Professor Giovanna Lombardi Academics Supervisors Professor of Human Transplant Immunology Research subject areas Immunology
Regulatory T cell niche in the bone marrow, a new player in Haematopoietic stem cell transplantation Ashman, J., Mutsonziwa, N., Romano, M., Kordasti, S., Lombardi, G. & Shangaris, P., 31 Oct 2022, In: Blood Reviews. p. 101030 101030. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.blre.2022.101030 Transplantation Without Overimmunosuppression (TWO) study protocol: A phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients Brook, M. O., Hester, J., Petchey, W., Rombach, I., Dutton, S., Bottomley, M. J., Black, J., Abdul-Wahab, S., Bushell, A., Lombardi, G., Wood, K., Friend, P., Harden, P. & Issa, F., 15 Apr 2022, In: BMJ Open. 12, 4, e061864. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1136/bmjopen-2022-061864 Isolation and freezing of human peripheral blood mononuclear cells from pregnant patients Efthymiou, A., Mureanu, N., Pemberton, R., Tai-macarthur, S., Mastronicola, D., Scottà, C., Lombardi, G., Nicolaides, K. H. & Shangaris, P., 18 Mar 2022, In: STAR Protocols. 3, 1, 101204. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.xpro.2022.101204 Pluripotent stem cell-derived hepatocytes inhibit T cell proliferation in vitro through tryptophan starvation Romano, M., Elgueta, R., McCluskey, D., Ortega-Prieto, A. M., Stolarczyk, E., Dazzi, F., Lucendo-Villarin, B., Meseguer-Ripolles, J., Williams, J., Fanelli, G., Hay, D. C., Watt, F. M. & Lombardi, G., 1 Jan 2022, In: Cells. 11, 1, 24. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/cells11010024 Autocrine vitamin D signaling switches off pro-inflammatory programs of T Chauss, D., Freiwald, T., McGregor, R., Yan, B., Wang, L., Nova-Lamperti, E., Kumar, D., Zhang, Z., Teague, H., West, E. E., Vannella, K. M., Ramos-Benitez, M. J., Bibby, J., Kelly, A., Malik, A., Freeman, A. F., Schwartz, D. M., Portilla, D., Chertow, D. S., John, S., & 9 othersLavender, P., Kemper, C., Lombardi, G., Mehta, N. N., Cooper, N., Lionakis, M. S., Laurence, A., Kazemian, M. & Afzali, B., Jan 2022, In: Nature Immunology. 23, 1, p. 62-74 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41590-021-01080-3 Regulatory T Cells in Pregnancy Adverse Outcomes: A Systematic Review and Meta-Analysis Green, S., Politis, M., Rallis, K. S., Saenz de Villaverde Cortabarria, A., Efthymiou, A., Mureanu, N., Dalrymple, K. V., Scottà, C., Lombardi, G., Tribe, R. M., Nicolaides, K. H. & Shangaris, P., 29 Oct 2021, In: Frontiers in Immunology. 12, 1 p., 737862. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2021.737862 Regulatory T Cells in Pregnancy adverse Outcomes (Rutepo): A Systematic Review & Meta-Analysis Green, S., Politis, M., Rallis, K., Saenz de Villaverde CORTABARRIA, A., Efthymiou, A., Mureanu, N., Dalrymple, K., Scotta, C., Lombardi, G., Tribe, R., Nicolaides, K. & Shangaris, P., 29 Oct 2021, In: Frontiers in immunology. 12, 737862. Research output: Contribution to journal › Article › peer-review Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance? Safinia, N., Vaikunthanathan, T., Lechler, R. I., Sanchez-Fueyo, A. & Lombardi, G., Oct 2021, In: European Journal of Immunology. 51, 10, p. 2373-2386 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/eji.202048875 Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive Mohseni, Y. R., Saleem, A., Tung, S. L., Dudreuilh, C., Lang, C., Peng, Q., Volpe, A., Adigbli, G., Cross, A., Hester, J., Farzaneh, F., Scotta, C., Lechler, R. I., Issa, F., Fruhwirth, G. O. & Lombardi, G., Oct 2021, In: European Journal of Immunology. 51, 10, p. 2522-2530 9 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/eji.202048934 Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency: Nox2-deficient Tregs improve heart allograft outcome Cellone Trevelin, S., Zampetaki, A., Sawyer, G., Ivetic, A., Brewer, A., Smith, L. A., Marelli-Berg, F. M., Köchl, R., Lechler, R. I., Shah, A. & Lombardi, G., 22 Sep 2021, In: JCI Insight. 6, 18, p. e149301 12 p., e149301. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1172/jci.insight.149301 View all publications