Wellcome Trust PhD Student Cohort 2018
I obtained my BSc Biochemistry degree at the University of Leeds. During the course, I spent a year working in UCB BioPharma in Belgium, joining the Investigative Toxicology group exploring novel biomarkers of drug-induced kidney injury. My main project focused on the evaluation of a novel urinary biomarker: Obajdin et. al (2018) FABP4 as a potential preclinical biomarker of drug-induced kidney injury. Journal of Toxicological Sciences. I also completed a final year project back in Leeds working on structural studies of a putative polyketide cyclase, IdmH, involved in the biosynthesis of indanomycin. I used a variety of structural techniques including X-ray crystallography which yielded the first solved structure of the protein!
The experience during both projects led me to pursue a career in research. I first became interested in stem cell research and regenerative medicine mainly through reading books and publications on the potential this field has in tissue repair, such as preventing organ failure and precluding the requirement for organ transplants. I chose this excellent PhD programme as it provides me with the opportunity to rotate through three different labs, covering a broad range of research areas, allowing me to gain a thorough understanding on the uses of stem cells in different applications. My first rotation is with Dr Alessandra Vigilante, learning how to use R and RStudio and the application of bioinformatics in the analysis of large data sets. We are working on results generated by the Malim Lab, using iPSCs to study the infectivity of HIV.
Jana Obajdin ORCID webpage