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Professor Andrew Pickles

Professor Andrew Pickles

  • Academics
  • Supervisors

Professor of Biostatistics and Psychological Methods

Research subject areas

  • Biomedical and life sciences
  • Psychology

Contact details


My career has passed through universities in the UK and US and has spanned natural, social and medical sciences.  My research in the field of mental health and neurodevelopment, was strongly influenced by a spell as statistician in Michael Rutter’s MRC Unit at the Institute of Psychiatry from 1986 to 1998. This gave rise to long-term collaborations with Catherine Lord, Emily Simonoff and many other exceptional scientists and colleagues, and which has focused largely on children, particularly those with autism. A collaboration with Sophia Rabe-Hesketh also led to the development of the gllamm program and the framework for multilevel generalized structural equation modelling. Ten years at the University of Manchester allowed additional collaborations in language development with Gina Conti-Ramsden among others. I returned to King's College London (KCL) Institute of Psychiatry, Psychology & Neuroscience (IoPPN) in 2010 as Head of Biostatistics and Director of KCL’s Clinical Trials Unit. An important more recent shift has been towards the study of infants and early developmental signals and processes. Much of my methodological work has dealt with longitudinal models for developmental data and the many and varied impacts of measurement error and how these can be overcome.  I am a fellow of the Academy of Medical Sciences, a National Institute for Health Research Senior Investigator and highly cited scientist. 

Research Interests: 

  • Statistical methods for developmental data
  • Generalized structural equation modelling
  • Measurement, development and treatment of autism of autism
  • Measurement and development of language
  • Cohort studies


  • Generalized Structural Equation Modelling in Stata
  • Contemporary Psychometrics

Expertise and Public Engagement:

  • Academy of Medical Sciences
  • Academia Europea

Key Publications:

Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial 25 October 2016

Generalized multilevel structural equation modeling 01 June 2004

Epidemiological Methods in Life Course Research 2007