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World AIDS Day: IPS researchers finding innovative ways to prevent HIV

King’s College London is leading an €5.8 million project funded by the European Commission aimed at developing new ways to prevent the spread of HIV.  

A team of researchers from the Dental Institute and Institute of Pharmaceutical Sciences at King’s have joined forces to work on developing gels that will optimise microbicides against the virus. 

Microbicides are drugs that can be applied topically to vaginal or rectal surfaces to prevent infection with HIV. The MOTIF(Microbicide Optimisation Through Innovative Formulation for Vaginal and Rectal Delivery) project is investigating mechanisms involved in drug distribution at these surfaces and using the findings to inform development of gel formulations with improved delivery of microbicides to target cells in the tissues.

MOTIFis a collaborative project that involves eight partners from four countries within the European Union and one partner from the USA.  Dr Ben Forbes, Institute of Pharmaceutical Science, said: ‘We are proud to be applying our expertise in drug transport towards the development of a licensed medicine for the prevention of HIV infection.’