Mass spectrometry (MS) is a powerful, high-sensitivity technology for identifying and quantifying peptides, proteins, lipids, small molecules, trace elements, and metals. By ionizing molecules and measuring their mass-to-charge ratios, MS delivers precise molecular and elemental insights with exceptional accuracy and dynamic range.

When combined with separation techniques such as liquid or gas chromatography, mass spectrometry enables comprehensive analysis of complex samples across proteomics, performed in the Thermo Orbitrap Astral and lipidomics, metabolomics, and elemental research, performed on the Thermo Orbitrap Ascend.

Advanced spatial approaches, including laser ablation with inductively coupled plasma mass spectrometry (ICP-MS), further extend capabilities to trace metal detection and quantification using the Thermo iCAP MTX Triple Quad. Spatial peptide, metabolite, and lipid analysis allows for localisation at the cellular and subcellular level using the Bruker timsToF Flex MALDI 2 system.

With its sensitivity, specificity, and multiplexing power, mass spectrometry is an essential platform for biomarker discovery, pathway analysis, environmental testing, and clinical research.