Our cross-cutting Basic Cardiac and Metabolic Investigations Theme is led by Dr Giancarlo Forte and underpins our research across all sites.
Understanding cardiovascular disease, diabetes and obesity requires an integrated, multidisciplinary approach that spans molecular mechanisms, cellular systems, whole-organ physiology and clinical translation. Our School brings together more than 50 principal investigators who undertake a diverse portfolio of fundamental research aimed at uncovering the mechanisms that drive human disease.
Our mission is to support and amplify this research by fostering collaborations across disciplines, promoting innovation and accelerating pathways to clinical translation. We aim to create an environment in which discoveries made at the bench can be rapidly connected to patient needs and clinical opportunities through our close partnership with King's Health Partners and the School's Clinical Research theme.
The School provides access to state-of-the-art facilities and expertise, including high-throughput screening, high-content imaging, multimodal in vivo imaging, proteomics, advanced viral and non-viral vector platforms, cellular and integrative physiology, and 3D advanced disease models.
Together, these platforms enable investigators to study disease mechanisms across scales, from molecules to patients.
The theme actively promotes cutting-edge research by connecting investigators with complementary expertise, encouraging the development of new technologies and model systems, and supporting multidisciplinary research programmes. Beyond collaboration within the School, we facilitate partnerships across King's College London, with national and international centres of excellence, and through strategic collaborations with institutions including the University of Pennsylvania, Göttingen Heart Centre and Dresden University, among others.
By combining excellence in fundamental discovery science with access to advanced experimental models, technologies and clinical expertise, the Basic Cardiac and Metabolic Investigations theme seeks to generate transformative insights into disease mechanisms and accelerate their translation into improved patient outcomes.