Professor Peter Parker Academics Supervisors Professor of Cancer Cell Biology and Director of the CRUK KHP Centre Research subject areas Cancer Contact details peter.parker@kcl.ac.uk +44 (0) 20 7848 6616
Editorial: Signaling by Small GTPases in Metastatic Disease Parker, P. J. & Kishore, U., 21 Jan 2022, In: Frontiers in Cell and Developmental Biology. 10, 841572. Research output: Contribution to journal › Editorial › peer-review. DOIs: https://doi.org/10.3389/fcell.2022.841572 A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division Martini, S., Davis, K., Faraway, R., Elze, L., Lockwood, N., Jones, A., Xie, X., McDonald, N. Q., Mann, D. J., Armstrong, A., Ule, J. & Parker, P. J., Dec 2021, In: Nature Communications. 12, 1, p. 6934 6934. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-021-27189-5 Immunogenomics of colorectal cancer response to checkpoint blockade: analysis of the KEYNOTE 177 trial and validation cohorts Bortolomeazzi, M., Keddar, M. R., Montorsi, L., Acha-sagredo, A., Benedetti, L., Temelkovski, D., Choi, S., Petrov, N., Todd, K., Wai, P., Kohl, J., Denner, T., Nye, E., Goldstone, R., Ward, S., Wilson, G. A., Al Bakir, M., Swanton, C., John, S., Miles, J. & 9 others, Larijani, B., Kunene, V., Fontana, E., Arkenau, H., Parker, P. J., Rodriguez-justo, M., Shiu, K., Spencer, J. & Ciccarelli, F. D., Oct 2021, In: Gastroenterology. 161, 4, p. 1179-1193 15 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1053/j.gastro.2021.06.064 Co-ordinated control of the Aurora B abscission checkpoint by PKCϵ complex assembly, midbody recruitment and retention Watson, L., Soliman, T. N., Davis, K., Kelly, J., Lockwood, N., Yang, X., Lynham, S., Scott, J. D., Crossland, V., McDonald, N. Q., Mann, D. J., Armstrong, A., Eggert, U. & Parker, P. J., 25 Jun 2021, In: Biochemical Journal. 478, 12, p. 2247-2263 17 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1042/BCJ20210283 Quantification of biomarker functionality predicts patient outcomes Larijani, B., Miles, J., Ward, S. G. & Parker, P. J., 11 May 2021, In: British journal of cancer. 124, 10, p. 1618-1620 3 p. Research output: Contribution to journal › Comment/debate › peer-review. DOIs: https://doi.org/10.1038/s41416-021-01291-3 ImmunoCluster provides a computational framework for the non-specialist to profile high- dimensional cytometry data Opzoomer, J. W., Timms, J. A., Blighe, K., Mourikis, T. P., Chapuis, N., Bekoe, R., Kareemaghay, S., Nocerino, P., Apollonio, B., Ramsay, A. G., Tavassoli, M., Harrison, C., Ciccarelli, F. D., Parker, P., Fontenay, M., Barber, P. R., Arnold, J. N. & Kordasti, S., Apr 2021, In: eLife. 10, e62915. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.7554/eLife.62915 Equivocal, explicit and emergent actions of PKC isoforms in cancer Parker, P. J., Brown, S. J., Calleja, V., Chakravarty, P., Cobbaut, M., Linch, M., Marshall, J. J. T., Martini, S., McDonald, N. Q., Soliman, T. & Watson, L., Jan 2021, In: NATURE REVIEWS CANCER. 21, 1, p. 51-63 13 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1038/s41568-020-00310-4 Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data Timms, J. A., Opzoomer, J. W., Blighe, K., Apollonio, B., Mourikis, T., Chapuis, N., Bekoe, R., Ramsay, A. G., McLornan, D. P., Harrison, C., Barber, P. R., Parker, P., Fontenay, M., Arnold, J. N. & Kordasti, S., 5 Nov 2020, In: Blood. 136 Research output: Contribution to journal › Meeting Abstract › peer-review. DOIs: https://doi.org/10.1182/blood-2020-140258 A small molecule inhibitor of HER3: a proof-of-concept study Colomba, A., Fitzek, M., George, R., Weitsman, G., Roberts, S., Zanetti-Domingues, L., Hirsch, M., Rolfe, D. J., Mehmood, S., Madin, A., Claus, J., Kjaer, S., Snijders, A. P., Ng, T., Martin-Fernandez, M., Smith, D. M. & Parker, P. J., 18 Sep 2020, In: THE BIOCHEMICAL JOURNAL. 477, 17, p. 3329-3347 19 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1042/BCJ20200496 High PD-1/PD-L1 checkpoint interaction infers tumor selection and therapeutic sensitivity to anti-PD-1/PD-L1 treatment Parker, P., 27 Aug 2020, In: Cancer Research. Research output: Contribution to journal › Article › peer-review View all publications