Research
Meet the FODMAP team:
Research publications:
So D, Whelan K, Rossi M, Morrison M, Holtmann G, Kelly JT, Shanahan ER, Staudacher HM, Campbell KL. Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis. Am J Clin Nutr. 2018; 107: 965-983.
https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/nqy041
Staudacher HM, Kurien M, Whelan K. Nutritional implications of dietary interventions for managing gastrointestinal disorders. Curr Opin Gastro. 2018; 34: 105–111.
https://insights.ovid.com/pubmed?pmid=29278531
Healey G, Murphy R, Butts C, Brough L, Whelan K, Coad J. Habitual dietary fibre intake influences gut microbiota response to an inulin-type fructan prebiotic: a randomised, double-blind, placebo-controlled, cross-over, human intervention study. Brit J Nutr. 2018; 119: 176-189.
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/habitual-dietary-fibre-intake-influences-gut-microbiota-response-to-an-inulintype-fructan-prebiotic-a-randomised-doubleblind-placebocontrolled-crossover-human-intervention-study/637C3E930108F079BD8DB4049562449C
Lever E, Scott SM, Louis P, Emery PW, Whelan K. The effect of prunes on stool output, gut transit time and gastrointestinal microbiota: a randomised controlled trial. Clin Nutr. 2018 (in press).
https://www.sciencedirect.com/science/article/pii/S0261561418300037?via%3Dihub
Whelan K, Martin LD, Staudacher HM, Lomer MC. The low FODMAP diet in the management of irritable bowel syndrome: an evidence-based review of FODMAP restriction, reintroduction and personalisation in clinical practice. J Hum Nutr Diet. 2018; 31: 239-255.
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jhn.12530/abstract
Rossi M, Aggio R, Staudacher HM, Lomer MC, Lindsay JO, Irving PM, Probert C, Whelan K. Volatile organic compounds in feces associate with response to dietary intervention in patients with irritable bowel syndrome. Clin Gastro Hep 2018; 16: 385-391.
https://www.sciencedirect.com/science/article/pii/S1542356517312016?via%3Dihub
Dimidi E, Rossi M, Whelan K. Irritable bowel syndrome and diet: where are we in 2018? Current Opinion Clinical Nutr Metab 2017; 20: 456-463.
https://insights.ovid.com/pubmed?pmid=28872467
Staudacher HM, Lomer MCE, Farquharson FM, Louis P, Fava F, Franciosi E, Scholz M, Tuohy KM, Lindsay JO, Irving PM, Whelan K. Diet low in FODMAPs reduces symptoms in patients with irritable bowel syndrome and probiotic restores bifidobacterium species: a randomized controlled trial. Gastroenterology. 2017; 153: 936–947.
https://www.sciencedirect.com/science/article/pii/S001650851735744X
Staudacher HM, Whelan K. The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in irritable bowel syndrome. Gut. 2017; 66: 1517-1527.
http://gut.bmj.com/content/66/8/1517.long
Cox SR, Prince AC, Myers CE, Irving PM, Lindsay JO, Lomer MC, Whelan K. Fermentable carbohydrates (FODMAPs) exacerbate functional gastrointestinal symptoms in patients with inflammatory bowel disease: a randomised, double-blind, placebo-controlled, cross-over, re-challenge trial. J Crohns Colitis. 2017; 11: 1420-1429.
https://academic.oup.com/ecco-jcc/article/11/12/1420/3835798
Prince A, Myers CM, Joyce T, Irving PM, Lomer MC, Whelan K. Fermentable carbohydrate restriction (low FODMAP diet) in clinical practice improves functional gastrointestinal symptoms in patients with inflammatory bowel disease. Inflamm Bowel Disease. 2016; 22: 1129-1136.
https://academic.oup.com/ibdjournal/article-abstract/22/5/1129/4561787
Staudacher HM, Whelan K. Altered gastrointestinal microbiota in irritable bowel syndrome and its modification by diet: probiotics, prebiotics and the low FODMAP diet. Proc Nutr Soc. 2016; 75: 306-18.
https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/altered-gastrointestinal-microbiota-in-irritable-bowel-syndrome-and-its-modification-by-diet-probiotics-prebiotics-and-the-low-fodmap-diet/8A7E00D44BD17B2F192D8EEBE464AD03
Whigham L, Joyce T, Harper G, Irving PM, Staudacher HM, Whelan K, Lomer MC. Clinical effectiveness and economic costs of group versus one-to-one education for short-chain fermentable carbohydrate restriction (low FODMAP diet) in the management of irritable bowel syndrome. J Hum Nutr Diet. 2015; 28: 687–696.
http://onlinelibrary.wiley.com/doi/10.1111/jhn.12318/abstract;jsessionid=4A829E182C549618033ADBE57DBBD8DD.f02t01
Anderson JL, Hedin CR, Benjamin JL, Koutsoumpas A, Ng SC, Hart AL, Forbes AF, Stagg AJ, Lindsay JO, Whelan K. Dietary intake of inulin-type fructans in active and inactive Crohn’s disease and healthy controls: a case-control study. J Crohn’s Colitis. 2015; 9: 1024-31.
https://academic.oup.com/ecco-jcc/article/9/11/1024/404546
Staudacher HM, Irving PM, Lomer MC, Whelan K. Mechanisms and efficacy of dietary FODMAP restriction in IBS. Nature Gastro Hep. 2014; 11: 256-266.
https://www.nature.com/articles/nrgastro.2013.259
Dimidi E, Christodoulides S, Fragkos KC, Scott SM, Whelan K. The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. Am J Clin Nutr. 2014; 100: 1075–84.
https://academic.oup.com/ajcn/article/100/4/1075/4576460
Staudacher HM, Lomer MC, Anderson JL, Barrett JS, Muir JG, Irving PM, Whelan K. Fermentable carbohydrate restriction reduces luminal bifidobacteria and gastrointestinal symptoms in patients with irritable bowel syndrome. J Nutr. 2012; 142: 1510-8.
https://academic.oup.com/jn/article/142/8/1510/4630946
Staudacher H, Whelan K, Irving P, Lomer MCE. Comparison of symptom response following advice for a diet low in fermentable carbohydrates (FODMAPs) versus standard dietary advice in patients with irritable bowel syndrome. J Hum Nutr Diet. 2011; 24: 487-495.
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-277X.2011.01162.x/abstract
Studies underway:
- A feasibility study on education delivery methods for a low fermentable carbohydrate (FODMAP) diet in patients with irritable bowel syndrome in primary care.
- Prebiotic supplementation in ulcerative colitis to assess the effect on markers of gut inflammation.
- Dietary intake in patients with inflammatory bowel disease (a survey).
- Microbiological and physiological effects of dietary supplementation with fibre in irritable bowel syndrome: a randomised controlled trial.
- Dietary interventions for functional gastrointestinal symptoms in quiescent inflammatory bowel disease.