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Department of Psychosis Studies news

12 May 2017: Severe mental illness linked to much higher risk for cardiovascular disease and associated early death

An international study of more than 3.2 million people with severe mental illness reveals a substantially increased risk for developing cardiovascular disease compared to the general population.

02 May 2017: New IoPPN Dean appointed

The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) is pleased to announce that Professor Ian Everall has been appointed as IoPPN Executive Dean and will take up his position on 1 September 2017.

21 March 2017: Eight IoPPN researchers win prestigious NIHR Awards

Eight researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) have received NIHR (National Institute for Health Research) Senior Investigator awards.

02 March 2017: King's experts ask: can cannabis be made safer?

As cannabis laws become liberalised in many countries, experts from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London argue that there is an urgent need to explore how cannabis use can be made safer.

15 February 2017: Neuropsychiatry is about mental health problems that occur in the context of brain disease.

Multiple sclerosis (MS) affects about 150-200 people per 100,000 in the UK and is commonly associated with psychiatric problems especially depression. Psychosis in the context of multiple sclerosis has previously been reported as a rare occurrence. However, recent epidemiological studies have found prevalence rates of psychosis in MS that are two to three times higher than those in the general population. Untreated psychosis in patients with MS can adversely impact on adherence to MS medication, levels of disability, and quality of life.  

We have recently published a retrospective case series in the journal Neuropsychiatric Disease and Treatment, which describes the spectrum of psychotic disorders occurring in association with MS using demographic, clinical, and neuroimaging data.

Read more

This was a collaboration between clinicians and academics at King’s College Hospital, the Maudsley Hospital and the IoPPN. 

There appear to be 3 groups of patients: those who have a psychosis and then develop MS; those that have established MS and then develop a psychosis (often with other cognitive difficulties). Finally there is a rare but interesting group in whom the psychosis and evidence of MS seem to come to light at around the same time. 

In the discussion, we highlight the particular diagnostic and treatment challenges that such disorders can pose for clinicians and through our case vignettes provide examples of potential interventions for this complex patient population. 

This case series gives a good illustration of what clinical neuropsychiatry is all about. Find out more about our brand new Master’s programme.


11 January 2017: Schizophrenia could directly increase risk of diabetes

People with early schizophrenia are at an increased risk of developing diabetes, even when the effects of antipsychotic drugs, diet and exercise are taken out of the equation, according to an analysis by researchers from King's College London.
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