The newly established Centre for Nephrology, Urology and Transplantation within the School of Immunology and Microbial Sciences is the home for academic scholarship in basic and translational research, teaching, education and clinical innovation in diseases of the kidneys and urinary tract and the psychosocial support of patients with these diseases. It brings together research leaders, academics, clinicians and students from several disciplines who have established a productive track record and a collaborative environment with which to advance knowledge and understanding within the field.
Chronic kidney disease (CKD) has a global prevalence of 13%, with 1.2 million people dying every year from chronic kidney failure and another 1.7 million dying from acute kidney injury (AKI). CKD is strongly linked to cardiovascular disease with an estimated 1.2 million deaths and 18 million years of life lost from cardiovascular diseases being attributable to CKD.
Transplantation is the ‘gold standard’ treatment for CKD, but is still limited by three fundamental problems: the shortage of organs, the morbidity associated with immunosuppression, and the premature failure of transplanted organs. Urological diseases encompass a wide spectrum of different conditions, ranging from benign to highly malignant, which together present a high disease burden. For example, the prevalence of benign prostatic hypertrophy approaches 30% in elderly male populations and accounts for >£100 million annual NHS spend. By working together and in close collaboration with patients, we aim to advance fundamental knowledge in the field of Kidney and urological diseases, to develop new treatments and to improve the lives of those affected.
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