Two micro-machining laser units offer flexibility to execute sophisticated parts in different materials (metals, polymers and ceramic). Working area of 300 x 300 mm2, motion range of ± 100 mm, and equipped with high precision rotary chuck for small tubes (1.27 mm and a wall thickness of 0.15 mm).

A unique process capable of joining dissimilar materials like ceramic to titanium that delivers both high levels of hermetic performance and RF transparency. Working volume of 8 litres (200 x 200 x 200 mm3) and motion range of ± 50 mm.

Furnaces and oven for nitinol shape setting, annealing, tempering, ceramic sintering and firing. Chamber size for high temperature (1,600 C) of 7.5 litres, and 30 litres for lower temperatures. RTP (Rapid Thermal Processing) furnace has a chamber size of 0.4 litres and controlled atmosphere.

• Micro-milling EDM (Electrical Discharge Machining) executes high precision and complex parts
• The electrode removes material by spark erosion, drilling holes as small as 45 microns in diameter and as large as 3 mm, in a working area of 0.04 sqm (300 x 150 mm2)

Wide range of coating deposition system for both metals and organics/polymers using sputter, e-beam and thermal evaporation sources.

A hydraulic hot press with a platen area of 200 x 200 mm2 will laminate HTCC and multilayer hybrids in a continuous temperature (maximum of 250 C). The complete production on printed circuits is inside cleanroom grade ISO-7, including firing and sintering of ceramic components.

Flexible and high-performance equipment to populate the circuit boards:
• Pick and place (semi-automatic)
• Fine Placer System (for precise positioning and reflow)
• Wire-bonder
• Parallel gap welder

Micro-milling EDM (Electrical Discharge Machining) executes high precision and complex parts. The electrode removes material by spark erosion, drilling holes as small as 45 microns in diameter and as large as 3 mm, in a working area of 0.04 sqm (300 x 150 mm2).

State of the art 3D printing system using different technologies, aiming to manufacture high-quality parts focusing our process in small sizes (maximum of 0.7 litres) using PA2200 Nylon, Ti64 titanium alloy, alumina ceramic and high performance polymers.

Anne’s research is in the field of neurotechnologies, from technological innovations to their interactions with the (human) nervous system. She develops technology for the next generation of implantable electronic devices to improve the quality of life of patients, through applications such as: neuromodulation and electrical stimulation for the restoration of movement in paralysed muscles; and biopotential recording for control of prosthesis and artificial organs. Anne is the Director of MAISI, a national facility for the Manufacture of Active Implants and Surgical Instruments housed at St Thomas' hospital. MAISI is not only a unique facility to manufacture the most complex medical devices, but the team also brings together engineers and experts in regulatory affairs to support researchers, whether in academia or SMEs, to bring their ideas to the first tests in humans.
Anne trained as an engineer in Belgium (ULB) and the Netherlands (Eindhoven), then had the opportunity to undertake a PhD under the supervision of Prof Donaldson in the Implanted Devices Group at UCL. She has worked in Germany (IMTEK, Freiburg) and Australia (UNSW, Sydney), where she was fortunate to meet some of the most influential people in her career. Anne is also a keen teacher with a concern for Diversity Equality and Inclusivity, and actively seeks new strategies to develop more inclusive learning spaces and improve the university experience of non-mainstream students. She has been an active member of the International Microelectronics Assembly and Packaging Society (IMAPS-UK) since 2012.
Opportunities to join MAISI or her research team as a PhD student or postdoc are regularly advertised through King's webpages and on LinkedIn. You can also view Anne's people page.

Gabriel joined the school of BMEIS and MAISI team in the early stages of the project to assist with the conceptualisation of the cleanroom and required manufacturing processes. He has a deep technical and operational process experience combined with a talent for data-driven innovation. Gabriel is a Mechanical Engineer with more than 15 years’ experience at a leading pharmaceutical and medical device company where he managed several projects in multiple countries.

Dr Clare Heaysman is the Medical Engineering Quality Systems Manager in the Wellcome /EPSRC Centre for Medical Engineering. Clare started working with academic groups on applying the design practices adopted by regulated industries in translational research projects in 2014. She also has 10 years’ experience working in industry on the design and development of drug device combination products for interventional oncology, generating intellectual property and working on the technical transfer from academic and industrial partners.

Michael joined King’s College London in January 2021 as a Process Engineer for the School of Biomedical Engineering & Imaging Sciences. He is responsible for the development and delivery of the new facility for the manufacture of active implants and surgical instruments (MAISI) and the associated manufacturing equipment and processes. After graduating from the University of Hull with a first-class degree in Mechanical Engineering, Michael spent 5 years at a leading medical device company where he held various Engineering focused roles and developed several multimillion-dollar processes for new and existing medical device products.

Laurence joined King’s College London in July 2019 as the Research Administrator for The Centre of Medical Engineering supporting researchers and fellows with major projects. Laurence has been involved in some major grants and projects including KCL Check (research study on the impact of Covid-19). He joined the MAISI team in July 2021 as the Operations Officer for the facility and as well as the directors PA, he is currently working on the MAISI’s marketing and branding strategy as well as supporting the team with the projected timelines.

Hannah joined MAISI in early 2022 as Regulatory and Clinical Research Associate. Having previously worked for the Medicines and Healthcare products Regulatory Agency delivering post-EU exit regulatory change, she provides customers and internal project teams at KCL with expert advice on medical device regulations and assists with the clinical translation of research prototypes.

Kam Kahlon joined MAISI in 2022 as Manufacturing Quality Assurance Lead to provide quality support in designing and establishing a new cleanroom facility for the production of first-in-patient medical devices. Kam transferred from another flagship clinical manufacturing facility within KCL where she spent 20 years working in various roles.

Fintan joined MAISI in early 2023 as Quality and Compliance Officer providing quality support in establishing a new cleanroom facility for the production of first-in-patient medical devices. Fintan spent over 6 years in leading GMP Contract Manufacturing and Research Organisations where he held various Quality positions supporting release and manufacture of ATMP and Biologic products used in clinical trials and commercial batch release.