Show/hide main menu

PBG Alumni

Dr Louic S. Vermeer

Vermeer, Louic140x180Biophysique des Membranes et RMN

Institut de Chimie (UMR-7177)

1, rue Blaise Pascal

Universite de Strasbourg

67000 Strasbourg

France

Email: online@louic.nl

Website: http://louic.nl 

Google Scholar Citation Index

About Louic

Louic completed his PhD at the Université Paul Sabatier, Toulouse, France in 2009 before joining the group as a post-doc funded by the MRC. Louic is expert in a variety of biophysical methods, in particular both liquid and solid-state NMR and has considerable experience in molecular dynamics simulations.

His research now focuses on obtaining experimentally validated models of the interactions of cationic peptides with biomembranes and developing both HR-MAS and CP-MAS metabolomic methods and software. 

Louic left the group in 2012 after a very productive spell and continued his research in the Biomembrane Structure Unit with Prof. Tony Watts in the Department of Biochemistry, University of Oxford before moving to the University of Strasbourg to work in the group of Prof. Burkhard Bechinger.

Publications
  1. Amos, S-B.T.A., Vermeer, L.S., Kozlowska, J., Davy, M., Ferguson, P., Bui, T.T., Drake, A.F., Lorenz, C.D. & Mason, A.J. Antimicrobial peptide potency is facilitated by greater conformational flexibility when binding to Gram-negative bacterial innner membranes. Scientific Reports 2016 (6) 37639
  2. Kozlowska, J., Vermeer, L.S., Rogers, G.B., Rehnnuma, N., Amos, S-B.T.A., Koller, G., McArthur, M., Bruce, K.D. & Mason, A.J.* Combined systems approaches reveal highly plastic responses to antimicrobial peptide challenge in Escherichia coli. PLoS Pathogens 2014 (10) e1004104.
  3. Abbate, V., Liang, W., Patel, J., Lan, Y., Capriotti, L., Iacobucci, V., Bui, T.T., Chaudhuri, P., Kudsiova, L., Vermeer, L.S., Chan, P.F.L., Kong, X., Drake, A.F., Lam, J.K.W., Bansal, S.S. & Mason, A.J. Manipulating the pH response of 2,3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity. J. Control. Release2013 (172) 929-938
  4. Kozlowska, J., Rivett, D.W., Vermeer, L.S., Carroll, M.P., Bruce, K.D., Mason, A.J. & Rogers, G.B. A relationship between Pseudomonal growth behaviour and cystic fibrosis patient lung function identified in a metabolomic investigation. Metabolomics 2013 (9) 1262-1273
  5. Vermeer, L.S., Lan, Y., Abbate, V., Ruh, E., Bui, T.T., Wilkinson, L., Kanno, T., Jumagulova, E., Kozlowska, J., Patel, J., McIntyre, C.A., Yam, W.C., Siu, G., Atkinson, R.A., Lam, J.K.W., Bansal, S.S., Drake, A.F., Mitchell, G.H. & Mason, A.J.Conformational flexibility determines selectivity and anti-bacterial, antiplasmodial and anticancer potency of cationic α-helical peptides. J. Biol. Chem. 2012 (287) 34120-34133
  6. Stressman, F.A., Rogers, G.B., van der Gast, C.J., Marsh, P., Vermeer, L.S., Carroll, M.P., Hoffman, L.R., Daniels, T.W.V., Patel, N., Forbes, B. & Bruce, K.D.  Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resilience. Thorax 2012 (67) 867-873
  7. Vermeer, L.S., Fruhwirth, G.O., Pandya, P., Ng, T. & Mason, A.J. NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation. J. Proteome Res. 2012 (11) 2996-3003
  8. Iacobucci, V., Di Giuseppe, F., Bui, T.T., Vermeer, L.S., Patel, J., Scherman, D., Kichler, A., Drake, A.F. & Mason, A.J. Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer. Biochim. Biophys. Acta 1818 (2012) 1332-1341
  9. Jawad, R., Elleman, C., Vermeer, L.S., Drake, A.F., Woodhead, B., Martin, G.P. & Royall, P.G. The measurement of the β/α anomer composition within amorphous lactose prepared by spray and freeze drying using a simple 1H-NMR method. Pharmaceutical Research 29 (2011) 511-524
  10. Lan, Y., Langlet-Bertin, B., Abbate, V., Vermeer, L.S, Kong, X., Sullivan, K., Leborgne, C., Scherman, D., Hider, R.C., Drake, A.F., Bansal, S.S, Kichler, A. & Mason, A.J. Incorporation of 2,3-diaminopropionic acid in linear cationic amphipathic peptides produces pH sensitive vectors. ChemBioChem 11 (2010), 1266-1272
  11. Vermeer, L.S., Reat, V., Hemminga, M.A. & Milon, A. Structural properties of a peptide derived from H+-V-ATPase subunit a. BBA Biomembranes 1788 (2009), 1204-1212
  12. Vermeer, L.S., de Groot, B.L., Reat, V. Milon, A. & Czaplicki, J.  Acyl chain order parameter profiles in phospholipid bilayers: computation from molecular dynamics simulations and comparison with 2H NMR experiments. European Biophysics Journal 36 (2007), 919-931
  13. Vos, W.L., Vermeer, L.S. & Hemminga, M.A. Conformation of a Peptide Encompassing the Proton Translocation Channel of Vacuolar H+-ATPase. Biophysical Journal 92 (2007), 138--146
  14. Vos, W.L., Vermeer, L.S., Wolfs, C.J.A.M., Spruijt, R.B. & Hemminga, M.A. Decomposition of ESR Spectra Using MALDI-TOF Mass Spectrometry. Analytical Chemistry 78 (2006), 5296--5301 
Sitemap Site help Terms and conditions  Privacy policy  Accessibility  Modern slavery statement  Contact us

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454