Professor Snezhana Oliferenko
Professor of Cell Biology
Wellcome Trust Senior Investigator
Email: snezhana.oliferenko@kcl.ac.uk
Biography
Reader in Cell Biology
2013 – present. Randall Division of Cell and Molecular Biophysics, King’s College London
Senior Principal Investigator
2010 – 2013. Temasek Life Sciences Laboratory, Singapore
Principal Investigator
2005 – 2010. Temasek Life Sciences Laboratory, Singapore
Young Investigator
2002 – 2005. Temasek Life Sciences Laboratory, Singapore
Postdoctoral
2000 – 2002. Institute of Molecular Agrobiology, Singapore
PhD
1996 – 1999. Institute of Molecular Pathology, Vienna, Austria
Undergraduate
1989 – 1994. Diploma in Biochemistry (MSc Degree), Department of Virology, Lomonosov Moscow State University, Moscow, Russia
Publications
- Gu, Y., Yam, C. and S. Oliferenko. Rewiring of cellular division site selection in evolution of fission yeasts. Current Biology. 25:1187-1194
- He, Y., Yam, C., Pomraning, K., Chin, J., Yew, J., Freitag, M. and S. Oliferenko. 2014. Increase in cellular triacylglycerol content and emergence of unusual ER-bound lipid droplets in the absence of CDP-DG synthase function. Molecular Biology of the Cell (doi:10.1091/mbc.E14-03-0832, in press)
- Zhang, D. and S. Oliferenko. 2014. Tts1, the fission yeast homolog of TMEM33 family, functions in NE remodeling during mitosis. Molecular Biology of the Cell. 25: 2970-298
- Yam, C., Gu, Y. and S. Oliferenko. 2013. Partitioning and remodeling of the Schizosaccharomyces japonicus mitotic nucleus require chromosome tethers. Current Biology. 23:2303-2310
- Vjestica, A., Zhang, D. and S. Oliferenko. 2013. Hsp70-Hsp40 chaperone complex functions in controlling polarized growth by repressing Hsf1-driven heat stress associated transcription PLoS Genetics. 9: e1003886. doi:10.1371/journal.pgen.1003886
- Zhang, D. and S. Oliferenko. 2013. Remodeling the nuclear membrane during closed mitosis. Current Opinions in Cell Biology. 25:142-148.
- Zhang, D., Vjestica, A. and S. Oliferenko. 2012. Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture. Current Biology. 22:2048-2052.
- Vjestica, A. and S. Oliferenko. 2012. Nuclear geometry: Mitotic nucleus flares out when arrested. Current Biology. 22:R489-491.
- Gu, Y., Yam, C. and S. Oliferenko. 2012. Divergence of mitotic strategies in fission yeasts. Nucleus. 3(3):1-6.
- Yam, C., He, Y., Zhang, D., Chiam, K. and S. Oliferenko. 2011. Divergent strategies for controlling the nuclear membrane satisfy geometric constraints during nuclear division. Current Biology. 21:1314-1319.
- Thadani, R., Huang, D. and S. Oliferenko. 2011. Robust polarity specification operates above a threshold of microtubule dynamicity. Cytoskeleton. 68:290-299.
- Castagnetti, S., Oliferenko, S. and P. Nurse. 2010. Fission yeast cells undergo nuclear division in the absence of spindle microtubules. PLoS Biology 8(10): e1000512. doi:10.1371/journal.pbio.1000512.
- Zhang, D., Vjestica, A. and S. Oliferenko. 2010. The cortical ER network limits the permissive zone for actomyosin ring assembly. Current Biology. 20:1029-1034.
- Thadani, R., Ling, Y. C. and S. Oliferenko. 2009. The fission yeast TACC protein Mia1p stabilizes microtubule arrays by length-independent crosslinking. Current Biology. 19:1861-1868.
- Ling, Y. C., Vjestica, A. and S. Oliferenko. 2009. Nucleocytoplasmic shuttling of the TACC protein Mia1p/Alp7p is required for remodeling of microtubule arrays during the cell cycle. PLoS ONE. 4:e6255.
- Oliferenko, S., Chew, T. G. and M. Balasubramanian. 2009. Positioning cytokinesis. Genes and Development. 23:660-674.
- Mishra, M. and S. Oliferenko. 2008. Cytokinesis: Catch and drag. Current Biology. 18:R247-250.
- Vjestica, A., Tang, X.-Z. and S. Oliferenko. 2008. The actomyosin ring recruits early secretory compartments to the division site in fission yeast. Molecular Biology of the Cell. 19:1125-1138.
- Zheng, L., Schwartz, C., Magidson, V., Khodjakov, A. and S. Oliferenko. 2007. The spindle pole bodies facilitate nuclear envelope division during closed mitosis in fission yeast. PLoS Biology 5(7): e170 doi:10.1371/journal.pbio.0050170 (7): e170 doi:10.1371/journal.pbio.0050170
- Huang, Y., Tran, P., Oliferenko, S. and M. Balasubramanian. 2007. Assembly of microtubules and actomyosin rings in the absence of nuclei and spindle pole bodies revealed by a novel genetic method. PLoS ONE. 2:e618.
- Zheng, L., Schwartz, C., Wee, L-M., and S. Oliferenko. 2006. The fission yeast TACC-related protein, Mia1p/Alp7p, is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope. Molecular Biology of the Cell. 17:2212-2222.
- Rajagopalan, S., A. Bimbo, M. Balasubramanian and S. Oliferenko. 2004. A potential tension sensing mechanism that ensures timely anaphase onset upon metaphase spindle orientation. Current Biology. 14: 69-74.
- Wang H, Oliferenko S, and Balasubramanian MK. 2003. Cytokinesis: relative alignment of the cell division apparatus and the mitotic spindle. Curr Opin Cell Biol. 15:82-87.
- Oliferenko S. and M. Balasubramanian. 2002. Astral microtubules monitor metaphase spindle alignment in fission yeast. Nature Cell Biology, 4: 816-820.
- Liu J., Tang X., Wang H. Y., Oliferenko S. and M. Balasubramanian. 2002. The localization of the integral membrane protein Cps1p to the cell division site is dependent on the actomyosin ring and the septation-inducing network in Schizosaccharomyces pombe. Mol. Biol. Cell, 13: 989-1000.: 989-1000.
- Oliferenko S. and M. Balasubramanian. 2001. Cell cycle: the Flp side of Cdc14. Current Biology, 11:R872-874.
- Schwärzler C., Oliferenko S. and U. Günthert. 2001. Variant isoforms of CD44 are required in early thymocyte development. Eur. J. Immunology, 31:2997-3005.
- Oliferenko S., Kaverina I., J. V. Small and Huber L. A. 2000. Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth. J. Cell Biol. 148:1159-1164.
- Oliferenko S., Paiha K., Harder T., Gerke V., Schwärzler C., Schwarz H., Beug H., Günthert U. and Huber L.A. 1999. Analysis of CD44-containing lipid rafts: recruitment of annexin II and stabilization by the actin cytoskeleton. J. Cell Biol. 146:843-854.
- Legras S., Günthert U., Stauder R., Curt F., Oliferenko S., Kluin-Nelemans C., Marie J.P., Vernant J. P., Proctor S., Chomienne C., Pico J.L., Jasmin C. and Smadia-Joffe F.: 1998. A strong expression of CD44-6v is associated with poor prognosis in Acute Myeloid Leukemia. Blood. 91:3401-3413