Professor Claire Wells Academics Supervisors Associate Dean for Doctoral Studies Professor in Cancer Cell Biology. Research subject areas Biomedical and life sciences Cancer Contact details claire.wells@kcl.ac.uk +44 (0) 2078488769
Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells Murugesan, G., Prescott, A. R., Toth, R., Campbell, D. G., Wells, C. M. & MacKintosh, C., 31 Aug 2022, In: THE BIOCHEMICAL JOURNAL. 479, 16, p. 1709-1725 17 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1042/BCJ20220184 PAK-dependent regulation of actin dynamics in breast cancer cells Best, M., Gale, M. E. & Wells, C. M., 31 May 2022, In: International Journal of Biochemistry and Cell Biology. 146, 106207. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.biocel.2022.106207 Invadopodia play a role in prostate cancer progression Manuelli, V., Cahill, F., Wylie, H., Gillett, C., Correa, I., Heck, S., Rimmer, A., Haire, A., Van Hemelrijck, M., Rudman, S. & Wells, C., 16 Mar 2022, (Accepted/In press) In: BMC Cancer. 22, 1, 386. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1186/s12885-022-09424-4 p21-Activated Kinase 1 Promotes Breast Tumorigenesis via Phosphorylation and Activation of the Calcium/Calmodulin-Dependent Protein Kinase II Saldivar-Cerón, H. I., Villamar-Cruz, O., Wells, C. M., Oguz, I., Spaggiari, F., Chernoff, J., Patiño-López, G., Huerta-Yepez, S., Montecillo-Aguado, M., Rivera-Pazos, C. M., Loza-Mejía, M. A., Vivar-Sierra, A., Briseño-Díaz, P., Zentella-Dehesa, A., Leon-Del-Rio, A., López-Saavedra, A., Padierna-Mota, L., Ibarra-Sánchez, M. D. J., Esparza-López, J., Hernández-Rivas, R., & 1 othersArias-Romero, L. E., 17 Jan 2022, In: Frontiers in Cell and Developmental Biology. 9, 759259. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fcell.2021.759259 Exosome-mediated RNAi of PAK4 prolongs survival of pancreatic cancer mouse model after loco-regional treatment Xu, L., Faruqu, F. N., Lim, Y. M., Lim, K. Y., Liam-Or, R., Walters, A. A., Lavender, P., Fear, D., Wells, C. M., Tzu-Wen Wang, J. & Al-Jamal, K. T., Jan 2021, In: Biomaterials. 264, 120369. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.biomaterials.2020.120369 Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases De Piano, M., Manuelli, V., Zadra, G., Otte, J., Edqvist, P-H., Ponten, F., Nowinski, S., Niaouris, A., Grigoriadis, A., Loda, M., Van Hemelrijck, M. & Wells, C. M., 30 Apr 2020, In: Oncogene. 39, 18, p. 3666–3679 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41388-020-1243-2 PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells (vol 29, pg 3385, 2019) Foxall, E., Staszowska, A., Hirvonen, L. M., Georgouli, M., Ciccioli, M., Rimmer, A., Williams, L., Calle, Y., Sanz-Moreno, V., Cox, S., Jones, G. E. & Wells, C. M., 21 Apr 2020, In: Cell Reports. 31, 3 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.celrep.2020.107593 Exploring a role for fatty acid synthase in prostate cancer cell migration De Piano, M., Manuelli, V., Zadra, G., Loda, M., Muir, G., Chandra, A., Morris, J., Van Hemelrijck, M. & Wells, C. M., 1 Jan 2020, (Accepted/In press) In: Small GTPases. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1080/21541248.2020.1826781 PlexinB1 Promotes Nuclear Translocation of the Glucocorticoid Receptor Williamson, M. P., Garg, R. & Wells, C. M., 18 Dec 2019, (E-pub ahead of print) In: Cells. 9, 1, cells9010003. Research output: Contribution to journal › Article › peer-review PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells Foxall, E., Staszowska, A., Hirvonen, L. M., Georgouli, M., Ciccioli, M., Rimmer, A., Williams, L., Calle, Y., Sanz Moreno, V., Cox, S., Jones, G. E. & Wells, C. M., 10 Dec 2019, In: Cell Reports. 29, 11, p. 3385-3393.e6 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.celrep.2019.11.016 View all publications
17 September 2020 Researchers find novel treatment strategy for pancreatic cancer in cross-discipline collaborative study A new cross-discipline collaborative study presents a novel treatment strategy for pancreatic cancer…