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Centre for Stem Cells & Regenerative Medicine

Visiting Speakers

The Centre for Stem Cells & Regenerative Medicine is proud to host a series of seminars by international speakers on a regular basis.  

All are welcome - no need to RSVP.

Location for all seminars: 

Seminar Room, CSCRM 28th floor, Tower Wing, Guy's campus
(Please follow signs for "Seminar Room 2" from the 28th floor lift lobby)

Upcoming seminars in 2018/2019:


TUESDAY 11th DECEMBER 2018, 4:00pm - 5:00pm


Dr Masato Nakagawa (Junior Associate Professor, CiRO, Kyoto University)

"MYC function and efficient methods for hiPSC generation"

Visiting Speaker - 2018-12-11 - Masato Nakagawa

Induced pluripotent stem (iPS) cells which are able to differentiate into all cell types in our bodies raise great hopes for application in regenerative medicine. iPS cells can be established from ordinary skin cells with four transgenic factors delivered by a retroviral vector. These four factors - Sox2, Oct3/4, Klf4, and c-Myc - are all regulators of gene expression, and by expressing them in somatic cells, we can change the expression state of the cells, a process known as “reprogramming”. Before iPS cells can be used in clinical applications, issues surrounding their safety must be resolved. Research in mice has shown that the retrovirally delivered factor c-Myc can trigger tumor formation. Recent work from our lab has revealed that L-Myc, another member of the c-Myc family, can also be used in the establishment of iPS, with a gain in efficiency of 5 to 10 fold. In addition, the risk of tumorigenesis has not been shown for L-Myc derived iPS cells. The mechanisms by which L-Myc participates in iPS cell derivation, however, remain unclear, and further study will be needed. We collaborate broadly to define the full potential of iPS for cell therapy, drug discovery and toxicity studies



WEDNESDAY 12th DECEMBER 2018, 4:00pm - 5:00pm


Dr Sara Wickstrom (Associate Professor, Univeristy of Helsinki)

"Regulation of stem cell fate by niche-derived signals and forces"

Visiting Speaker - 2018-12-12---Wickstrom---Pic---Cropped-for-WebSara Wickström studied medicine at the University of Helsinki, Finland, receiving her MD in 2001 and PhD in 2004. After postdoctoral training with Reinhard Fässler at the Max Planck Institute for Biochemistry in Munich, Germany,she was appointed as Group Leader at the Max Planck Institute for Biology of Ageing in Cologne, Germany in 2010. In 2018 her laboratory moved to the newly founded Helsinki Institute for Life Science at the University of Helsinki, Finland. Research in the Wickström lab aims to establish quantitative principles of epidermal stem cell niche self-organization, and how mechanical forces and cellular interactions integrate single cell behaviors to generate and maintain global patterns of a multicellular tissue.



WEDNESDAY 16th JANUARY 2018, 4:00pm - 5:00pm


Professor Anne Grapin Botton (University of Copenhagen)

Visiting Speaker - 2019-01-16---Grapin-Botton---Pic---Cropped-for-WebProfessor Grapin-Botton and her group investigate the impact of the cellular and organ architecture on the cells’ fate choices and how single cells act in a community to generate an organ. To do so, they use mouse genetics, live imaging in 3D and they developed 3D in vitro “organoid” culture systems modelling development. More recently they used human in vitro stem cell models investigate human development. These studies are intended to gain insight into human syndromes impairing pancreas development and they guide the generation of replacement beta cells for Diabetes therapy


MONDAY 18th FEBRUARY 2018, 4:00pm - 5:00pm


Professor James Wells (Director for Research, Division of Endocrinology / Chief Scientific Office, Center for Stem Cell and Organoid Medicine (CuSTOM, Cincinatti Children's Hospital)

Visiting Speaker - 2019-02-18---Wells---Pic---Cropped. for web

Research in the Wells lab aims to understand the development of the pancreas, and gastrointestinal organs; generating 3-dimensional human tissues from pluripotent stem cells and using these as human models of diabetes and digestive disease.

The focus of his teams basic research has been to identify the molecular mechanisms involved in the embryonic development of endocrine cells including pancreatic beta cells and tissues of the gastrointestinal tract. Their translational projects have focused on identifying new approaches to improve child health in several ways: 1. To identify and use embryonic pathways to generate complex, three-dimensional organ tissues from pluripotent stem cells, 2. Use these tissues to develop new in vitro human models for diabetes and digestive disease research and 3. Develop long-term, therapeutic strategies for cell and tissue-replacement therapies.



                                     Please keep checking here for

                             details of forthcoming speakers in 2017


Our fortnightly Stem Cells @ Lunch seminars and our weekly Journal Club meetings are open to all... 


The Second Workshop on High Content Screening of Stem Cells took place at King's in September 2015. A link to the keynote lecture by Dr Anne Carpenter (Broad Institute of MIT and Harvard) is available here: 
High-Content Morphology Profiling for Targeting Diseases and Characterizing Compounds

Blank space Previous visiting speakers

Dr Meritxell Huch - Cambridge University
"Liver progenitors and hepatic organoids" (Nov 2018)

Prof Bart De Strooper - UK Dementia Research Institute and University of Leuven
"Alzheimer’s disease is moving from a biochemical to a cellular view" (Nov 2018)

Prof Sarah Stabenfeldt - Arizona State University
"Bioengineering approaches to address neural injury from regenerative medicine to nanotherapeutics" (Sept 2018)

Dr Duncan Sutherland - Aarhus University
"Nanostructured matierals surfaces to study and control adherent cells" (June 2018)

Dr Kathy Green - Northwestern University
"How Cadherins created a complex epithelia" (May 2018)

Dr Jonah Cool - Chan Zuckerberg Initiative
"Chan Zuckerberg and the Human Cell Atlas" (March 2018)

Prof Janet Rossant - University of Toronto
"From embryos to stem cells and back again - a developemntal journey" (November 2017)

Prof Jody Rosenblatt - University of Utah
"Epithelial Cell Extrusion and its misregulation in asthma and cancer" (September 2017)

Prof Virgile Viasnoff - National University of Singapore
"A mechano-biologicy perspective on apico-basal polarisation" (July 2017)

Prof Dany Nassar - Université Paris Descartes and American University of Beirut
"Genomic landscapes and sources of tumour heterogeneity of cutaneous squamous cell carcinoma" (June 2017)

Dr Ed Boyden - MIT Media Lab and McGovern Institute MIT
"Optical tools for understanding biology: Expansion microscopy, optogenetic and more" (June 2017)

Dr Wei-Yu Lu - Edinburgh University
"The liver repopulating capacity of hepatic progenitor cells" (April 2017)

Dr Nadia Zeltner - Memorial Sloane Kettering Institute
"Modelling Didease of the peripherla nervous system" (April 2017)

Dr Liesbet Lieben - Nature Reviews Disease Primers
"How to write an article for Nature Reviews" (April 2017)

Dr Lev Silberstein - Harvard Department of Stem Cell and Regenerative Biology
"Single cell analysis of the bone marrow niche identifies novel regulators of the hematopoetic regeneration" (March 2017)

Dr Peter Rodgers - Features editor at eLife
"Reproducibility, reproducibility, reproducibility" (March 2017)

Dr Alessandra Vigilante - The Crick Institute, London "Uncovering links between genotype, cell behaviour and external stimuli by integrating different data sets from human induced pluripotent stem cell lines" (January 2017)

Dr Francesca Spagnoli - Junior Group Leader, Max-Delbrück-Center, Berlin, German and Adjunct Faculty Member, The Rockefeller University, New York, US

 "Controlling cell plasticity between liver and pancreas for regenerative medicine" (December 2016)

Dr Irving Weissman - Director, Institute of Stem Cell Biology and Regenerative Medicine Stanford University School of Medicine "Experiences with commercialising cell therapies" (November 2016) 

Dr Matthew Albert - Principal Scientist, Cancer Immunology, Genetech

"System’s Approach to Immune monitoring: a path towards establishing    genetic and environmental determinants of human immune variability" (November 2016)

Dr Vilja Pietiäinen - Senior Scientist, Institute for Molecular Medicine Finland [FIMM]
"High-content cell-based screening in translational biomedicine" (May 2016)

Professor Walter Birchmeier - Group Leader, Max Delbrueck Center for Molecular Medicine, Berlin
"Wnt/beta-catenin controls carcinomas and cancer stem cells by epigenetic mechanisms" (March 2016)

Dr Anjali P Kusumbe - 
Tissue Morphogenesis Department, Max Planck Institute for Molecular Biomedicine, Münster
"Regulation of stem and progenitor cell function by distinct vascular niches in bone" (March 2016)

Dr Alexis J Lómakin - Subcellular Structure and Cellular Dynamics, Institut Curie, Paris
"Competition principle in cellular morphogenesis" (February 2016)

Dr Ben Davies - Head of Transgenic Core Research Group, University of Oxford
"Application of CRISPR/Cas9 for the generation of genetically modified mouse models" (January 2016)

Dr Suzana Hadjur - Wellcome Trust Senior Research Fellow, UCL Cancer Institute
"Chromosome architecture and transcriptional regulation - A global role for CTCF and cohesin proteins" (November 2015)

Professor Jim Crilly - 
SVP Strategic Science Group, Global R&D, Unilever

"Innovation: making it happen. A perspective from 30 years at Unilever"(November 2015)

Dr Elizabeth Roper - Partner, Epidarex Capital

"VC investment in healthcare: what do we look for" (November 2015)

Professor Brigid Hogan FRS - George Barth Professor and Chair of the Department of Cell Biology, Duke University Medical Center, USA''The life of breath: Stem cells of the adult lung" (May 2015)

Mr Gregg Sando - Founder & CEO, Cell Medica"Cell Medica: from Conception to Corporation" (May 2015)

Professor Jason A. Burdick - Department of Bioengineering, University of Pennsylvania''Engineering Biomaterials as In Vitro Models and for Biomedical Therapies" (May 2015)

Professor Amy Wagers - Harvard University, Joslin Diabetes Center and Harvard Medical School''Targeting local and systemic factors to reverse age-related tissue dysfunction" (April 2015)

Professor Ken-ichiro Kamei - Institute for Integrated Cell-Material Sciences, Kyoto University: "Creating the right microenvironments for stem cell control" (February 2015)

Dr Sabine Hauert - Lecturer in Robotics, University of Bristol: 
"Crowdsourcing The Design of Swarming Nanosystems for Cancer Applications" (February 2015)

Dr Ignacio Sancho-Martinez - Belmonte Laboratory, Salk Institute for Biological Studies: 
"Reverting development by reprogramming. Are iSPCs the Holy Grail for regenerative medicine?" (October 2014)

Professor Randy Schekman - University of California, Berkeley 
Shared winner of the 2013 Nobel Prize in Physiology or Medicine
“Genes and proteins that control secretion and autophagy”(June 2014)(King's International Lecture Series - dedicated to Rosalind Franklin and hosted by King's Bioscience Institute)

Professor Lee Rubin - Department of Stem Cell and Regenerative, Biology, Harvard University, Director of Translational Medicine, Harvard Stem Cell Institute: 

“Motor Neuron Diseases in a Dish: Can we really learn anything new?” (January 2014)

Professor Konrad Hochedlinger - Center for Regenerative Medicine, Massachusetts General Hospital, USA, Professor of Medicine, Harvard Medical School:

'Mechanisms of pluripotency and cellular reprogramming' (January 2014)


Professor Alan Trounson – President of CIRM, San Francisco, USA: 

“The California Institute of Regenerative Medicine: How to invest $3 billion in stem cell research” (October 2013)

Professor Marianne Bronner – Albert Billings Ruddock Professor of Biology, California Institute of Technology, USA: 
“Transcriptional and epigenetic control of neural crest development” (September 2013)

Professor Peter Carlton – Research Center Assistant Professor & iCeMS Kyoto Fellow, Institute for Integrated Cell-Material Sciences, Kyoto University, Japan: 
“Cytological investigation of chromosome structure in meiosis and differentiation” (July 2013)

Dr Shukry J. Habib - Howard Hughes Medical Insitute 
“A localised Wnt signal orients assymetric stem cell division” (March 2013) 

Professor Willem H. Ouwehand – Professor of Experimental Haematology, University of Cambridge & Wellcome Trust Sanger Institute, NHS Bood and Transplant 
“New biological insights in the formation and function of platelets; lessons learned from genomics” (February 2013) 

Dr Deborah J. Sweet – Editor, Cell Stem Cell & Publishing Director, USA 
“Behind the scenes at Cell Press” (February 2013) 

Professor Irving Weissman – Professor, Stem Cell Institute & Stanford University School of Medicine, USA 
“Normal and neoplastic stem cells” (January 2013) 

Professor Kevin Eggan – Associate Professor, Department of Stem Cell and Regenerative Biology & Harvard Stem Cell Institute, Harvard University 
“Exploiting pluripotency for a greater understanding of neurological disease” (January 2013)

Prof Sarah Stabenfeldt - Arizona State University
"Bioengineering approaches to address neural injury from regenerative medicine to nanotherapeutics" (Sept 2018)Dr 
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