Mariana de Carvalho Lima
150 Stamford Street
London, SE1 9NH
Present: Undergratuate student (2008-2013) at the Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (Brazil).
Since 2010, she has worked in the spin-off Essentii, which is developing drug-sustained release systems to treat periodontal disease, using complexes of biopolymers cross-linked with glutaraldehyde.
Mariana is currently a visiting researcher (funded by the University of São Paulo, Academic Merit grant programme), studying the complex coacervation of casein (dairy protein) and pectin (polysaccharide from plants), to produce microcapsules to improve the sustained release of model drugs. These systems will be cross-linked by the enzyme transglutaminase, which displays lower toxicity than other more commonly used cross-linking agents. Design parameters are systematically varied and optimized and their impact on the structure of the microcapsules and their rheology studied.