Wellcome Trust PhD Student Cohort 2018
I completed my undergraduate degree (MSci) in Genetics at University College London. I then spent two and a half years working as a research technician in Dr Filipe Cabreiro’s microbiology-metabolism lab, exploring the three-way host-microbiome-environment relationship using a C. elegans model.My interest in regeneration began during my master’s year research project. I observed close similarities but also distinctive differences in Notch signalling expression patterns between brittle star (invertebrate deuterostome) adult regeneration and embryonic development, mechanically and functionally. This suggests regeneration may be recapitulating development, at least partially. Therefore, my key research interest is to explore the extrinsic or intrinsic “switches” initiating regeneration.
The wide range of expertise in the Wellcome Trust ‘Cell Therapies and Regenerative Medicine’ Four-Year PhD Programme provides a golden opportunity to further my knowledge of the field through different models and disciplines. In my first rotation with Dr Cynthia Andoniadou, I will be exploring the molecular mechanisms “switching” stem cells in pituitary gland from quiescent to proliferative state. I am excited and looking forwards to dissecting this intriguing molecular network and gaining more in-depth knowledge of various fields through my first-year rotation projects.
Prudence Lui ORCID webpage