Miao Guo is a Reader in Autonomous Bioprocess Systems Engineering in the Department of Engineering at King's College London.

Her expertise spans biochemical engineering, mathematical modelling and optimisation, and AI for Science. Her research group develops mathematical and optimisation methods, computational tools, and high-throughput experimental–computational platforms for the design and optimisation of biotechnologies based on microbial monocultures and communities. A major focus is the conversion of low-grade carbon and nutrient resources, often regarded as waste, into valuable products such as microbial protein.

Her recent research focuses on autonomous bioprocessing, integrating AI Scientist systems with robotic experimental platforms to create closed-loop scientific discovery workflows. These systems are designed to autonomously generate and test scientific hypotheses, design and execute experiments, interpret results, and refine mechanistic understanding of biological systems.

Research Interests

• AI for Science
• Autonomous bioprocess systems and self-driving laboratories
• Optimisation and mathematical programming
• Process modelling, simulation and optimisation
• Hybrid and mechanistic modelling
• Biotechnology for wastewater treatment and resource recovery
• Microbial protein and sustainable biomanufacturing
• Life-cycle sustainability assessment

Further Information

• Research profile

• Github

• Guo Group