Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction: Mechanism of Treg depletion in AA Lim, S. P., Costantini, B., Mian, S. A., Abellan, P. P., Gandhi, S. A., Martinez-Llordella, M., Jose Lozano, J., Antunes Dos Reis, R., Povoleri, G. A. M., Mourikis, T. P., Abarrategi, A., Ariza-McNaughton, L., Heck, S., Irish, J. M., Lombardi, G., Marsh, J., Bonnet, D., Kordasti, S. & Mufti, G. J., 13 Aug 2020, In : Blood. 136, 7, p. 885-897 13 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1182/blood.2019001347 The Future of Regulatory T Cell Therapy: Promises and Challenges of Implementing CAR Technology Mohseni, Y., Tung, S. L., Dudreuilh, C., Lechler, R., Fruhwirth, G. & Lombardi, G., 24 Jul 2020, In : Frontiers in Immunology. 11, 1608. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.3389/fimmu.2020.01608 B lymphocytes contribute to indirect pathway T cell sensitization via acquisition of extracellular vesicles Becker, P. D., Ratnasothy, K., Sen, M., Peng, Q., Romano, M., Bazoer, J., Suvitra, E., Stout, A., Hylton, S. G., Dorling, A., Lechler, R. I., Smyth, L. A. & Lombardi, G., 2 Jun 2020, In : American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/ajt.16088 Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage Tung, S. L., Fanelli, G., Matthews, R. I., Bazoer, J., Letizia, M., Vizcay-Barrena, G., Faruqu, F. N., Philippeos, C., Hannen, R., Al-Jamal, K. T., Lombardi, G. & Smyth, L. A., 20 May 2020, In : Frontiers in Cell and Developmental Biology. 8, p. 317 317. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.3389/fcell.2020.00317 Beyond Bacterial Killing: NADPH oxidase 2 is an immunomodulator Cellone Trevelin, S., Shah, A. & Lombardi, G., May 2020, In : Immunology Letters. 221, p. 39-48 10 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1016/j.imlet.2020.02.009 IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis Catapano, M., Vergnano, M., Romano, M., Mahil, S. K., Choon, S-E., Burden, A. D., Young, H. S., Carr, I. M., Lachmann, H. J., Lombardi, G., Smith, C. H., Ciccarelli, F. D., Barker, J. N. & Capon, F., Apr 2020, In : Journal of Investigative Dermatology. 140, 4, p. 816-826.e3 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.jid.2019.08.444 The ONE Study: Evaluation of Regulatory Cell Therapy in Kidney Transplantation Using a Harmonized Trial Design Sawitzki, B., Harden, P., Reinke, P., Moreau, A., Hutchinson, J. A., Game, D. S., Tang, Q., Guinan, E., Battaglia, M., Burlingham, W. J., Roberts, I., Streitz, M., Josien, R., Böger, C. A., Scotta, C., Markmann, J. F., Hester, J., Juerchott, K., Braudeau, C., James, B. & 41 others, Contreras-Ruiz, L., van der Net, J. B., Bergler, T., Caldara, R., Petchey, W., Edinger, M., Dupas, N., Kapinsky, M., Mutzbauer, I., Otto, N. M., Ollinger, R., Hernandez Fuentes, M., Issa, F., Ahrens, N., Meyenberg, C., Karitzky, S., Kunzendorf, U., Knechtle, S. J., Grinyo, J., Morris, P. J., Brent, L., Bushell, A., Turka, L. A., Bluestone, J. A., Lechler, R., Schlitt, H. J., Cuturi, M. C., Schlickeiser, S., Friend, P. J., Miloud, T., Scheffold, A., Secchi, A., Crisalli, K., Kang, S-M., Hilton, R., Banas, B., Blancho, G., Volk, H-D., Lombardi, G., Wood, K. & Geissler, E. K., 20 Jan 2020, (Accepted/In press) In : The Lancet. 39 p. Research output: Contribution to journal - Article Getting to the Heart of the Matter: The role of Regulatory T-cells (Tregs) in Cardiovascular Disease (CVD) and Atherosclerosis Albany, C. J., Cellone Trevelin, S., Giganti, G., Lombardi, G. & Scottà , C., 28 Nov 2019, In : Frontiers in immunology. 10, 11 p., 2795. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.3389/fimmu.2019.02795 Applicability, Safety And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation Sánchez-Fueyo, A., Whitehouse, G., Grageda, N., Cramp, M. E., Lim, T. Y., Romano, M., Thirkell, S., Lowe, K., Fry, L., Heward, J., Kerr, A., Ali, J., Fisher, C., Lewis, G., Hope, A., Kodela, E., Lyne, M., Farzaneh, F., Kordasti, S., Rebollo-Mesa, I. & 5 others, Jose Lozano, J., Safinia, N., Lechler, R., Martínez-Llordella, M. & Lombardi, G., 12 Nov 2019, In : American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/ajt.15700 Regulatory B cells: Development, phenotypes, functions, and role in transplantation Alhabbab, R. Y., Nova-Lamperti, E., Aravena, O., Burton, H. M., Lechler, R. I., Dorling, A. & Lombardi, G., 1 Nov 2019, In : Immunological Reviews. 292, 1, p. 164-179 16 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1111/imr.12800 View all publications