024, (Accepted/In press) In: CLINICAL ORAL INVESTIGATIONS.Research output: Contribution to journal › Article › peer-review
Insights into microorganisms, associated factors, and the oral microbiome in infective endocarditis patients
Ismail, A., Yogarajah, A., Falconer, J. L., Dworakowski, R., Watson, S., Breeze, J., Gunning, M., Khan, H., Hussain, A., Howard, J. P., Cheong, P., Shah, M., Nibali, L. & Sousa, V., 2024, In: Frontiers in Oral health. 5, 1270492.Research output: Contribution to journal › Article › peer-review
Microbiological and molecular profile of furcation defects in a population with untreated periodontitis
Santamaria, P., Jin, Y., Ghuman, M., Shoaie, S., Spratt, D., Troiano, G. & Nibali, L., Nov 2024, In: Journal of Clinical Periodontology. 51, 11, p. 1421-1432 12 p.Research output: Contribution to journal › Article › peer-review
MINIMALLY-INVASIVE NON-SURGICAL PERIODONTAL THERAPY OF INTRABONY DEFECTS: A PROSPECTIVE MULTICENTRE COHORT STUDY
Mehta, J., Montevecchi, M., Garcia-Sanchez, R., Onabolu, O., Linares, A., Eriksson, F., Ghezzi, C., Donghi, C., Lu, E. M. C. & Nibali, L., 6 May 2024, In: Journal of Clinical Periodontology. 51, 7, p. 905-914 doi: 10.1111/jcpe.13984.Research output: Contribution to journal › Article › peer-review
Periodontal granulation tissue – To remove or not to remove, that is the question
Sam, Y. H., Nibali, L. & Ghuman, M., Aug 2024, In: Journal of Periodontal Research. 59, 4, p. 636-646 11 p.Research output: Contribution to journal › Review article › peer-review
Prevalence and severity of periodontal disease in the host community and Rohingya refugees living in camps in Bangladesh
Zaheer, K., Jonayed Hossain, M., Isha, I., Delgado Angulo, E. & Nibali, L., Dec 2024, In: Community Dentistry and Oral Epidemiology. 52, 6, p. 817-823 7 p.Research output: Contribution to journal › Article › peer-review
The promise and challenges of genomics-informed periodontal disease diagnoses
Nibali, L., Divaris, K. & Lu, E. M. C., 28 Jul 2024, In: Journal of Clinical Periodontology. 95, 1, p. 194-202 9 p.Research output: Contribution to journal › Review article › peer-review
Could dietary restrictions affect periodontal disease? A systematic review
Mainas, G., Santamaria, P., Ide, M., Longo, V., Vinciguerra, M., Nart, J. & Nibali, L., Aug 2023, In: CLINICAL ORAL INVESTIGATIONS. 27, 8, p. 4107-4116 10 p.Research output: Contribution to journal › Article › peer-review
Host Genotype Links to Salivary and Gut Microbiota by Periodontal Status
Kurushima, Y., Wells, P. M., Bowyer, R. C. E., Zoheir, N., Doran, S., Richardson, J. P., Sprockett, D. D., Relman, D. A., Steves, C. J. & Nibali, L., 1 Feb 2023, In: Journal of Dental Research. 102, 2, p. 146-156Research output: Contribution to journal › Article › peer-review
Metabolomics Analysis in Saliva from Periodontally Healthy, Gingivitis and Periodontitis Patients
Alamri, M., Williams, B., Le Guennec, A., Mainas, G., Nibali, L. & Moyes, D., 5 Sept 2023, (Accepted/In press) In: Journal of Periodontal Research.Research output: Contribution to journal › Article › peer-review
Minimal invasiveness in nonsurgical periodontal therapy
Nibali, L., Feb 2023, In: PERIODONTOLOGY 2000. 91, 1, p. 7-19 13 p.Research output: Contribution to journal › Review article › peer-review
Repurposing Metformin for periodontal disease management as a form of oral-systemic preventive medicine
Neves, V., Okajima, L. S., Elbahtety, E., Joseph, S., Daly, J., Menon, A., Fan, D., Volkyte, A., Mainas, G., Fung, K., Dhami, R., Pelegrine, A. A., Sharpe, P., Nibali, L. & Ide, M., 10 Oct 2023, In: Journal Of Translational Medicine. 21, 1, 18 p., 655.Research output: Contribution to journal › Article › peer-review
The efficacy of bone reconstructive therapies in the management of peri-implantitis. A systematic review and meta-analysis
Donos, N., Calciolari, E., Ghuman, M., Baccini, M., Sousa, V. & Nibali, L., Jun 2023, In: Journal of Clinical Periodontology. 50, S26, p. 285-316 32 p.Research output: Contribution to journal › Review article › peer-review
Adjunctive effect of systemic antibiotics in regenerative/reconstructive periodontal surgery— a systematic review with meta-analysis
Nibali, L., Buti, J., Barbato, L., Cairo, F., Graziani, F. & Jepsen, S., Jan 2022, In: Antibiotics. 11, 1, 8.Research output: Contribution to journal › Article › peer-review
Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome
Nibali, L., Stephen, A., Hagi-Pavli, E., Allaker, R., Pino, A. D., Terranova, V., Pisano, M., Marca, S. D., Ferrara, V., Scicali, R., Giordano, M., Purrello, F., Donos, N. & Malatino, L., Mar 2022, In: Journal of Dentistry. 118, 104065.Research output: Contribution to journal › Article › peer-review
A New Comorbidity in Periodontitis: Fusobacterium nucleatum and Colorectal Cancer
Mesa, F., Mesa-Lopez, M. J., Egea-Valenzuela, J., Benavides-Reyes, C., Nibali, L., Ide, M., Mainas, G., Rizzo, M. & Magan-Fernandex, A., 15 Apr 2022, In: Medicina. 58, 4, p. 546 546.Research output: Contribution to journal › Review article › peer-review
Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence
Mainas, G., Nibali, L., Ide, M., Al Mahmeed, W., Al-Rasadi, K., Al-Alawi, K., Banach, M., Banerjee, Y., Ceriello, A., Cesur, M. & Rizzo, M., 26 Dec 2022, In: Metabolites. 23, p. 40 17 p., 13010040.Research output: Contribution to journal › Review article › peer-review
Comparison of the efficacy of periodontal prognostic systems in predicting tooth loss
Saydzai, S., Buontempo, Z., Patel, P., Hasan, F., Sun, C., Akcalı, A., Lin, G. H., Donos, N. & Nibali, L., Aug 2022, In: Journal of Clinical Periodontology. 49, 8, p. 740-748 9 p.Research output: Contribution to journal › Article › peer-review
Evaluating Clinical Utility of Subgingival and Salivary Endotoxin Activity Levels as Periodontal Biomarkers
Zaric, S., Strachan, A., Kurushima, Y., Dong, B., Mcilwaine, C., Harrington, Z., Nibali, L., Foey, A. & Ide, M., 1 Nov 2022, In: Frontiers in Oral health. 9 p., 1029806.Research output: Contribution to journal › Article › peer-review
Evaluation of IL-23p19/Ebi3 (IL-39) gingival crevicular fluid levels in periodontal health, gingivitis, and periodontitis
Sari, A., Dogan, S., Nibali, L. & Koseoglu, S., Dec 2022, In: CLINICAL ORAL INVESTIGATIONS. 26, 12, p. 7209-7218 10 p.Research output: Contribution to journal › Article › peer-review
Expression of periodontitis susceptibility genes in human gingiva using single-cell RNA sequencing
Caetano, A. J., D'Agostino, E. M., Sharpe, P. & Nibali, L., Dec 2022, In: Journal of Periodontal Research. 57, 6, p. 1210-1218 9 p.Research output: Contribution to journal › Article › peer-review
Implementation of a software application in staging and grading of periodontitis cases
Marini, L., Tonetti, M. S., Nibali, L., Sforza, N. M., Landi, L., Cavalcanti, R., Rojas, M. A. & Pilloni, A., 2022, (Accepted/In press) In: Oral Diseases.Research output: Contribution to journal › Article › peer-review
Managing the systemic impact of Periodontitis
Mainas, G., Ide, M., Rizzo, M., Magan-Fernandex, A., Mesa, F. & Nibali, L., 29 Apr 2022, In: Medicina. 58, 5, 621.Research output: Contribution to journal › Review article › peer-review
Molecular Mechanisms Leading from Periodontal Disease to Cancer
Sobocki, B. K., Basset, C. A., Bruhn-Olszewska, B., Olszewski, P., Szot, O., Kaźmierczak-Siedlecka, K., Guziak, M., Nibali, L. & Leone, A., 1 Jan 2022, In: International Journal of Molecular Sciences. 23, 2, 970.Research output: Contribution to journal › Article › peer-review
New Insights into the Pathogenesis of Periodontal Diseases
Zaric, S., Ide, M. & Nibali, L., 19 Apr 2022, In: Dental Update. 49, 4, p. 314-317 4 p.Research output: Contribution to journal › Review article › peer-review
Patterns of subgingival microbiota in different periodontal phenotypes
Nibali, L., Sousa, V., Davrandi, M., Liu, L. S., Spratt, D. & Donos, N., Feb 2022, In: Journal of Dentistry. 117, 103912.Research output: Contribution to journal › Article › peer-review
Periodontal infectogenomics: a systematic review update of associations between host genetic variants and subgingival microbial detection
Zoheir, N., Kurushima, Y., Lin, G. H. & Nibali, L., Mar 2022, In: CLINICAL ORAL INVESTIGATIONS. 26, 3, p. 2209-2221 13 p.Research output: Contribution to journal › Review article › peer-review
Periodontitis and implant complications in diabetes
Nibali, L., Gkranias, N., Mainas, G. & Di Pino, A., Oct 2022, In: PERIODONTOLOGY 2000. 90, 1, p. 88-105 18 p.Research output: Contribution to journal › Review article › peer-review
Retrospective exploratory study of smoking status and e-cigarette use with response to non-surgical periodontal therapy
Shah, C., Holtfreter, B., Hughes, F. J. & Nibali, L., 2022, (Accepted/In press) In: Journal of Periodontology.Research output: Contribution to journal › Article › peer-review
Guest Editorial: Time to reflect on new evidence about periodontal regenerative surgery of intrabony defects
Nibali, L., Apr 2021, In: Journal of Clinical Periodontology. 48, 4, p. 557-559 3 p.Research output: Contribution to journal › Editorial › peer-review
Microbiome differences in periodontal, peri-implant, and healthy sites: a cross-sectional pilot study
Barbagallo, G., Santagati, M., Guni, A., Torrisi, P., Spitale, A., Stefani, S., Ferlito, S. & Nibali, L., 26 Nov 2021, (E-pub ahead of print) In: CLINICAL ORAL INVESTIGATIONS.Research output: Contribution to journal › Article › peer-review
Molecular profiling of intrabony defects' gingival crevicular fluid
Koidou, V. P., Hagi-Pavli, E., Cross, S., Nibali, L. & Donos, N., 17 Nov 2021, (E-pub ahead of print) In: Journal of Periodontal Research. 57, 1, 10 p.Research output: Contribution to journal › Article › peer-review
Patients’ and dentists’ perceptions of Tele-Dentistry at the time of COVID-19. A questionnaire-based study: Tele-dentistry at the time of COVID-19
Menhadji, P., Patel, R., Asimakopoulou, K., Quinn, B., Khoshkhounejad, G., Heidarzadeh Pasha, P., Ide, M., Garcia Sanchez, R., Kalsi, P. & Nibali, L., Oct 2021, In: Journal of Dentistry. 113, 103782.Research output: Contribution to journal › Article › peer-review
Periodontal furcation lesions: A survey of diagnosis and management by general dental practitioners
Nibali, L., Shemie, M., Li, G., Ting, R., Asimakopoulou, K., Barbagallo, G., Lee, R., Eickholz, P., Kocher, T., Walter, C., Aimetti, M. & Rüdiger, S., Nov 2021, In: Journal of Clinical Periodontology. 48, 11, p. 1441-1448 8 p.Research output: Contribution to journal › Article › peer-review
Periodontal health and disease: The contribution of genetics
Shaddox, L. M., Morford, L. A. & Nibali, L., Feb 2021, In: PERIODONTOLOGY 2000. 85, 1, p. 161-181 21 p.Research output: Contribution to journal › Review article › peer-review
Periodontal infrabony defects: Systematic review of healing by defect morphology following regenerative surgery
Nibali, L., Sultan, D., Arena, C., Pelekos, G., Lin, G. H. & Tonetti, M., Jan 2021, In: Journal of Clinical Periodontology. 48, 1, p. 100-113 14 p.Research output: Contribution to journal › Review article › peer-review
Periodontal status in children with primary immunodeficiencies
Nibali, L., Bayliss-Chapman, J., Halai, H., Somani, C., Davies, J., Ancliff, P. & Donos, N., Aug 2021, In: Journal of Periodontal Research. 56, 4, p. 819-827 9 p.Research output: Contribution to journal › Article › peer-review
Study design and primary outcome in randomized controlled trials in periodontology. A systematic review
Alshamsi, M., Mehta, J. & Nibali, L., Jun 2021, In: Journal of Clinical Periodontology. 48, 6, p. 859-866 8 p.Research output: Contribution to journal › Review article › peer-review
Subgingival periodontal pathogens in Down syndrome children without periodontal breakdown. A case-control study on deciduous teeth
Vocale, C., Montevecchi, M., D’Alessandro, G., Gatto, M., Piana, G., Nibali, L., Re, M. C. & Sambri, V., Dec 2021, In: EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY. 22, 4, p. 309-313 5 p.Research output: Contribution to journal › Article › peer-review
The effect of plaque control in the treatment of Oral Lichen Planus with gingival manifestations: a Systematic Review
Albaghli, F., Zhou, Y., Hsu, C. C. & Nibali, L., Jun 2021, In: Community Dental Health. 38, 2, p. 112-118 7 p.Research output: Contribution to journal › Article › peer-review
Tooth loss and radiographic bone loss in patients without regular supportive care: A retrospective study
Al-Harthi, S., Barbagallo, G., Psaila, A., d'Urso, U. & Nibali, L., Nov 2021, (E-pub ahead of print) In: Journal of Periodontology. 93, 3Research output: Contribution to journal › Article › peer-review
Accuracy of single molecular biomarkers in saliva for the diagnosis of periodontitis: A systematic review and meta-analysis
Arias-Bujanda, N., Regueira-Iglesias, A., Balsa-Castro, C., Nibali, L., Donos, N. & Tomás, I., 1 Jan 2020, In: Journal of Clinical Periodontology. 47, 1, p. 2-18 17 p.Research output: Contribution to journal › Review article › peer-review
Association of oral health-related quality of life measures with aggressive and chronic periodontitis
Fuller, J., Donos, N., Suvan, J., Tsakos, G. & Nibali, L., 1 Aug 2020, In: Journal of Periodontal Research. 55, 4, p. 574-580 7 p.Research output: Contribution to journal › Article › peer-review
Differences in the periodontal microbiome of successfully treated and persistent aggressive periodontitis
Nibali, L., Sousa, V., Davrandi, M., Spratt, D., Alyahya, Q., Dopico, J. & Donos, N., 1 Aug 2020, In: Journal of Clinical Periodontology. 47, 8, p. 980-990 11 p.Research output: Contribution to journal › Article › peer-review
Effect of nonsurgical periodontal therapy on haematological parameters in grades B and C periodontitis: an exploratory analysis
Eickholz, P., Schröder, M., Asendorf, A., Schacher, B., Oremek, G. M., Kaiser, F., Wohlfeil, M. & Nibali, L., Dec 2020, In: CLINICAL ORAL INVESTIGATIONS. 24, 12, p. 4291-4299 9 p.Research output: Contribution to journal › Article › peer-review
Research

Periodontology and Periodontal Medicine
Research into periodontal and peri-implant diseases with the aim to improve patient care and quality of life.

Centre for Host-Microbiome Interactions
Millions of microorganisms live in and on our bodies forming microbiomes on different surfaces. Researchers in the Centre for Host Microbiome Interactions study our relationship with these bacteria and fungi in health or in oral and systemic diseases such as periodontitis, candidiasis, oral cancer and Alzheimer’s disease.
News
SMART design shows feasibility for clinical trials when treating challenging periodontal cases
Researchers from the Faculty of Dentistry, Oral & Craniofacial Sciences at King’s College London have conducted the first randomised controlled trial for the...

Faculty of Dentistry, Oral & Craniofacial Sciences 2025 Staff Awards
Colleagues from FoDOCS came together at the start of April to celebrate the remarkable, diverse and hugely impactful contributions that individuals and teams...

A Fasting-mimicking diet may reduce inflammation in patients with severe periodontal disease
In a feasibility study by King’s College London researchers, a team explored the potential benefits of incorporating a fasting-mimicking diet together with...

King's College London study finds minimally-invasive non-surgical treatment has positive outcomes in treating intrabony defects
In a new study published in the Journal of Clinical Periodontology, the team from the Faculty of Dentistry, Oral & Craniofacial Sciences at King’s College...

Dietary restrictions could reduce gum disease
New research from King’s College London has emerged that shows calorie restriction (500-1300 calories per day) could be used to reduce gum disease.

Tele-dentistry a viable option for replacing in-person initial consultations, new study finds
A study led by a team of periodontists and psychologists at King’s College London including dentistry consultants at Guy’s Hospital has found that...

Children with immune deficiencies more likely to have gum disease, study finds
Researchers at King’s College London have found that children with Primary Immunodeficiencies have higher prevalence of periodontal (gum) disease.

Exploring the COVID 19 impact on delivering periodontology treatments
Academics and undergraduate students at King’s investigate how COVID-19 has impacted periodontal practice in the UK.
