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The Microscopy Innovation Centre is a Core Facility at King's College London and  collaborates with academic and industrial partners to develop and house advanced microscopy instrumentation and analysis tools, offering cutting-edge microscopes to support users in their advanced imaging needs.

Our vision is to be a hub for innovative microscopy, offering a comprehensive suite of advanced imaging techniques and analysis tools to the research community. By working with our research user base and strategic industry partners, we aim to build a world-class, unique facility that delivers advanced, non-commercial imaging solutions to the life science community to drive new discoveries in biomedical research.

The Microscopy Innovation Centre consists of two core team members, an Image Analyst and an academic steering committee. If you have imaging requirements that you have not been able to satisfy with commercial microscopy systems, or if you would like to collaborate with us on a novel microscopy method then we would like to hear from you.

Access

The MIC access policy includes details on access, eligibility, training, and our publication policy. We welcome all users from within King’s and the wider scientific and industrial communities. Enquiries should be directed to Dr Nicholas Anthony ( Facility Manager).

The MIC offers access and support in the use of advanced microscopy techniques to the wider community. Staffed by experienced microscopists, we provide user training and support alongside microscopy development, maintenance, and modifications.

We welcome new collaborations from research, industry, or companies. By offering our expertise, as well as demonstration and development space, we aim to be a hub in central London for innovative microscopy. Our bioImage analysis service, offers expert guidance and seasoned support in quantitative analysis and the development of image processing pipelines.

Facility staff

Nicholas Anthony

Manager - Microscopy Innovation Centre

Anisha Kubasik Thayil

Microscopy Innovation Centre - Deputy Manager

Stefania  Marcotti

Research Associate/ BioImage Analyst

Affiliated academics

Maddy Parsons

Dean of Research Excellence Frameworks

Reader in Cell Biophysics

Simon  Ameer-Beg

Professor in Optical Oncology

Siân Culley

Royal Society University Research Fellow

Stefania  Marcotti

Research Associate/ BioImage Analyst

UKRI Future Leaders Research Fellow

Having the scope to offer both cutting-edge ‘home-built’ microscopes, and innovative commercial systems, the MIC provides access to the latest in advanced microscopy techniques for the wider community. Our equipment is well supported by MIC staff, who perform ‘in-house’ maintenance and modifications, as well as user training and support.

Related equipment

JLLS
Janelia Lattice Light Sheet Microscope

Capturing rapid 3D imaging of live cells with multiple channels and low phototoxicity

microscope-385364_1920
STELLARIS 8 FALCON FLIM

The STELLARIS 8 FALCON (FAst Lifetime CONtrast) is our easy-to-use microscope optimised for Fluorescence Lifetime IMaging (FLIM).

microscope-385364_1920
ABBELIGHT SAFe 360 (Arriving Autumn, 2024)

the Abbelight SAFe 360 is a system capable of widefield imaging, 2D and 3D Single Molecule Localisation Microscopy and Total Internal Reflection Fluorescence

microscope-385364_1920
Innovation Collection

We offer optomechanical parts for long and short term loans

We work with research leaders to secure funding and new equipment. This has included partnering with Prof. Simon Ameer-Beg to house the ‘discoSPIM’ (Prof. Maddy Parsons, Wellcome Leap, 2021), and with Dr. Susan Cox to build our Janelia Lattice Light sheet (BBSRC Alert, 2018).

We perform our own experiments, and develop tools with researchers and industrial partners. In 2021 we received funding from the Royal Microscopy Society’s to interact with industrial partners (Nano Clinical, Nikon) on two short projects to develop novel microscopy approaches.

Publications 

Geraldine M. Jowett, Michael D. A. Norman, Tracy T. L. Yu, Patricia Rosell Arévalo, Dominique Hoogland, Suzette T. Lust, Emily Read, Eva Hamrud, Nick J. Walters, Umar Niazi, Matthew Wai Heng Chung, Daniele Marciano, Omer S. Omer, Tomasz Zabinski, Davide Danovi, Graham M. Lord, Jöns Hilborn, Nicholas D. Evans, Cécile A. Dreiss, Laurent Bozec, Oommen P. Oommen, Christian D. Lorenz, Ricardo M. P. da Silva, Joana F. Neves & Eileen Gentleman. (2021) ILC1 drive intestinal epithelial and matrix remodelling, Nat. Mat. 20, 250–259.

Karin Pfisterer, James A. Levitt, Campbell D. Lawson, Richard J. Marsh, John M. Heddleston, Eric Wait, Simon M. Ameer-Beg, Susan Cox, Maddy Parsons. (2020) FMNL2 regulates dynamics of fascin in filopodia. J. Cell Biol. 4 May 2020; 219 (5):e201906111.

James A. Levitt, Simon P. Poland, Nikola Krstajic, Karin Pfisterer, Ahmet Erdogan, Paul R. Barber, Maddy Parsons, Robert K. Henderson & Simon M. Ameer-Beg. (2020) Quantitative real-time imaging of intracellular FRET biosensor dynamics using rapid multi-beam confocal FLIM, Sci. Rep. 10, 5146. 

What is BioImage Analysis?

BioImage analysis entails the application of computational techniques to extract quantitative information from images with biological relevance. Tasks include identifying specific objects, evaluating morphological features, and quantifying signals in defined regions of interest. The ultimate goal is to automate these operations into reproducible pipelines, facilitating precise and reliable measurements crucial for scientific advancements.

Areas of expertise:

  • Quantitative image analysis
  • FLIM interpretation

Connecting with the BioImage Analysis Service:

  • Dr. Stefania Marcotti, BioImage Analysis Specialist invites researchers and microscopy facility users to explore the service. Initial consultations are free of charge.  
  • Training Opportunities: The team are organising training sessions to empower researchers with the skills needed for effective image analysis. Watch this space for more information and upcoming dates. 
  • Light Microscopy Core Facilities at King's: Visit the Nikon Imaging Centre (Dr. Dylan Herzog) and Microscopy Innovation Centre (Dr. Nicholas Anthony) for more information.
  • Contact: Dr. Nicholas Anthony at nicholas.anthony@kcl.ac.uk or Dr. Stefania Marcotti at stefania.marcotti@kcl.ac.uk

The MIC offers access and support in the use of advanced microscopy techniques to the wider community. Staffed by experienced microscopists, we provide user training and support alongside microscopy development, maintenance, and modifications.

We welcome new collaborations from research, industry, or companies. By offering our expertise, as well as demonstration and development space, we aim to be a hub in central London for innovative microscopy. Our bioImage analysis service, offers expert guidance and seasoned support in quantitative analysis and the development of image processing pipelines.

Facility staff

Nicholas Anthony

Manager - Microscopy Innovation Centre

Anisha Kubasik Thayil

Microscopy Innovation Centre - Deputy Manager

Stefania  Marcotti

Research Associate/ BioImage Analyst

Affiliated academics

Maddy Parsons

Dean of Research Excellence Frameworks

Reader in Cell Biophysics

Simon  Ameer-Beg

Professor in Optical Oncology

Siân Culley

Royal Society University Research Fellow

Stefania  Marcotti

Research Associate/ BioImage Analyst

UKRI Future Leaders Research Fellow

Having the scope to offer both cutting-edge ‘home-built’ microscopes, and innovative commercial systems, the MIC provides access to the latest in advanced microscopy techniques for the wider community. Our equipment is well supported by MIC staff, who perform ‘in-house’ maintenance and modifications, as well as user training and support.

Related equipment

JLLS
Janelia Lattice Light Sheet Microscope

Capturing rapid 3D imaging of live cells with multiple channels and low phototoxicity

microscope-385364_1920
STELLARIS 8 FALCON FLIM

The STELLARIS 8 FALCON (FAst Lifetime CONtrast) is our easy-to-use microscope optimised for Fluorescence Lifetime IMaging (FLIM).

microscope-385364_1920
ABBELIGHT SAFe 360 (Arriving Autumn, 2024)

the Abbelight SAFe 360 is a system capable of widefield imaging, 2D and 3D Single Molecule Localisation Microscopy and Total Internal Reflection Fluorescence

microscope-385364_1920
Innovation Collection

We offer optomechanical parts for long and short term loans

We work with research leaders to secure funding and new equipment. This has included partnering with Prof. Simon Ameer-Beg to house the ‘discoSPIM’ (Prof. Maddy Parsons, Wellcome Leap, 2021), and with Dr. Susan Cox to build our Janelia Lattice Light sheet (BBSRC Alert, 2018).

We perform our own experiments, and develop tools with researchers and industrial partners. In 2021 we received funding from the Royal Microscopy Society’s to interact with industrial partners (Nano Clinical, Nikon) on two short projects to develop novel microscopy approaches.

Publications 

Geraldine M. Jowett, Michael D. A. Norman, Tracy T. L. Yu, Patricia Rosell Arévalo, Dominique Hoogland, Suzette T. Lust, Emily Read, Eva Hamrud, Nick J. Walters, Umar Niazi, Matthew Wai Heng Chung, Daniele Marciano, Omer S. Omer, Tomasz Zabinski, Davide Danovi, Graham M. Lord, Jöns Hilborn, Nicholas D. Evans, Cécile A. Dreiss, Laurent Bozec, Oommen P. Oommen, Christian D. Lorenz, Ricardo M. P. da Silva, Joana F. Neves & Eileen Gentleman. (2021) ILC1 drive intestinal epithelial and matrix remodelling, Nat. Mat. 20, 250–259.

Karin Pfisterer, James A. Levitt, Campbell D. Lawson, Richard J. Marsh, John M. Heddleston, Eric Wait, Simon M. Ameer-Beg, Susan Cox, Maddy Parsons. (2020) FMNL2 regulates dynamics of fascin in filopodia. J. Cell Biol. 4 May 2020; 219 (5):e201906111.

James A. Levitt, Simon P. Poland, Nikola Krstajic, Karin Pfisterer, Ahmet Erdogan, Paul R. Barber, Maddy Parsons, Robert K. Henderson & Simon M. Ameer-Beg. (2020) Quantitative real-time imaging of intracellular FRET biosensor dynamics using rapid multi-beam confocal FLIM, Sci. Rep. 10, 5146. 

What is BioImage Analysis?

BioImage analysis entails the application of computational techniques to extract quantitative information from images with biological relevance. Tasks include identifying specific objects, evaluating morphological features, and quantifying signals in defined regions of interest. The ultimate goal is to automate these operations into reproducible pipelines, facilitating precise and reliable measurements crucial for scientific advancements.

Areas of expertise:

  • Quantitative image analysis
  • FLIM interpretation

Connecting with the BioImage Analysis Service:

  • Dr. Stefania Marcotti, BioImage Analysis Specialist invites researchers and microscopy facility users to explore the service. Initial consultations are free of charge.  
  • Training Opportunities: The team are organising training sessions to empower researchers with the skills needed for effective image analysis. Watch this space for more information and upcoming dates. 
  • Light Microscopy Core Facilities at King's: Visit the Nikon Imaging Centre (Dr. Dylan Herzog) and Microscopy Innovation Centre (Dr. Nicholas Anthony) for more information.
  • Contact: Dr. Nicholas Anthony at nicholas.anthony@kcl.ac.uk or Dr. Stefania Marcotti at stefania.marcotti@kcl.ac.uk

Partners

nikon

Nikon

Euro BioImaging Logo

Euro BioImaging

Nano Clinical

Nano Clinical

Contact us

3rd Floor, Hodgkin Building Guys Campus King’s College London London, SE1 1UL

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